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1.发明申请XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权XYLANASES，核酸编码它们及其制备和使用方法公开(公告)号：US20080248160A1
公开(公告)日：2008-10-09
申请号：US10463720
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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2.发明授权Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US07504120B2
公开(公告)日：2009-03-17
申请号：US10463720
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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3.发明授权Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US08728769B2
公开(公告)日：2014-05-20
申请号：US12402421
申请日：2009-03-11
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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4.发明申请Xylanases, Nucleic Acids Encoding Them and Methods for Making and Using Them 有权木聚糖酶，编码它们的核酸及其制备和使用方法公开(公告)号：US20130337507A1
公开(公告)日：2013-12-19
申请号：US13835743
申请日：2013-03-15
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
IPC分类号： C12N9/24
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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5.发明申请XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权XYLANASES，核酸编码它们及其制备和使用方法公开(公告)号：US20090221051A1
公开(公告)日：2009-09-03
申请号：US12402421
申请日：2009-05-07
申请人： Brian STEER , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian STEER , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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公开(公告)号：US07547534B2
公开(公告)日：2009-06-16
申请号：US10517939
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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公开(公告)号：US20060003433A1
公开(公告)日：2006-01-05
申请号：US10517939
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
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8.发明授权Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US08043839B2
公开(公告)日：2011-10-25
申请号：US12279326
申请日：2007-02-14
申请人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： C12N9/24 , C12N1/20 , C12N1/15 , C12N1/16 , C12N1/19 , C12N15/70 , C12P21/06 , C07H21/04 , A01H5/00
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部-1,4-木糖苷键或内切-1,4-羟基化酶键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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9.发明申请XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权XYLANASES，核酸编码它们及其制备和使用方法公开(公告)号：US20090155238A1
公开(公告)日：2009-06-18
申请号：US12279326
申请日：2007-02-14
申请人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： A61K38/47 , C12N15/11 , C07H21/04 , C12N15/00 , C12N5/06 , C12N1/21 , C12N1/19 , C12P7/02 , A23K1/165 , D06L3/11 , C12P7/10 , D21C3/00 , C12N5/04 , A01K67/027 , A01H5/00 , C12N9/24 , C12P21/04
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部β-1,4-木糖苷键或内-A-1,4-ghicanase键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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公开(公告)号：US20080234480A1
公开(公告)日：2008-09-25
申请号：US10586093
申请日：2005-01-12
申请人： David Blum , Carsten Plueg , Tanja Reipen
发明人： David Blum , Carsten Plueg , Tanja Reipen
IPC分类号： C07D498/02
CPC分类号： C09B19/02
摘要： The invention relates to novel triphendioxazine pigments of formula (I) wherein X represents hydrogen or chlorine, while R1 represents phenyl substituted by one to five radicals from the group comprising C1-C4-alkyl, halogen, C1-C4-alkoxy, acetylamino, aminocarbonyl, methylaminocarbonyl and C1-C4-alkoxycarbonyl, or phenyl annelated in the 2,3- or 3,4- with a divalent radical of the formula —NH—(CO)m—NR2—, —CR2═CH—CO—NH—, —CR2═N—CO—NH—, —CO—NH—CO—NR2—, —CO—(NH)m—CO— or —O—(CO)m—NH— so as to form a five- or six-membered ring, R2 representing hydrogen, methyl, ethyl or phenyl and m representing 1 or 2.
摘要翻译： 本发明涉及式（I）的新型三苯并二恶嗪颜料，其中X表示氢或氯，而R 1表示被1至5个基团取代的苯基，所述基团包括C 1〜 -C 4 - 亚烷基，卤素，C 1 -C 4 - 烷氧基，乙酰氨基，氨基羰基，甲基氨基羰基和C 1 -C 4 - 或者在2,3-或3,4-中与式-NH-（CO）m的二价基团取代的苯基， -NR 2 - ， - CR 2 -CH-CO-NH-，-CR 2-N-CO-NH - ， - CO -NH-CO-NR 2 - ， - CO - （NH）m -CO-或-O-（CO）m -NH 以形成代表氢，甲基，乙基或苯基的5或6元环，m代表1或2。
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