公开(公告)号：US10449026B2

公开(公告)日：2019-10-22

申请号：US13928338

申请日：2013-06-26

申请人： Biostage, Inc.

发明人： Ron Sostek ,  David Green ,  Linghui Meng ,  Sherif Soliman ,  Joseph Consiglio

IPC分类号： A61F2/06 ,  A61F2/00 ,  A61L33/00 ,  A61F2/04 ,  A61F2/07 ,  D04H1/4382 ,  D01D5/00 ,  A61L27/34 ,  A61F2/02

摘要： Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

公开(公告)号：US12121629B2

公开(公告)日：2024-10-22

申请号：US17688676

申请日：2022-03-07

申请人： Biostage, Inc.

发明人： William Fodor ,  Linghui Meng ,  Sherif Soliman ,  Shunfu Hu

IPC分类号： A61L27/26 ,  A61L27/34 ,  A61L27/36 ,  A61L27/38 ,  A61L27/56

CPC分类号： A61L27/26 ,  A61L27/34 ,  A61L27/3679 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/3834 ,  A61L27/3882 ,  A61L27/56 ,  A61L2300/412 ,  A61L2420/06 ,  A61L2430/34

摘要： Aspects of the disclosure relate methods and synthetic scaffolds for regenerating hollow tubular organs present in the respiratory system such as bronchus tissue.

公开(公告)号：US20200085557A1

公开(公告)日：2020-03-19

申请号：US16565189

申请日：2019-09-09

申请人： Biostage, Inc.

发明人： Ron Sostek ,  David Green ,  Linghui Meng ,  Sherif Soliman ,  Joseph Consiglio

IPC分类号： A61F2/00 ,  D04H1/4382 ,  D01D5/00 ,  A61F2/07 ,  A61F2/04 ,  A61L27/34 ,  A61F2/02

摘要： Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

公开(公告)号：US12029638B2

公开(公告)日：2024-07-09

申请号：US17589096

申请日：2022-01-31

申请人： Biostage, Inc.

发明人： Saverio La Francesca ,  Sherif Soliman ,  Matthew Marsh ,  Shunfu Hu ,  Linghui Meng

IPC分类号： A61F2/04 ,  A61F2/00 ,  A61F2/07 ,  A61F2/82 ,  A61L27/04 ,  A61L27/18 ,  A61L27/38 ,  A61L27/56 ,  A61L27/58 ,  C12M1/12 ,  C12M3/00 ,  A61F2/90

CPC分类号： A61F2/04 ,  A61F2/0077 ,  A61F2/07 ,  A61F2/82 ,  A61L27/04 ,  A61L27/18 ,  A61L27/3834 ,  A61L27/56 ,  A61L27/58 ,  C12M21/08 ,  C12M25/14 ,  A61F2002/0086 ,  A61F2002/043 ,  A61F2002/044 ,  A61F2002/045 ,  A61F2002/046 ,  A61F2/90 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2230/0069 ,  A61F2250/0067 ,  A61L2430/22 ,  A61L27/18 ,  C08L75/04 ,  A61L27/18 ,  C08L67/02

摘要： Aspects of the disclosure relate methods and synthetic scaffolds for regenerating gastrointestinal tissue (e.g., esophageal tissue).

公开(公告)号：US11234805B2

公开(公告)日：2022-02-01

申请号：US16391212

申请日：2019-04-22

申请人： Biostage, Inc.

发明人： Saverio La Francesca ,  Sherif Soliman ,  Matthew Marsh ,  Shunfu Hu ,  Linghui Meng

IPC分类号： A61F2/04 ,  A61F2/07 ,  C12M3/00 ,  C12M1/12 ,  A61F2/00 ,  A61L27/04 ,  A61L27/18 ,  A61L27/38 ,  A61L27/56 ,  A61F2/82 ,  A61L27/58 ,  A61F2/90

摘要： Aspects of the disclosure relate methods and synthetic scaffolds for regenerating gastrointestinal tissue (e.g., esophageal tissue).

公开(公告)号：US12042369B2

公开(公告)日：2024-07-23

申请号：US16565189

申请日：2019-09-09

申请人： Biostage, Inc.

发明人： Ron Sostek ,  David Green ,  Linghui Meng ,  Sherif Soliman ,  Joseph Consiglio

IPC分类号： A61F2/02 ,  A61F2/00 ,  A61F2/04 ,  A61F2/06 ,  A61F2/07 ,  A61L27/34 ,  A61L27/48 ,  A61L27/56 ,  D01D5/00 ,  D04H1/4382

CPC分类号： A61F2/0063 ,  A61F2/02 ,  A61F2/04 ,  A61F2/07 ,  A61L27/34 ,  D01D5/0007 ,  D01D5/0084 ,  D04H1/43835 ,  D04H1/43838 ,  A61F2002/072 ,  A61F2210/00 ,  A61F2210/0071 ,  A61F2210/0076 ,  A61F2230/0069 ,  A61F2230/0091 ,  A61F2240/001 ,  A61F2250/0082

摘要： Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

公开(公告)号：US11464887B2

公开(公告)日：2022-10-11

申请号：US16592945

申请日：2019-10-04

申请人： Biostage, Inc.

发明人： Linghui Meng ,  Shunfu Hu ,  William Fodor

IPC分类号： A61L31/00 ,  A61L27/26 ,  A61L27/34 ,  A61L27/36 ,  A61L27/38 ,  A61L27/56

摘要： Aspects of the disclosure relate methods and a synthetic cell delivery device for treating trauma present relative to the inner surface of a hollow organ such as an esophagus.

公开(公告)号：US20220226097A1

公开(公告)日：2022-07-21

申请号：US17589096

申请日：2022-01-31

申请人： Biostage, Inc.

发明人： Saverio Francesca ,  Sherif Soliman ,  Matthew Marsh ,  Shunfu Hu ,  Linghui Meng

IPC分类号： A61F2/04 ,  A61F2/07 ,  C12M3/00 ,  C12M1/12 ,  A61F2/00 ,  A61L27/04 ,  A61L27/18 ,  A61L27/38 ,  A61L27/56 ,  A61F2/82 ,  A61L27/58

摘要： Aspects of the disclosure relate methods and synthetic scaffolds for regenerating gastrointestinal tissue (e.g., esophageal tissue).

公开(公告)号：US20230037735A1

公开(公告)日：2023-02-09

申请号：US17963013

申请日：2022-10-10

申请人： Biostage, Inc.

发明人： Linghui Meng ,  Shunfu Hu ,  William Fodor

IPC分类号： A61L27/26 ,  A61L27/34 ,  A61L27/36 ,  A61L27/38 ,  A61L27/56

摘要： Aspects of the disclosure relate methods and a synthetic cell delivery device for treating trauma present relative to the inner surface of a hollow organ such as an esophagus.

公开(公告)号：US20220257831A1

公开(公告)日：2022-08-18

申请号：US17688676

申请日：2022-03-07

申请人： Biostage, Inc.

发明人： William Fodor ,  Linghui Meng ,  Sherif Soliman ,  Shunfu Hu

IPC分类号： A61L27/26 ,  A61L27/34 ,  A61L27/36 ,  A61L27/38 ,  A61L27/56

摘要： Aspects of the disclosure relate methods and synthetic scaffolds for regenerating hollow tubular organs present in the respiratory system such as bronchus tissue.