公开(公告)号：US20230064786A1

公开(公告)日：2023-03-02

申请号：US17819126

申请日：2022-08-11

申请人： BOLT THREADS, INC.

发明人： David Breslauer ,  Joshua Kittleson ,  Loren Perelman ,  Lindsay Wray

IPC分类号： C07K14/435 ,  D01F4/00 ,  C12N15/81 ,  D01B7/00 ,  D02G3/04

摘要： The present disclosure provides improved long uniform recombinant protein fibers with desirable physical traits. The present disclosure also provides compositions derived from the long uniform recombinant protein fibers.

公开(公告)号：US11447532B2

公开(公告)日：2022-09-20

申请号：US15705185

申请日：2017-09-14

申请人： Bolt Threads, Inc.

发明人： David Breslauer ,  Joshua Kittleson ,  Loren Perelman ,  Lindsay Wray

IPC分类号： C07K14/435 ,  D01F4/00 ,  C12N15/81 ,  D01B7/00 ,  D02G3/04 ,  D01D5/06 ,  D06M101/12

摘要： The present disclosure provides improved long uniform recombinant protein fibers with desirable physical traits. The present disclosure also provides compositions derived from the long uniform recombinant protein fibers.

公开(公告)号：US20180111970A1

公开(公告)日：2018-04-26

申请号：US15705185

申请日：2017-09-14

申请人： Bolt Threads, Inc.

发明人： David Breslauer ,  Joshua Kittleson ,  Loren Perelman ,  Lindsay Wray

IPC分类号： C07K14/435 ,  C12N15/81 ,  D02G3/04 ,  D01B7/00

CPC分类号： C07K14/43518 ,  C12N15/81 ,  D01B7/00 ,  D01D5/06 ,  D01F4/00 ,  D02G3/042 ,  D06M2101/12 ,  D10B2211/04

摘要： The present disclosure provides improved long uniform recombinant protein fibers with desirable physical traits. The present disclosure also provides compositions derived from the long uniform recombinant protein fibers.

公开(公告)号：US20150293076A1

公开(公告)日：2015-10-15

申请号：US14437476

申请日：2013-10-22

申请人： Bolt Threads, Inc.

发明人： Daniel Widmaier ,  David Breslauer

IPC分类号： G01N33/50 ,  C07K14/00 ,  C07K14/435

CPC分类号： G01N33/5008 ,  C07K14/001 ,  C07K14/43518 ,  C07K2319/60 ,  C12N15/1034 ,  C12N15/1093

摘要： The present disclosure identifies methods and compositions for modifying organisms, such that the organisms are optimized to produce or are enhanced to produce proteins or metabolites from cells. The present disclosure relates to methods of strain optimization to produce or enhance production of proteins or metabolites from cells. The present disclosure also relates to compositions resulting from those methods.

摘要翻译： 本公开内容确定了用于修饰生物体的方法和组合物，使得生物被优化以产生或增强以从细胞产生蛋白质或代谢物。 本公开涉及应变优化的方法以产生或增强来自细胞的蛋白质或代谢物的产生。 本公开还涉及由这些方法得到的组合物。