公开(公告)号：US08920489B2

公开(公告)日：2014-12-30

申请号：US13196492

申请日：2011-08-02

申请人： Brian P. Baillargeon ,  Ramesh Marrey ,  John Kenneth Ryder ,  Randy David B Grishaber ,  Ryan R. Donovan

发明人： Brian P. Baillargeon ,  Ramesh Marrey ,  John Kenneth Ryder ,  Randy David B Grishaber ,  Ryan R. Donovan

IPC分类号： A61F2/06 ,  A61F2/915 ,  A61F2/91 ,  A61F2/88

CPC分类号： A61F2/915 ,  A61F2/88 ,  A61F2/91 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2250/0068

摘要： The present invention relates to tissue-supporting medical devices and drug delivery systems, and more particularly to tubular flexible stents that are implanted within a body lumen of a living animal or human to support the organ, maintain patency and/or deliver drugs or agents. The tubular flexible stent has a cylindrical shape defining a longitudinal axis and includes a helical section having of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band. The band is wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings. At least one connector member extends between adjacent windings.

摘要翻译： 本发明涉及组织支撑医疗装置和药物递送系统，更具体地涉及植入活的动物或人体的体腔中以支持器官，维持开放和/或递送药物或药剂的管状柔性支架。 管状柔性支架具有限定纵向轴线的圆柱形形状，并且包括具有多个纵向取向的支柱构件的螺旋部分和连接周向相邻的支柱构件以形成带的多个周向定向的铰链构件。 该带围绕纵向轴线以大致螺旋状的方式缠绕以形成多个螺旋绕组。 至少一个连接器构件在相邻绕组之间延伸。

公开(公告)号：US20120029623A1

公开(公告)日：2012-02-02

申请号：US13196492

申请日：2011-08-02

申请人： BRIAN P. BAILLARGEON ,  Ramesh Marrey ,  John Kenneth Ryder ,  Randy David B. Grishaber ,  Ryan R. Donovan

发明人： BRIAN P. BAILLARGEON ,  Ramesh Marrey ,  John Kenneth Ryder ,  Randy David B. Grishaber ,  Ryan R. Donovan

IPC分类号： A61F2/82

CPC分类号： A61F2/915 ,  A61F2/88 ,  A61F2/91 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2250/0068

摘要： The present invention relates to tissue-supporting medical devices and drug delivery systems, and more particularly to tubular flexible stents that are implanted within a body lumen of a living animal or human to support the organ, maintain patency and/or deliver drugs or agents. The tubular flexible stent has a cylindrical shape defining a longitudinal axis and includes a helical section having of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band. The band is wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings. At least one connector member extends between adjacent windings.

摘要翻译： 本发明涉及组织支撑医疗装置和药物递送系统，更具体地涉及植入活的动物或人体的体腔中以支持器官，维持开放和/或递送药物或药剂的管状柔性支架。 管状柔性支架具有限定纵向轴线的圆柱形形状，并且包括具有多个纵向取向的支柱构件的螺旋部分和连接周向相邻的支柱构件以形成带的多个周向定向的铰链构件。 该带围绕纵向轴线以大致螺旋状的方式缠绕以形成多个螺旋绕组。 至少一个连接器构件在相邻绕组之间延伸。

公开(公告)号：US20120029622A1

公开(公告)日：2012-02-02

申请号：US13196475

申请日：2011-08-02

申请人： BRIAN P. BAILLARGEON ,  Ramesh Marrey

发明人： BRIAN P. BAILLARGEON ,  Ramesh Marrey

IPC分类号： A61F2/82

CPC分类号： A61F2/915 ,  A61F2/885 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2230/0054 ,  A61F2250/0014 ,  A61F2250/0068

摘要： The present invention relates to tubular stents that are implanted within a body lumen. The stent has a cylindrical shape defining a longitudinal axis and includes a proximal helical section, a distal helical section and an intermediate ring section there between. Each of the proximal and distal helical sections has of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band, the band being wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings, wherein the distal helical section is wound about the longitudinal axis in the opposite direction from the proximal helical section. The intermediate ring section includes a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form an endless ring.

摘要翻译： 本发明涉及植入体腔内的管状支架。 支架具有限定纵向轴线的圆柱形形状，并且包括近端螺旋部分，远端螺旋部分和中间环部分。 近端螺旋段和远端螺旋段中的每一个具有多个纵向取向的支柱构件和多个周向定向的铰链构件，其连接周向相邻的支柱构件以形成带，该带围绕纵向轴线以基本上螺旋的方式缠绕以形成 多个螺旋绕组，其中所述远侧螺旋部分围绕所述纵向轴线在与所述近端螺旋部分相反的方向上缠绕。 中间环段包括多个纵向取向的支柱构件和多个周向定向的铰链构件，其连接周向相邻的支柱构件以形成环形环。

公开(公告)号：US08961590B2

公开(公告)日：2015-02-24

申请号：US13196475

申请日：2011-08-02

申请人： Brian P. Baillargeon ,  Ramesh Marrey

发明人： Brian P. Baillargeon ,  Ramesh Marrey

IPC分类号： A61F2/06 ,  A61F2/915 ,  A61F2/88

CPC分类号： A61F2/915 ,  A61F2/885 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2230/0054 ,  A61F2250/0014 ,  A61F2250/0068

摘要： The present invention relates to tubular stents that are implanted within a body lumen. The stent has a cylindrical shape defining a longitudinal axis and includes a proximal helical section, a distal helical section and an intermediate ring section there between. Each of the proximal and distal helical sections has of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band, the band being wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings, wherein the distal helical section is wound about the longitudinal axis in the opposite direction from the proximal helical section. The intermediate ring section includes a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form an endless ring.

摘要翻译： 本发明涉及植入体腔内的管状支架。 支架具有限定纵向轴线的圆柱形形状，并且包括近端螺旋部分，远端螺旋部分和中间环部分。 近端螺旋段和远端螺旋段中的每一个具有多个纵向取向的支柱构件和多个周向定向的铰链构件，其连接周向相邻的支柱构件以形成带，该带围绕纵向轴线以基本上螺旋的方式缠绕以形成 多个螺旋绕组，其中所述远侧螺旋部分围绕所述纵向轴线在与所述近端螺旋部分相反的方向上缠绕。 中间环段包括多个纵向取向的支柱构件和多个周向定向的铰链构件，其连接周向相邻的支柱构件以形成环形环。

公开(公告)号：US08551154B2

公开(公告)日：2013-10-08

申请号：US11172527

申请日：2005-06-30

申请人： Robert Burgermeister ,  Randy Grishaber ,  Ramesh Marrey ,  Jin Park ,  Mathew Krever ,  David Overaker

发明人： Robert Burgermeister ,  Randy Grishaber ,  Ramesh Marrey ,  Jin Park ,  Mathew Krever ,  David Overaker

IPC分类号： A61F2/06

CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91508 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2002/91583 ,  A61F2250/0036

摘要： This invention relates generally to expandable intraluminal medical devices for use within a body passageway or duct, and more particularly to an optimized stent having asymmetrical strut and loop members, wherein at least one pair adjacent radial strut members have unequal axial lengths.

摘要翻译： 本发明一般涉及用于体内通道或管道内的可扩张的管腔内医疗装置，更具体地涉及具有不对称支柱和环构件的优化支架，其中至少一对相邻的径向支柱构件具有不等轴向长度。

公开(公告)号：US09393135B2

公开(公告)日：2016-07-19

申请号：US11747500

申请日：2007-05-11

申请人： Robert Burgermeister ,  Ramesh Marrey ,  Vipul Bhupendra Dave ,  David Overaker ,  Joseph H. Contiliano ,  Qiang Zhang

发明人： Robert Burgermeister ,  Ramesh Marrey ,  Vipul Bhupendra Dave ,  David Overaker ,  Joseph H. Contiliano ,  Qiang Zhang

IPC分类号： A61F2/915 ,  A61L31/04 ,  A61L31/16 ,  A61L31/18 ,  A61F2/82

CPC分类号： A61F2/915 ,  A61F2/82 ,  A61F2002/825 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2250/0018 ,  A61F2250/0028 ,  A61F2250/0029 ,  A61F2250/0036 ,  A61F2250/0062 ,  A61F2250/0067 ,  A61F2250/0098 ,  A61L31/04 ,  A61L31/16 ,  A61L31/18 ,  A61L2300/416

摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics. The stent has a plurality of hoop components interconnected by a plurality of flexible connectors. The hoop components are formed as a continuous series of substantially longitudinally or axially oriented radial strut members and alternating substantially circumferentially oriented radial arc members. The geometry of the struts and arcs is such that when the stent is expanded, it has very high strains within a relatively small region. This strain localization results in what is often referred to as “hinging”, where the hinge is the small region within which the strains are very high.

摘要翻译： 生物相容性材料可以配置成任何数量的可植入医疗装置，包括腔内支架。 可以使用聚合材料来制造包括支架在内的任何这些装置。 支架可以是球囊扩张或自扩张。 聚合物材料可以包括添加剂如药物或其他生物活性剂以及不透射线剂。 通过聚合物的优先机械变形，聚合物链可以被取向以获得某些所需的性能特征。 支架具有通过多个柔性连接器互连的多个环部件。 环形部件形成为基本纵向或轴向定向的径向支柱构件和交替的基本上周向定向的径向弧形构件的连续系列。 支柱和弧的几何形状使得当支架膨胀时，其在相对小的区域内具有非常高的应变。 这种应变定位导致通常被称为“铰接”，其中铰链是应变非常高的小区域。

公开(公告)号：US20100217380A1

公开(公告)日：2010-08-26

申请号：US12698717

申请日：2010-02-02

申请人： Ryan Donovan ,  John F. Shanley ,  Prasanna Muralidharan ,  David W. Overaker ,  Ramesh Marrey ,  Robert Burgermeister

发明人： Ryan Donovan ,  John F. Shanley ,  Prasanna Muralidharan ,  David W. Overaker ,  Ramesh Marrey ,  Robert Burgermeister

IPC分类号： A61F2/82

CPC分类号： A61F2/915 ,  A61F2/844 ,  A61F2/88 ,  A61F2/91 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2230/0054 ,  A61F2230/0069 ,  A61F2250/0068

摘要： The present invention relates to tissue-supporting medical devices and drug delivery systems, and more particularly to tubular flexible stents that are implanted within a body lumen of a living animal or human to support the organ, maintain patency and/or deliver drugs or agents. The tubular flexible stent has a cylindrical shape defining a longitudinal axis and includes a helical section having of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band. The band is wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings. At least one connector member extends between longitudinally adjacent helical windings of the band.

摘要翻译： 本发明涉及组织支撑医疗装置和药物递送系统，更具体地涉及植入活的动物或人体的体腔中以支持器官，维持开放和/或递送药物或药剂的管状柔性支架。 管状柔性支架具有限定纵向轴线的圆柱形形状，并且包括具有多个纵向取向的支柱构件的螺旋部分和连接周向相邻的支柱构件以形成带的多个周向定向的铰链构件。 该带围绕纵向轴线以大致螺旋状的方式缠绕以形成多个螺旋绕组。 至少一个连接器构件在带的纵向相邻螺旋绕组之间延伸。

公开(公告)号：US20060009836A1

公开(公告)日：2006-01-12

申请号：US11172103

申请日：2005-06-30

申请人： Robert Burgermeister ,  Thomas Duerig ,  Randy Grishaber ,  Ramesh Marrey ,  Jin Park ,  Mathew Krever

发明人： Robert Burgermeister ,  Thomas Duerig ,  Randy Grishaber ,  Ramesh Marrey ,  Jin Park ,  Mathew Krever

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2230/0013 ,  A61F2250/0029 ,  A61F2250/0036

摘要： This invention relates generally to expandable intraluminal medical devices for use within a body passageway or duct, and more particularly to an optimized stent having asymmetrical strut and loop members. In one embodiment of the invention the stent includes one or more members each having at least one component. The component has non-uniform cross-sections to achieve near-uniform stress distribution along the component when the component undergoes deformation.

摘要翻译： 本发明一般涉及用于体内通道或管道内的可扩张的腔内医疗装置，更具体地涉及具有不对称支柱和环构件的优化的支架。 在本发明的一个实施例中，支架包括一个或多个各自具有至少一个部件的部件。 该部件具有不均匀的横截面，以在部件经历变形时沿着部件实现近均匀的应力分布。

公开(公告)号：US09168161B2

公开(公告)日：2015-10-27

申请号：US12698717

申请日：2010-02-02

申请人： Ryan Donovan ,  John F. Shanley ,  Prasanna Muralidharan ,  David W. Overaker ,  Ramesh Marrey ,  Robert Burgermeister

发明人： Ryan Donovan ,  John F. Shanley ,  Prasanna Muralidharan ,  David W. Overaker ,  Ramesh Marrey ,  Robert Burgermeister

IPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2/88

CPC分类号： A61F2/915 ,  A61F2/844 ,  A61F2/88 ,  A61F2/91 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2230/0054 ,  A61F2230/0069 ,  A61F2250/0068

摘要： The present invention relates to tissue-supporting medical devices and drug delivery systems, and more particularly to tubular flexible stents that are implanted within a body lumen of a living animal or human to support the organ, maintain patency and/or deliver drugs or agents. The tubular flexible stent has a cylindrical shape defining a longitudinal axis and includes a helical section having of a plurality of longitudinally oriented strut members and a plurality of circumferentially oriented hinge members connecting circumferentially adjacent strut members to form a band. The band is wrapped about the longitudinal axis in a substantially helical manner to form a plurality of helical windings. At least one connector member extends between longitudinally adjacent helical windings of the band.

摘要翻译： 本发明涉及组织支撑医疗装置和药物递送系统，更具体地涉及植入活的动物或人体的体腔中以支持器官，维持开放和/或递送药物或药剂的管状柔性支架。 管状柔性支架具有限定纵向轴线的圆柱形形状，并且包括具有多个纵向取向的支柱构件的螺旋部分和连接周向相邻的支柱构件以形成带的多个周向定向的铰链构件。 该带围绕纵向轴线以大致螺旋状的方式缠绕以形成多个螺旋绕组。 至少一个连接器构件在带的纵向相邻螺旋绕组之间延伸。

公开(公告)号：US20080132995A1

公开(公告)日：2008-06-05

申请号：US11747500

申请日：2007-05-11

申请人： Robert Burgermeister ,  Ramesh Marrey ,  Vipul Bhupendra Dave ,  David Overaker

发明人： Robert Burgermeister ,  Ramesh Marrey ,  Vipul Bhupendra Dave ,  David Overaker

IPC分类号： A61F2/82

CPC分类号： A61F2/915 ,  A61F2/82 ,  A61F2002/825 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2250/0018 ,  A61F2250/0028 ,  A61F2250/0029 ,  A61F2250/0036 ,  A61F2250/0062 ,  A61F2250/0067 ,  A61F2250/0098 ,  A61L31/04 ,  A61L31/16 ,  A61L31/18 ,  A61L2300/416

摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics. The stent has a plurality of hoop components interconnected by a plurality of flexible connectors. The hoop components are formed as a continuous series of substantially longitudinally or axially oriented radial strut members and alternating substantially circumferentially oriented radial arc members. The geometry of the struts and arcs is such that when the stent is expanded, it has very high strains within a relatively small region. This strain localization results in what is often referred to as “hinging”, where the hinge is the small region within which the strains are very high.

摘要翻译： 生物相容性材料可以配置成任何数量的可植入医疗装置，包括腔内支架。 可以使用聚合材料来制造包括支架在内的任何这些装置。 支架可以是球囊扩张或自扩张。 聚合物材料可以包括添加剂如药物或其他生物活性剂以及不透射线剂。 通过聚合物的优先机械变形，聚合物链可以被取向以获得某些所需的性能特征。 支架具有通过多个柔性连接器互连的多个环部件。 环形部件形成为基本纵向或轴向定向的径向支柱构件和交替的基本上周向定向的径向弧形构件的连续系列。 支柱和弧的几何形状使得当支架膨胀时，其在相对小的区域内具有非常高的应变。 这种应变定位导致通常被称为“铰接”，其中铰链是应变非常高的小区域。