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1.发明授权公开(公告)号：US12017074B2
公开(公告)日：2024-06-25
申请号：US17410489
申请日：2021-08-24
发明人： Rosana Esteller , Goran N. Marnfeldt , Natalie A. Brill , David M. Wagenbach , Pujitha Weerakoon , Jordi Parramon
CPC分类号： A61N1/36139 , A61N1/0553 , A61N1/36062 , A61N1/36171 , A61N1/36175 , A61N1/36185 , A61N1/37241
摘要： An Implantable Pulse Generator (IPG) or External Trial Stimulator (ETS) system is disclosed that is capable of sensing an Evoked Compound Action Potential (ECAP), and (perhaps in conjunction with an external device) is capable of adjusting a stimulation program while keeping a location of a Central Point of Stimulation (CPS) constant. Specifically, one or more features of measured ECAP(s) indicative of its shape and size are determined, and compared to thresholds or ranges to modify the electrode configuration of the stimulation program.
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公开(公告)号：US20210121701A1
公开(公告)日：2021-04-29
申请号：US17140850
申请日：2021-01-04
摘要： An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.
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公开(公告)号：US11724114B2
公开(公告)日：2023-08-15
申请号：US17020369
申请日：2020-09-14
发明人： Pujitha Weerakoon , David M. Wagenbach , Philip L. Weiss , Goran N. Marnfeldt , Kiran K. Gururaj
CPC分类号： A61N1/3758 , A61N1/36062 , A61N1/025 , A61N1/0534 , A61N1/378
摘要： An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.
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4.发明申请公开(公告)号：US20220142539A1
公开(公告)日：2022-05-12
申请号：US17648660
申请日：2022-01-21
摘要： Techniques for sensing neural responses such as Evoked Compound Action Potentials (ECAPs) in an implantable stimulator device are disclosed. A first therapeutic pulse phase is followed by a second pulse phase, which phases may be of opposite polarities to assist with active charge recovery. The second pulse phase is formed so as to overlap in time with the arrival of the ECAP at a sensing electrode, which second phase may generally be longer and of a lower amplitude. In so doing, a stimulation artifact formed in a patient's tissue is rendered constant, and of a smaller amplitude, when the ECAP is sensed at the sensing electrode, which eases sensing by a sense amp circuit. Passive charge recovery may follow the second phase, which will not interfere with ECAP sensing that has already occurred.
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公开(公告)号：US10786665B2
公开(公告)日：2020-09-29
申请号：US15695984
申请日：2017-09-05
发明人： Goran N. Marnfeldt , Philip L. Weiss , Pujitha Weerakoon , David M. Wagenbach , Emanuel Feldman , Kiran K. Gururaj
摘要： Digital-to-analog converter (DAC) circuitry for providing currents at electrodes of an Implantable Pulse Generator (IPG) is disclosed. The DAC circuitry includes at least one PDAC for sourcing current to the electrodes, and at least one NDAC for sinking current from the electrodes. The PDACs are powered with power supplies VH (the compliance voltage) and Vssh in a high power domain, and the NDACs are powered with power supplies Vcc and ground in a low power domain. VH may change during IPG operation, and Vssh preferably also changes with a fixed difference with respect to VH. Digital control signals to the PDACs are formed (and possibly converted into) the high power domain, and transistors used to build the PDACs are biased in the high power domain, and thus may also change with VH. This permits transistors in the PDACs and NDACs to be made from normal low-voltage logic transistors.
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公开(公告)号：US11697021B2
公开(公告)日：2023-07-11
申请号：US17140850
申请日：2021-01-04
CPC分类号： A61N1/36157 , A61N1/025 , A61N1/36125 , H03M1/72 , H03M1/745
摘要： An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.
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公开(公告)号：US20220233866A1
公开(公告)日：2022-07-28
申请号：US17597799
申请日：2020-08-04
摘要： Techniques for sensing neural responses such as Evoked Compound Action Potentials (ECAPs) in an implantable stimulator device are disclosed. A first therapeutic pulse phase is followed by a charge recovery phase that includes at least one high-impedance passive charge recovery duration. The ECAP is sensed during the high-impedance passive charge recovery duration. The time period of the passive charge recovery is lengthened and the high-impedance passive recharge duration entirely overlaps the ECAP (i.e., the neural response duration) at the sensing electrode.
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公开(公告)号：US10912942B2
公开(公告)日：2021-02-09
申请号：US16131809
申请日：2018-09-14
摘要： An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.
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公开(公告)号：US20190083797A1
公开(公告)日：2019-03-21
申请号：US16131824
申请日：2018-09-14
发明人： Pujitha Weerakoon , David M. Wagenbach , Philip L. Weiss , Goran N. Marnfeldt , Kiran K. Gururaj
IPC分类号： A61N1/375
摘要： An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.
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公开(公告)号：US20230347157A1
公开(公告)日：2023-11-02
申请号：US18348180
申请日：2023-07-06
发明人： Pujitha Weerakoon , David M. Wagenbach , Philip L. Weiss , Goran N. Marnfeldt , Kiran K. Gururaj
CPC分类号： A61N1/3758 , A61N1/36062 , A61N1/025
摘要： An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.
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