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    Medical device with tensionably attached remodelable material
    5.
    发明授权
    Medical device with tensionably attached remodelable material 有权
    具有可张力连接的可重塑材料的医疗装置

    公开(公告)号：US08128682B2

    公开(公告)日：2012-03-06

    申请号：US12777947

    申请日：2010-05-11

    申请人： Brian C. Case ,  Jacob A. Flagle ,  Ram H. Paul, Jr. ,  Sean D. Chambers

    发明人： Brian C. Case ,  Jacob A. Flagle ,  Ram H. Paul, Jr. ,  Sean D. Chambers

    IPC分类号： A61F2/82

    CPC分类号： A61F2/2418 ,  A61F2/07 ,  A61F2/2475 ,  A61F2/86 ,  A61F2/90 ,  A61F2002/075 ,  A61F2210/0004 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0071 ,  A61F2250/0018 ,  A61F2250/0031 ,  A61F2250/0071

    摘要： Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device includes a support frame having struts and a weakened frame portion, and a remodelable material tensionably attached to the support frame. The weakened frame portion has a first configuration in which the support frame has a first outward radial force and a second configuration in which the support frame has a second, lesser outward radial force. The remodelable material restricts expansion of the frame from a radially compressed configuration to a radially expanded configuration when the weakened frame portion is in the first configuration. The remodelable material can form one or more valve leaflets adapted to regulate fluid flow in a body vessel, such as a vein.

    摘要翻译： 提供了用于植入体内的医疗装置及其使用和制造方法。 医疗装置包括具有支柱和弱化框架部分的支撑框架和可张紧地附接到支撑框架的可重塑材料。 弱化的框架部分具有第一构造，其中支撑框架具有第一向外径向力和第二构造，其中支撑框架具有第二较小的向外径向力。 当变弱的框架部分处于第一构型时，可重塑材料将框架从径向压缩构型扩展到径向扩张构型。 可重塑材料可以形成适于调节诸如静脉的体内血管中的流体流动的一个或多个瓣膜小叶。

    Methods, systems and devices for the delivery of endoluminal prostheses
    6.
    发明授权
    Methods, systems and devices for the delivery of endoluminal prostheses 有权
    用于输送腔内假体的方法，系统和装置

    公开(公告)号：US09307995B2

    公开(公告)日：2016-04-12

    申请号：US11763773

    申请日：2007-06-15

    申请人： Ram H. Paul ,  Brian C. Case ,  Jacob A. Flagle

    发明人： Ram H. Paul ,  Brian C. Case ,  Jacob A. Flagle

    IPC分类号： A61B17/08 ,  A61B17/12 ,  A61B17/00 ,  A61B17/22

    CPC分类号： A61B17/12031 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12181 ,  A61B17/1219 ,  A61B2017/00778 ,  A61B2017/00867 ,  A61B2017/00898 ,  A61B2017/1205 ,  A61B2017/22038

    摘要： Described are devices, methods, and systems for achieving occlusion of vascular vessels. Further described are certain reduced or low profile procedures and devices for the percutaneous occlusion of the saphenous vein, such as in the treatment of a varicose vein condition caused by venous reflux. Devices and procedures can involve an endoluminal delivery device having an atraumatic distal end, that is advancable through a vascular vessel, and an occlusion device received on the endoluminal delivery device. The endoluminal delivery device can have one or more adaptations for releasably receiving the occlusion device. The occlusion device can include a sponge form material. The occlusion device can include a remodelable material or a synthetic material. The occlusion device can include an anchor.

    摘要翻译： 描述了用于实现血管血管闭塞的装置，方法和系统。 进一步描述了用于经皮闭塞隐静脉的某些缩减或低调程序和装置，例如用于治疗由静脉回流引起的静脉曲张病症。 装置和程序可以包括具有无创损伤远端的腔内输送装置，其可通过血管容器和通过内腔输送装置接收的闭塞装置。 腔内输送装置可具有用于可释放地接收闭塞装置的一种或多种适应。 闭塞装置可以包括海绵形式的材料。 闭塞装置可包括可重塑材料或合成材料。 遮挡装置可以包括锚固件。

    Valvulotome device and method
    7.
    发明授权
    Valvulotome device and method 有权
    瓣膜切除装置及方法

    公开(公告)号：US08398663B2

    公开(公告)日：2013-03-19

    申请号：US12781300

    申请日：2010-05-17

    申请人： Ram H. Paul, Jr. ,  Brian C. Case ,  Jacob A. Flagle

    发明人： Ram H. Paul, Jr. ,  Brian C. Case ,  Jacob A. Flagle

    IPC分类号： A61B17/22

    CPC分类号： A61B17/3207 ,  A61B17/320725 ,  A61B2017/22097

    摘要： Valvulotome devices and methods are provided. Valvulotome devices include one or more valvulotome arms that have a u-shaped curved body with opposing arms and a base portion that extends between the arms. The valvulotome arm defines a notch open at one end on one of the arms and extending into the base portion of the u-shaped curved body. The notch defines an angled surface that provides a cutting edge. Methods of making valvulotome devices are also described.

    摘要翻译： 提供瓣膜切除装置和方法。 瓣膜切开装置包括一个或多个瓣膜切开臂，其具有带相对臂的u形弯曲体和在臂之间延伸的基部。 瓣膜切开臂限定了在一个臂上的一端处开口并且延伸到U形弯曲体的基部中的凹口。 切口限定了提供切削刃的成角度的表面。 还描述了制造瓣膜切开术装置的方法。

    VALVULOTOME DEVICE AND METHOD
    8.
    发明申请
    VALVULOTOME DEVICE AND METHOD 有权
    VALVULOTOME设备和方法

    公开(公告)号：US20100286719A1

    公开(公告)日：2010-11-11

    申请号：US12781300

    申请日：2010-05-17

    申请人： Ram H. Paul ,  Brian C. Case ,  Jacob A. Flagle

    发明人： Ram H. Paul ,  Brian C. Case ,  Jacob A. Flagle

    IPC分类号： A61B17/22

    CPC分类号： A61B17/3207 ,  A61B17/320725 ,  A61B2017/22097

    摘要： Valvulotome devices and methods are provided. Valvulotome devices include one or more valvulotome arms that have a u-shaped curved body with opposing arms and a base portion that extends between the arms. The valvulotome arm defines a notch open at one end on one of the arms and extending into the base portion of the u-shaped curved body. The notch defines an angled surface that provides a cutting edge. Methods of making valvulotome devices are also described.

    摘要翻译： 提供瓣膜切除装置和方法。 瓣膜切开装置包括一个或多个瓣膜切开臂，其具有带相对臂的u形弯曲体和在臂之间延伸的基部。 瓣膜切开臂限定了在一个臂上的一端处开口并且延伸到U形弯曲体的基部中的凹口。 切口限定了提供切削刃的成角度的表面。 还描述了制造瓣膜切开术装置的方法。

    MEDICAL DEVICE WITH TENSIONABLY ATTACHED REMODELABLE MATERIAL
    9.
    发明申请
    MEDICAL DEVICE WITH TENSIONABLY ATTACHED REMODELABLE MATERIAL 有权
    具有可张紧连接的可重复材料的医疗装置

    公开(公告)号：US20100280586A1

    公开(公告)日：2010-11-04

    申请号：US12777947

    申请日：2010-05-11

    申请人： Brian C. Case ,  Jacob A. Flagle ,  Ram H. Paul, JR. ,  Sean D. Chambers

    发明人： Brian C. Case ,  Jacob A. Flagle ,  Ram H. Paul, JR. ,  Sean D. Chambers

    IPC分类号： A61F2/82

    CPC分类号： A61F2/2418 ,  A61F2/07 ,  A61F2/2475 ,  A61F2/86 ,  A61F2/90 ,  A61F2002/075 ,  A61F2210/0004 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0071 ,  A61F2250/0018 ,  A61F2250/0031 ,  A61F2250/0071

    摘要： Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device includes a support frame having struts and a weakened frame portion, and a remodelable material tensionably attached to the support frame. The weakened frame portion has a first configuration in which the support frame has a first outward radial force and a second configuration in which the support frame has a second, lesser outward radial force. The remodellable material restricts expansion of the frame from a radially compressed configuration to a radially expanded configuration when the weakened frame portion is in the first configuration. The remodelable material can form one or more valve leaflets adapted to regulate fluid flow in a body vessel, such as a vein.

    摘要翻译： 提供了用于植入体内的医疗装置及其使用和制造方法。 医疗装置包括具有支柱和弱化框架部分的支撑框架和可张紧地附接到支撑框架的可重塑材料。 弱化的框架部分具有第一构造，其中支撑框架具有第一向外径向力和第二构造，其中支撑框架具有第二较小的向外径向力。 当减弱的框架部分处于第一构造时，可重构材料限制框架从径向压缩构型到径向膨胀构型的膨胀。 可重塑材料可以形成适于调节诸如静脉的体内血管中的流体流动的一个或多个瓣膜小叶。

    Inflatable occlusion devices, methods, and systems
    10.
    发明授权
    Inflatable occlusion devices, methods, and systems 有权
    充气闭塞装置，方法和系统

    公开(公告)号：US07744621B2

    公开(公告)日：2010-06-29

    申请号：US11294998

    申请日：2005-12-06

    申请人： Ram H. Paul ,  Jacob A. Flagle ,  Brian C. Case

    发明人： Ram H. Paul ,  Jacob A. Flagle ,  Brian C. Case

    IPC分类号： A61M29/00

    CPC分类号： A61L29/005 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/1219 ,  A61B2017/1205

    摘要： Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the deployment and filling of an inflatable occlusion device via a percutaneous procedure, so as to occlude or obliterate a portion of a vascular vessel.

    摘要翻译： 描述了用于实现血管血管阻塞的装置，方法和系统。 经皮手术可用于闭塞和闭塞较大的隐静脉，例如用于治疗由静脉回流引起的静脉曲张病变。 某些实施方案包括经由经皮程序展开和填充可充气闭塞装置，从而封闭或消除血管容器的一部分。