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公开(公告)号：US12098166B2
公开(公告)日：2024-09-24
申请号：US17291924
申请日：2019-11-05
发明人： Egbert Siegfried Mundt , Xiaoping Cui , Zenglei Hu
IPC分类号： C07K14/005 , A61K9/00 , A61K39/00 , A61K39/145 , A61K39/39 , A61P31/16 , C12N7/00 , C12N15/86 , G01N33/569
CPC分类号： C07K14/005 , A61K9/0019 , A61K39/145 , A61K39/39 , A61P31/16 , C12N7/00 , C12N15/86 , G01N33/56983 , A61K2039/5252 , A61K2039/54 , A61K2039/545 , A61K2039/552 , A61K2039/55566 , C12N2710/14043 , C12N2760/16122 , C12N2760/16134 , C12N2760/16152 , C12N2760/16163 , C12N2760/16171 , G01N2333/11 , G01N2469/10
摘要： The invention relates to the field of veterinary medicine. The invention provides an immunogenic composition, comprising a hemagglutinin protein of avian influenza virus H5 subtype. Also provided is a method of differentiating animals naturally infected with AIV from animals vaccinated with the immunogenic composition of the invention. The immunogenic composition of the invention can provide a broader, more effective, long-lasting and early onset protection on poultry.
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公开(公告)号：US11696947B2
公开(公告)日：2023-07-11
申请号：US16665465
申请日：2019-10-28
IPC分类号： A61K39/215 , C12N7/00 , A61P31/14 , A61K39/00
CPC分类号： A61K39/215 , A61P31/14 , C12N7/00 , A61K2039/5256 , A61K2039/552 , C12N2770/20021 , C12N2770/20022 , C12N2770/20034 , C12N2770/20071
摘要： The present invention relates i.a. to an H52 IBV (infectious bronchitis virus) encoding for a heterologous S (spike) protein or fragment thereof. Further, the present invention relates to an immunogenic composition comprising said H52 IBV encoding for a heterologous S (spike) protein or fragment thereof. Furthermore, the present invention relates to methods for immunizing a subject comprising administering to such subject the immunogenic composition of the present invention. Moreover, the present invention relates to methods of treating or preventing clinical signs caused by IBV in a subject of need, the method comprising administering to the subject a therapeutically effective amount of an immunogenic composition according to the present invention.
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公开(公告)号：US11998596B2
公开(公告)日：2024-06-04
申请号：US18067614
申请日：2022-12-16
发明人： Veljko Nikolin , Egbert Siegfried Mundt , Fernando Rodriguez Gonzalez , Laia Bosch Camos , Javier Alonso Collado Miguens
CPC分类号： A61K39/12 , C12N15/746 , C12N15/86 , A61K2039/552 , C12N2710/12022
摘要： The present invention relates to African swine fever virus (ASFV) peptides and/or polypeptides as well as immunogenic fragments thereof, corresponding encoding AFSV oligonucleotides and/or polynucleotides as well as immunogenic fragments thereof, immunogenic compositions, vaccines and uses thereof.
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公开(公告)号：US11628214B2
公开(公告)日：2023-04-18
申请号：US16830412
申请日：2020-03-26
发明人： Veljko Nikolin , Egbert Siegfried Mundt , Fernando Rodriguez Gonzalez , Laia Bosch Camos , Javier Alonso Collado Miguens
摘要： The present invention relates to African swine fever virus (ASFV) peptides and/or polypeptides as well as immunogenic fragments thereof, corresponding encoding AFSV oligonucleotides and/or polynucleotides as well as immunogenic fragments thereof, immunogenic compositions, vaccines and uses thereof.
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