METHOD FOR LOWERING THE DEPENDENCY TOWARDS SEQUENCE VARIATION OF A NUCLEIC ACID TARGET IN A DIAGNOSTIC HYBRIDIZATION ASSAY
    5.
    发明申请
    METHOD FOR LOWERING THE DEPENDENCY TOWARDS SEQUENCE VARIATION OF A NUCLEIC ACID TARGET IN A DIAGNOSTIC HYBRIDIZATION ASSAY 审中-公开
    降低依赖性在诊断杂交测定中核酸核酸靶序列变异的方法

    公开(公告)号:US20110236892A1

    公开(公告)日:2011-09-29

    申请号:US13058979

    申请日:2009-09-21

    IPC分类号: C12Q1/68 C07H21/00 C12P19/34

    CPC分类号: C12Q1/6876 C12Q2600/156

    摘要: A primer or/and probe for a target sequence containing at least one variation, defined as either one non-conserved nucleotide, called genotype variation, or one nucleotide variation within one and the same genotype, wherein the primer or/and probe has a nucleic acid sequence that is complementary to said target sequence except for the at least complementary base of the variation(s), which is not present in the primer or/and probe.

    摘要翻译: 用于靶序列的引物或/和探针,其含有至少一个定义为一个非保守核苷酸,称为基因型变异或一个和相同基因型内的一个核苷酸变异的变异体,其中该引物或/和探针具有核酸 除了引物或/和探针中不存在的变体的至少互补碱基之外,与所述靶序列互补的酸序列。