公开(公告)号：US20230152011A1

公开(公告)日：2023-05-18

申请号：US17989938

申请日：2022-11-18

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Amir SADRI ,  Nenad KIRCANSKI ,  Thanh-Vi TRAN ,  Carl MARLOWE ,  Brian David WILSON

IPC: F25B21/04 ,  B01L7/00 ,  H10N10/10 ,  H10N10/80

CPC classification number: F25B21/04 ,  B01L7/00 ,  B01L7/52 ,  H10N10/10 ,  H10N10/80 ,  B01L2300/1805 ,  B01L2300/08 ,  B01L2300/123

Abstract: A heat pump that includes a thermoelectric device(s) and a heat sink having a raised portion with a top surface for thermally coupling with a planar face of the thermoelectric device(s). The raised portion of the heat sink includes an outer periphery and a raised central region surrounded by a void region to provide more uniform thermal conductivity when clamped within an assembly. The raised central region is shaped in an any shape corresponding to a shape of uneven thermal conductivity due to clamping pressure applied to the heat sink. The void region can be substantially contiguous and entirely circumscribe the central raised region. The device can optionally include discrete supports formed of a less thermally-conductive material within the void region. The supports can be elastomeric, such as O-rings, and disposed within pockets defined within the void region.

公开(公告)号：US20220178874A1

公开(公告)日：2022-06-09

申请号：US17544591

申请日：2021-12-07

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kenneth OH ,  Carl MARLOWE ,  Stephen L. SWIHART ,  Evan THRUSH ,  Michael GRIFFIN

IPC: G01N27/447 ,  G01N33/68 ,  G01N21/64

Abstract: Methods and reference compositions for quantifying protein using tagged standards. In an exemplary method, a reference composition and a protein may be electrophoresed in respective lanes of a gel. The reference composition may include quantitation standards of different size and each including a tag present at a different concentration. The quantitation standards and the protein may be transferred from the gel to a solid support to create a blot. Luminescence may be detected from the blot to obtain respective luminescence values separately representing an abundance of the tag of each quantitation standard and an abundance of the protein. A quantity of the protein may be determined using the respective luminescence values.

公开(公告)号：US20230349892A1

公开(公告)日：2023-11-02

申请号：US18139829

申请日：2023-04-26

Applicant: Bio-Rad Laboratories, Inc.

Inventor： William STRONG ,  Eli HEFNER ,  Carl MARLOWE

IPC: G01N33/543 ,  G01N33/58

CPC classification number: G01N33/543 ,  G01N33/582 ,  G01N2458/10

Abstract: The disclosure provides a highly sensitive assay to detect the presence of a target analyte in a sample.

公开(公告)号：US20230199130A1

公开(公告)日：2023-06-22

申请号：US18082330

申请日：2022-12-15

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Stephen SWIHART ,  Evan THRUSH ,  Carl MARLOWE ,  Kenneth OH ,  Michael GRIFFIN

IPC: H04N1/10 ,  H04N1/028 ,  G06T5/50 ,  G06V10/141

CPC classification number: H04N1/1008 ,  H04N1/02865 ,  G06T5/50 ,  G06V10/141 ,  G06T2207/20221

Abstract: Systems and methods for contact imaging of stands with illumination are disclosed herein. A contact imaging system can include a contact imager. The contact imager can include a housing having a base and a lid. The lid can have a closed position against the base and an open position. The contact imager can include a contact area image sensor. The lid can shield the contact area image sensor from ambient light when the lid is in the closed position. The contact imager can include an illuminator that can illuminate at least a portion of a blot on the contact area image sensor when the lid is in the closed position.