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    Methods and apparatuses for blood component separation
    5.
    发明授权
    Methods and apparatuses for blood component separation 有权
    血液成分分离方法和装置

    公开(公告)号：US07166217B2

    公开(公告)日：2007-01-23

    申请号：US10648559

    申请日：2003-08-25

    申请人： Brian M. Holmes ,  J-P Hagström ,  Per-Olov Lundberg ,  Geert Van Waeg ,  Peter Nordgren

    发明人： Brian M. Holmes ,  J-P Hagström ,  Per-Olov Lundberg ,  Geert Van Waeg ,  Peter Nordgren

    IPC分类号： B04B1/00 ,  A61M1/36

    CPC分类号： B04B13/00 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/025 ,  A61M1/26 ,  A61M1/262 ,  A61M1/3633 ,  A61M1/3639 ,  A61M1/3641 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/3698 ,  A61M2205/331 ,  B04B5/0428 ,  B04B5/0442 ,  B04B2005/045 ,  B04B2005/0478 ,  B04B2013/006

    摘要： A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the separation space of the rotor and first and second collection containers connected to the separation container by a first and a second tubes. The tubes are adapted to be disposed in operative relationship with the valve members so that flow through the tubes may be controlled thereby. Three components of the composite fluid may be separated therefrom by the present system and two components may be moved to the collection containers. The container set may further include a third collection container connected to the separation container by a tube, and a third component may thus be moved to this third container.

    摘要翻译： 一种将复合流体分离成其组成部分的系统，包括：具有分离空间的转子和设置在其上的至少两个阀构件的离心机和具有适于设置在转子的分离空间中的分离容器的容器组 以及通过第一和第二管连接到分离容器的第一和第二收集容器。 管适于与阀构件成可操作的关系，从而可以控制通过管的流动。 复合流体的三个组分可以通过本系统与其分离，并且两个组分可以移动到收集容器中。 容器组还可以包括通过管连接到分离容器的第三收集容器，并且因此第三组分可以移动到第三容器。

    Method for separating a volume of composite liquid into at least two components
    6.
    发明授权
    Method for separating a volume of composite liquid into at least two components 有权
    将复合液体的体积分离成至少两个组分的方法

    公开(公告)号：US07648639B2

    公开(公告)日：2010-01-19

    申请号：US11956696

    申请日：2007-12-14

    申请人： Brian M. Holmes ,  Peter Pihlstedt ,  Geert Van Waeg

    发明人： Brian M. Holmes ,  Peter Pihlstedt ,  Geert Van Waeg

    IPC分类号： B04B1/00 ,  B04B3/00

    CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/3696 ,  A61M1/3698 ,  A61M2205/331 ,  B01D21/262 ,  B01D2221/10 ,  B04B5/0428 ,  B04B5/0442 ,  B04B13/00 ,  B04B2013/006

    摘要： A method for separating a volume of a composite liquid into at least a first component and a second component is performed in a centrifuge cooperating with a separation bag containing the volume of composite liquid. The separation bag is connected to at least a first component bag and a second component bag. The separation bag is spun so as to centrifuge the volume of composite liquid and cause the sedimentation of the at least first and second components. When the at least first and second components have sedimented, the first component is transferred at least one first transfer flow rate into the first component bag. When the first component has been transferred into the first component bag, the second component is transferred into the intermediate component bag at least one second transfer flow rate that is different from the at least one first transfer flow rate.

    摘要翻译： 在与包含复合液体体积的分离袋配合的离心机中进行将复合液体的体积分离成至少第一成分和第二成分的方法。 分离袋连接到至少第一组分袋和第二组分袋。 旋转分离袋以离心复合液体的体积并引起至少第一和第二组分的沉降。 当至少第一和第二组分沉淀时，第一组分将至少一个第一转移流速转移到第一组分袋中。 当第一组分已被转移到第一组分袋中时，将第二组分转移到中间组分袋中至少一个不同于至少一个第一转移流速的第二转移流速。

    Method for optimizing spin time in a centrifuge apparatus for biologic fluid
    8.
    发明授权
    Method for optimizing spin time in a centrifuge apparatus for biologic fluid 有权
    用于在生物液体的离心机中优化旋转时间的方法

    公开(公告)号：US08900112B2

    公开(公告)日：2014-12-02

    申请号：US13176466

    申请日：2011-07-05

    申请人： Brian M. Holmes ,  Briden Ray Stanton ,  Geert Van Waeg ,  Mary Langley

    发明人： Brian M. Holmes ,  Briden Ray Stanton ,  Geert Van Waeg ,  Robert Langley

    IPC分类号： B01D21/26 ,  B04B5/04 ,  A61M1/36 ,  B04B13/00

    CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/3696 ,  A61M1/3698 ,  B04B5/0428 ,  B04B2013/006

    摘要： A method for controlling a centrifuge blood component separation system for separating components of a blood product, the separation system comprising a centrifuge and a separation bag and at least one transfer bag. The method comprises selecting a nominal hematocrit value such that an actual hematocrit value is expected to be less than said nominal hematocrit; centrifuging a separation bag containing a volume of composite liquid so as to cause the sedimentation of at least a first component and a second component; transferring some of the first component to a first transfer bag; detecting time of passage of a red blood cell interface at a pre-selected location in the separation bag; and adjusting a predicted processing time based on the time of passage of the red blood cell interface.

    摘要翻译： 一种用于控制用于分离血液制品的组分的离心机血液成分分离系统的方法，所述分离系统包括离心机和分离袋以及至少一个转运袋。 该方法包括选择名义血细胞比容值，使得实际血细胞比容值预期小于所述标称血细胞比容; 将含有一定体积的复合液体的分离袋离心，以至少使第一组分和第二组分沉淀; 将一些第一组分转移到第一转运袋中; 检测分离袋中预选位置处红细胞界面通过的时间; 以及基于红细胞接口的通过时间来调整预测的处理时间。