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1.发明授权System and method for collecting plasma protein fractions from separated blood components 有权用于从分离的血液成分收集血浆蛋白质级分的系统和方法公开(公告)号：US08202240B2
公开(公告)日：2012-06-19
申请号：US12429325
申请日：2009-04-24
CPC分类号： A61M1/3496 , A61M2205/128
摘要： Method and apparatus for separating plasma from blood in a membrane separator and further separator the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the membrane separator to receive the separated plasma.
摘要翻译： 用于在膜分离器中从血液中分离血浆的方法和装置，并且将分离的血浆进一步将流体连接到膜分离器的血浆分离器中的所需血浆蛋白分离，以接收分离的血浆。
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公开(公告)号：US07708889B2
公开(公告)日：2010-05-04
申请号：US12359738
申请日：2009-01-26
申请人： Niclas Högberg , Emanuel Hällgren , Peter Pihlstedt , Brian M. Holmes , Lars Persson , Lars Strandberg , Geert Van Waeg , Frank Corbin, III
发明人： Niclas Högberg , Emanuel Hällgren , Peter Pihlstedt , Brian M. Holmes , Lars Persson , Lars Strandberg , Geert Van Waeg , Frank Corbin, III
CPC分类号： B04B13/00 , A61M1/0209 , A61M1/0218 , A61M1/025 , A61M1/26 , A61M1/262 , A61M1/3633 , A61M1/3639 , A61M1/3641 , A61M1/3693 , A61M1/3696 , A61M1/3698 , A61M2205/331 , B04B5/0428 , B04B5/0442 , B04B2005/045 , B04B2005/0478 , B04B2013/006
摘要： A method used in connection with processing of blood components, wherein blood products are then filtered via a filter rotating along with a centrifuge rotor and the sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products.
摘要翻译： 一种与血液成分的处理有关的方法，其中血液产物然后通过与离心机转子一起旋转的过滤器过滤，并且感测到的压力可用于控制血液制品的泵送和/或结合确定 与血液制品相关联的界面的位置。
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公开(公告)号：US20090127206A1
公开(公告)日：2009-05-21
申请号：US12359738
申请日：2009-01-26
申请人： Niclas HOGBERG , Emanuel HALLGREN , Peter PIHLSTEDT , Brian M. HOLMES , Lars PERSSON , Lars STRANDBERG , Geert VAN WAEG , Frank CORBIN, III
发明人： Niclas HOGBERG , Emanuel HALLGREN , Peter PIHLSTEDT , Brian M. HOLMES , Lars PERSSON , Lars STRANDBERG , Geert VAN WAEG , Frank CORBIN, III
CPC分类号： B04B13/00 , A61M1/0209 , A61M1/0218 , A61M1/025 , A61M1/26 , A61M1/262 , A61M1/3633 , A61M1/3639 , A61M1/3641 , A61M1/3693 , A61M1/3696 , A61M1/3698 , A61M2205/331 , B04B5/0428 , B04B5/0442 , B04B2005/045 , B04B2005/0478 , B04B2013/006
摘要： A method used in connection with processing of blood components, wherein blood products are then filtered via a filter rotating along with a centrifuge rotor and the sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products.
摘要翻译： 一种与血液成分的处理有关的方法，其中血液产物然后通过与离心机转子一起旋转的过滤器过滤，并且感测到的压力可用于控制血液制品的泵送和/或结合确定 与血液制品相关联的界面的位置。
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公开(公告)号：US06179801B2
公开(公告)日：2001-01-30
申请号：US09071293
申请日：1998-01-21
IPC分类号： A61M3700
CPC分类号： B04B5/0442 , A61M1/3624 , A61M1/3639 , A61M1/3641 , A61M1/3652 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2205/123 , A61M2205/125 , A61M2205/128 , A61M2205/14 , A61M2205/505 , B04B9/08 , B04B2005/045
摘要： An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
摘要翻译： 公开了一种体外血液处理系统，其包括各种新颖的组分，并且可以根据各种新颖的方法进行操作。 例如，该系统包括图形操作员界面，其指导操作者通过单采程序的各个方面。 此外，该系统还包括与将血液处理容器装载到血液处理通道中并且在完成手术之后移除血液处理通道相关的各种特征。 此外，该系统还包括与准备该过程一起使用至少部分单采血液系统的血液灌注相关的各种特征。 此外，该系统包括增强单采血液系统性能的各种特征，包括血液处理容器和血液处理容器之间的相互关系以及该程序的高填充因子的利用。
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公开(公告)号：US5910252A
公开(公告)日：1999-06-08
申请号：US17571
申请日：1993-02-12
申请人： Lori A. Truitt , Frank Corbin, III , Donn D. Lobdell , Douglas P. Miller , Keith Manica , George J. Eilers , Steven H. Johnson , Lawrence L. Leppert
发明人： Lori A. Truitt , Frank Corbin, III , Donn D. Lobdell , Douglas P. Miller , Keith Manica , George J. Eilers , Steven H. Johnson , Lawrence L. Leppert
IPC分类号： A61M1/14 , A61M1/16 , A61M1/34 , A61M1/36 , C07K14/47 , C07K16/40 , C12N9/64 , G01N33/573 , G01N33/68 , B01D61/22 , B01D61/00 , B01D61/32
CPC分类号： A61M1/16 , A61M1/1643 , A61M1/3431 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M1/3468 , A61M1/3643 , C07K14/4711 , C07K16/40 , C12N9/6421 , G01N33/573 , G01N33/6896 , A61M1/3413 , A61M2205/12 , A61M2205/13 , A61M2205/15 , A61M2205/18 , A61M2205/3393 , A61M2205/505 , A61M2209/084 , Y10S210/929
摘要： Blood from a patient is treated extracorporeally by any selected one of a plurality of predetermined treatments. Each of the treatments involves the flow of blood from the patient into a primary chamber of a filtration unit, past a semipermeable membrane located in the filtration unit which separates the primary chamber from a secondary chamber of the filtration unit, out the filtration unit and back to the patient. A replacement fluid is selectively and controllably added to the blood, as required for the selected treatment. A secondary fluid is controllably and selectively introduced into the secondary chamber of the filtration unit for controllably collecting material passing across the semipermeable membrane from the blood or for supplying material to pass across the semipermeable membrane into the blood as required for the selected treatment. Materials are removed from the secondary chamber and collected in accordance with the selected treatment. Upon selection of one of the plurality of extracorporeal blood treatments available, the rates of blood flow, fluid flow and fluid collection during the extracorporeal treatment are automatically determined, established and monitored in accordance with the selected treatment. An apparatus which automatically performs and monitors the selected treatment is also described.
摘要翻译： 来自患者的血液通过多种预定治疗中的任意选择进行体外治疗。 每个处理涉及从患者流入到过滤单元的主室中的血液，通过位于过滤单元中的半透膜，该过滤单元将主室与过滤单元的次室分离出过滤单元和背部 给病人 根据所选择的处理的要求，将替代液体选择性地和可控地添加到血液中。 二次流体被可控地和选择性地引入过滤单元的次级室中，用于可控地从血液中收集穿过半透膜的材料，或者用于供应材料以通过所选择的处理所需的半透膜进入血液。 根据所选择的处理将材料从次级室除去并收集。 在选择可用的多种体外血液处理中的一种时，根据所选择的治疗自动确定，建立和监测体外治疗期间的血流量，流体流量和流体收集率。 还描述了自动执行和监视所选择的处理的装置。
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6.发明授权
公开(公告)号：US5520218A
公开(公告)日：1996-05-28
申请号：US257653
申请日：1994-06-09
IPC分类号： A61M5/14 , B29C57/10 , B29C65/00 , B29C65/04 , B29C65/74 , B29L23/00 , B65B51/10 , F16L55/10
CPC分类号： B29C65/04 , B29C65/743 , B29C66/1122 , B29C66/4312 , B29C66/73921 , B29C66/8122 , B29C66/81263 , B29C66/81422 , B29C66/8187 , B29C66/8322 , B29C66/857 , B29C66/8614 , B29C57/10 , B29C66/71 , B29C66/81871 , B29L2023/007 , B29L2031/753 , Y10S128/24 , Y10S604/905
摘要： A tubing set includes at least one fluid conveying tube. The fluid conveying tube has a predetermined outside diameter, and is formed of a material adapted to be dielectrically heated at a sealing location. The insulating sleeve has an inside dimension at least as large as the outside diameter of the fluid conveying tube. The tubular insulating sleeve is positioned in a substantially coaxial relationship with the fluid conveying tube at the sealing location, and has a wall with thickness which insulates the fluid conveying tube to permit sealing the fluid conveying tube, and forming a thin, easily tearable web, by the application of the radio frequency dielectric heating.
摘要翻译： 管组包括至少一个流体输送管。 流体输送管具有预定的外径，并且由适于在密封位置进行介电加热的材料形成。 绝缘套筒具有至少与流体输送管的外径一样大的内部尺寸。 管状绝缘套管在密封位置处与流体输送管基本上同轴的关系定位，并且具有厚度的壁，该壁具有使流体输送管绝缘以允许密封流体输送管，并且形成薄的易撕层的腹板， 通过应用射频电介质加热。
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公开(公告)号：US20120145619A1
公开(公告)日：2012-06-14
申请号：US13400811
申请日：2012-02-21
CPC分类号： A61M1/36 , A61M1/3496 , A61M1/3696 , A61M1/38 , A61M2202/0415 , A61M2202/07 , A61M2205/12
摘要： An integrated pre-connected apheresis disposable set for separating plasma from blood in a separation vessel and further separating the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the separation vessel to receive the separated plasma.
摘要翻译： 一种用于在分离容器中分离等离子体与血液的集成的预连接的单采血浆置换组件，并且将分离的血浆进一步在流体连接到分离容器的等离子体分离器中分离成期望的血浆蛋白质以接收分离的血浆。
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8.发明授权System and method for collecting plasma protein fractions from separated blood components 有权用于从分离的血液成分收集血浆蛋白质级分的系统和方法公开(公告)号：US08123713B2
公开(公告)日：2012-02-28
申请号：US12429266
申请日：2009-04-24
CPC分类号： A61M1/36 , A61M1/3496 , A61M1/3696 , A61M1/38 , A61M2202/0415 , A61M2202/07 , A61M2205/12
摘要： Method and apparatus for separating plasma from blood in a separation vessel and further separator the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the separation vessel to receive the separated plasma.
摘要翻译： 用于在分离容器中从血液中分离血浆的方法和装置，并且将分离的血浆进一步将流体连接到分离容器的血浆分离器中的所需血浆蛋白分离，以接收分离的血浆。
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9.发明申请System and Method for Collecting Plasma Protein Fractions from Separated Blood Components 有权用于从分离的血液成分收集血浆蛋白质级分的系统和方法公开(公告)号：US20100042038A1
公开(公告)日：2010-02-18
申请号：US12429325
申请日：2009-04-24
CPC分类号： A61M1/3496 , A61M2205/128
摘要： Method and apparatus for separating plasma from blood in a membrane separator and further separator the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the membrane separator to receive the separated plasma.
摘要翻译： 用于在膜分离器中从血液中分离血浆的方法和装置，并且将分离的血浆进一步将流体连接到膜分离器的血浆分离器中的所需血浆蛋白分离，以接收分离的血浆。
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公开(公告)号：US06231537B1
公开(公告)日：2001-05-15
申请号：US09010077
申请日：1998-01-21
IPC分类号： A61M3700
CPC分类号： B04B5/0442 , A61M1/3624 , A61M1/3639 , A61M1/3641 , A61M1/3652 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2205/123 , A61M2205/125 , A61M2205/128 , A61M2205/14 , A61M2205/505 , B04B9/08 , B04B2005/045
摘要： An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
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