公开(公告)号：US07560688B2

公开(公告)日：2009-07-14

申请号：US11582198

申请日：2006-10-16

申请人： Brian H. Clowers ,  Herbert H. Hill, Jr. ,  Prabha Dwivedi ,  Matthew Pollard

发明人： Brian H. Clowers ,  Herbert H. Hill, Jr. ,  Prabha Dwivedi ,  Matthew Pollard

IPC分类号： H01J49/00

CPC分类号： H01J49/02 ,  G01N27/622 ,  H01J49/004

摘要： Particular aspects provide novel methods for analysis of ion populations, the methods comprising filtering and selecting an ion population using a low-field dual-gate ion mobility spectrometer comprising a drift tube, the spectrometer operating at a pressure of at least 100 Torr, to provide mobility-selected ions. Certain aspects comprise: (i) subsequently accumulating the low-field selected ions in an ion trap (e.g., an MS ion trap) and mass spectrometry analysis; (ii) introducing the low-field selected ions into a high-field ion mobility spectrometer for separating thereby (optionally followed by mass spectrometry); and (iii) introducing the low-field selected ions into an ion trap mass spectrometer, and subsequently into a second low-field ion mobility spectrometer (e.g., a non-dual gate spectrometer operating at less than about 100 Torr). Additional aspects provide novel apparatus and combination thereof for performing the disclosed methods.

摘要翻译： 具体方面提供用于分析离子群体的新方法，所述方法包括使用包含漂移管的低场双栅离子迁移谱仪来过滤和选择离子群，所述漂移管在至少100托的压力下操作，以提供 迁移率选择离子 某些方面包括：（i）随后在离子阱（例如，MS离子阱）中积聚低场选择的离子和质谱分析; （ii）将低场选择的离子引入用于分离的高场离子迁移谱仪（任选地随后进行质谱）; 和（iii）将低场选择的离子引入离子阱质谱仪中，随后进入第二低场离子迁移谱仪（例如，操作在小于约100托的非双栅光谱仪）。 另外的方面提供了用于执行所公开的方法的新颖的装置及其组合。

公开(公告)号：USPP13679P2

公开(公告)日：2003-03-25

申请号：US10142840

申请日：2002-05-10

申请人： Herbert H. Hill, Jr.

发明人： Herbert H. Hill, Jr.

IPC分类号： A01H500

CPC分类号： A01H5/02

摘要： A new and distinct cultivar of Guzmania plant named ‘Viola’, characterized by its upright and outwardly arching plant habit; medium green-colored foliage; inflorescences held upright and above foliage on strong scapes; branched inflorescences with showy red purple flower bracts; and long-lasting inflorescences that maintain good coloration for about two to three months.

摘要翻译： 一种新颖而独特的瓜斯马尼亚植物名为“中提琴”的植物，其特征是其直立和向外拱形的植物习性;中等绿色的叶子;花序在坚强的花纹上直立和高于叶子;枝叶花序与艳丽的紫色紫色花苞;长 保持良好的着色约2至3个月的花序。

公开(公告)号：USPP9670P

公开(公告)日：1996-10-22

申请号：US490973

申请日：1995-06-15

申请人： Herbert H. Hill, Jr.

发明人： Herbert H. Hill, Jr.

摘要： A new cultivar of Guzmania named 487-1 having miniature growth habit, and large, long-lasting, clean red-orange inflorescence with white tipped terminal bracts.

公开(公告)号：USPP8715P

公开(公告)日：1994-05-03

申请号：US17669

申请日：1993-02-10

申请人： Herbert H. Hill, Jr.

发明人： Herbert H. Hill, Jr.

摘要： A new cultivar of Guzmania named Guinn having bright red bract color which is not affected by heat, short and compact habit, a good tolerance to hard water, white flower bracts, and bracts which are relatively wide and extend more horizontally to provide a wide flowering structure.

公开(公告)号：USPP12081P1

公开(公告)日：2001-09-11

申请号：US09432079

申请日：1999-11-02

申请人： Herbert H. Hill, Jr.

发明人： Herbert H. Hill, Jr.

IPC分类号： A01H500

CPC分类号： A01H5/02

摘要： A Guzmania plant named ‘Symfonie Encore’ characterized by having variegated foliage that is reddish-pink at the sheath becoming cream-white at the apex of the leaf, large and long-lasting inflorescence with a distinctive yellow and red contrast, plants that are resistant to extremes in temperature (38-95° F.) and light intensity thereby tolerating a wide range of cultural conditions.

摘要翻译： 一种名为“Symfonie Encore”的古斯马尼亚植物，其特征在于具有斑点的叶子，在叶片的顶点具有红色粉红色，具有独特的黄色和红色对比度的大而持久的花序，具有抗性的植物 到极端温度（38-95°F）和光强度，从而可以忍受广泛的文化条件。

公开(公告)号：USPP10059P

公开(公告)日：1997-10-07

申请号：US651714

申请日：1996-05-22

申请人： Herbert H. Hill, Jr.

发明人： Herbert H. Hill, Jr.

摘要： A new cultivar of Guzmania named `Fireworks` having large star shaped, long lasting, dark red inflorescence with yellow-green terminal bracts and branch spikes. The foliage is durable and resistant to tip browning. Plants of `Fireworks` tolerate a wide range of cultural conditions and are easy to grow.

公开(公告)号：US11726102B2

公开(公告)日：2023-08-15

申请号：US16227554

申请日：2018-12-20

申请人： Herbert H. Hill, Jr. ,  Brian Clowers ,  Nicholas Lovrich

发明人： Herbert H. Hill, Jr. ,  Brian Clowers ,  Nicholas Lovrich

IPC分类号： G01N33/94 ,  G01N33/497 ,  G01N33/487 ,  G01N1/40 ,  G01N1/22 ,  G01N1/44 ,  G01N33/483 ,  A61B10/00 ,  G01N1/02

CPC分类号： G01N33/948 ,  A61B10/0051 ,  G01N1/2214 ,  G01N1/405 ,  G01N1/4022 ,  G01N1/44 ,  G01N33/483 ,  G01N33/487 ,  G01N33/4833 ,  G01N33/497 ,  A61B2010/0009 ,  G01N2001/022 ,  G01N2001/028 ,  G01N2001/2244 ,  G01N2033/4975

摘要： Disclosed herein are embodiments of methods for detecting the presence of and amount of drugs in a sample, particularly a particle sample obtained from a subject. In particular disclosed embodiments, the particle samples are skin particle samples, saliva particle samples, and/or mucous samples isolated from a subject and analyzed using thermal desorption methods combined with a selected detection method.

公开(公告)号：USPP12176P2

公开(公告)日：2001-10-30

申请号：US09586793

申请日：2000-06-05

申请人： Herbert H. Hill, Jr.

发明人： Herbert H. Hill, Jr.

IPC分类号： A01H500

CPC分类号： A01H5/02

摘要： A new Guzmania plant named ‘Anton’ particularly distinguished by its tall, purple bracted inflorescence. Plants of ‘Anton’ are of small to intermediate stature and are best grown in 10-cm to 12.5-cm pots. Plants of ‘Anton’ grow vigorously and produce exceptionally uniform crops. It tolerates a wide range of cultural conditions and is easy to grow.

摘要翻译： 一个新的Guzmania植物名为“安东”，其特征是其高紫紫色的花序，“安东”植物具有小到中等身材，最好种植在10厘米至12.5厘米的盆中。 “安东”植物大力生长，作物种类繁多，容忍广泛的文化条件，易生长。

公开(公告)号：USPP10787P

公开(公告)日：1999-02-09

申请号：US877956

申请日：1997-06-18

申请人： Herbert H. Hill, Jr.

发明人： Herbert H. Hill, Jr.

摘要： A new cultivar of Guzmania named `Olympic` having a very long lasting yellow and red bracted inflorescence. The inflorescence is clean appearing, and does not appear "flowered out" with age. The foliage is very dark green, shiny, durable and resistant to leaf spotting and tip browning. Plants of `Olympic` tolerate a wide range of cultural conditions and are easy to grow.

公开(公告)号：US4633083A

公开(公告)日：1986-12-30

申请号：US724514

申请日：1985-04-18

申请人： Fritz J. Knorr ,  Randy L. Eatherton ,  William F. Siems ,  Herbert H. Hill, Jr.

发明人： Fritz J. Knorr ,  Randy L. Eatherton ,  William F. Siems ,  Herbert H. Hill, Jr.

IPC分类号： G01N27/64 ,  B01D59/44

CPC分类号： G01N27/622

摘要： Methods and apparatus for time dispersive ion spectroscopy such as ion mobility spectroscopy. The methods include ionizing molecules of a sample and controllably admitting pulses of the resulting ions into a drift region. The drift region has an electric field therein which forces the admitted ions through the drift region. Ions emitted from the drift region during a gate open period simultaneous with the ion admission period are exclusively detected resulting in an ion detection signal. Data is recorded for the frequency rate at which the ion pulses are admitted to the drift region and the associated ion detector signal. The frequency of admitted ion pulses is scanned over a relevant range during which the ion admission period also varies. Data recorded for frequency and ion detection can be recorded and/or transformed such as by a Fourier transform to produce time dispersive spectra in the form of ion intensity or quantity as a function of the time period necessary for the ions to transit the drift region. Such spectra are useful in identifying constituents such as organic compounds contained in the sample. The methods and apparatus allow rapid analysis of samples and can be used to simultaneously analyze discharges from sample separation apparatus such as a capillary gas chromatograph.

摘要翻译： 用于时间分散离子光谱的方法和装置，如离子迁移谱。 所述方法包括样品的离子化分子和可控制地将所得离子的脉冲引入漂移区域。 漂移区域中具有电场，迫使允许的离子穿过漂移区域。 在离子入口期间同时进行闸门打开期间从漂移区域发射的离子被独占地检测，导致离子检测信号。 记录离子脉冲进入漂移区域的频率和相关离子检测器信号的数据。 允许离子脉冲的频率在相关范围内进行扫描，在此范围内离子入口周期也发生变化。 用于频率和离子检测记录的数据可以被记录和/或变换，例如通过傅里叶变换，以离子强度或数量的形式产生作​​为离子过渡漂移区所需时间的函数的时间色散谱。 这些光谱可用于鉴定样品中包含的有机化合物等成分。 该方法和装置允许对样品进行快速分析，并可用于同时分析样品分离装置如毛细管气相色谱仪的放电。