公开(公告)号：US08679540B2

公开(公告)日：2014-03-25

申请号：US11808456

申请日：2007-06-11

申请人： Cécile Bonnet-Gonnet ,  David Chognot ,  Olivier Soula ,  Alain Constancis

发明人： Cécile Bonnet-Gonnet ,  David Chognot ,  Olivier Soula ,  Alain Constancis

IPC分类号： A61K9/14 ,  A61K9/50 ,  A61K39/395 ,  A61K39/00 ,  A61K31/00 ,  A61K38/00

CPC分类号： A61K9/10 ,  A61K9/1635 ,  A61K31/70 ,  A61K31/715 ,  A61K38/212 ,  A61K38/27 ,  A61K38/28 ,  A61K47/34

摘要： The present invention relates to novel pharmaceutical formulations based on aqueous colloidal suspensions for the prolonged release of one or more active principles, and to the applications, especially therapeutic applications, of these formulations. Formulations may include an aqueous colloidal suspension of low viscosity based on micrometric particles of a water-soluble, biodegradable, amphiphilic polymer carrying hydrophobic groups and ionizable hydrophilic groups that are at least partially ionized, said particles being capable of associating spontaneously and non-covalently with an active principle, at pH=7.0, under isotonic conditions. This suspension contains multivalent ions of opposite polarity to that of the hydrophilic groups, the ratio r, defined by the formula r=n×([IM]/[GI]), where n is the valency of said multivalent ions, [IM] is the molar concentration of multivalent ions, [GI] is the molar concentration of ionizable groups GI, being between 0.3 and 10.

摘要翻译： 本发明涉及基于用于延长释放一种或多种活性成分的水性胶体悬浮液以及这些制剂的应用，特别是治疗应用的新型药物制剂。 制剂可以包括基于水溶性，可生物降解的两亲性聚合物的微米颗粒的低粘度的水性胶体悬浮液，其携带至少部分电离的疏水基团和可离子化的亲水基团，所述颗粒能够自发地和非共价地缔合， 在pH = 7.0时，在等渗条件下的活性成分。 该悬浮液含有与亲水基团相反极性的多价离子，由式r = n×（[IM] / [GI]）定义的比率r，其中n是所述多价离子的价态，[IM] 是多价离子的摩尔浓度，[GI]是可离子化基团GI的摩尔浓度，介于0.3和10之间。

公开(公告)号：US06437040B1

公开(公告)日：2002-08-20

申请号：US09793169

申请日：2001-02-26

申请人： Olivier Anthony ,  Cécile Bonnet-Gonnet ,  Mathias Destarac ,  Roya Farhoosh ,  Mathieu Joanicot ,  Gilda Lizarraga ,  Roland Reeb ,  Jean-Marie Schwob

发明人： Olivier Anthony ,  Cécile Bonnet-Gonnet ,  Mathias Destarac ,  Roya Farhoosh ,  Mathieu Joanicot ,  Gilda Lizarraga ,  Roland Reeb ,  Jean-Marie Schwob

IPC分类号： C08L5300

摘要： The invention relates to water-soluble block copolymers comprising at least one block of hydrophobic nature and at least one block of hydrophilic nature, the block of hydrophobic nature exhibiting hydrophilic units in an amount of between 33% and 99% by weight with respect to the total weight of the units of the hydrophobic block. These copolymers are preferably diblocks or triblocks and are prepared by a polymerization process referred to as a living or controlled. Control of their hydrophilic-lipophilic balance makes it possible to adjust their solubility in water and their self-association properties. These copolymers can be used in particular as adhesion agents or wetting agents.

公开(公告)号：US06727204B1

公开(公告)日：2004-04-27

申请号：US09936860

申请日：2002-01-07

申请人： Vance Bergeron ,  Cécile Bonnet-Gonnet ,  Jean-Christophe Castaing ,  Giles Guerin

发明人： Vance Bergeron ,  Cécile Bonnet-Gonnet ,  Jean-Christophe Castaing ,  Giles Guerin

IPC分类号： A01N2524

CPC分类号： A01N25/24

摘要： The invention concerns the use, in an aqueous spray mixture comprising a phytosanitary formulation, of an anti-leaching agent comprising: at least a polyhydroxyl and/or polycarboxyl polymer or copolymer; at least a crosslinking agent comprising a metal selected among columns IVA, IB and IIIB of the periodic table; said anti-leaching agent being, in the aqueous spray mixture, in the form of an aqueous solution or dispersion having a polymer or copolymer concentration such that the viscosity of the anti-leaching agent is not more than 10 times the viscosity of the aqueous solution in polymer or copolymer without crosslinking agent, having the same concentration.

摘要翻译： 本发明涉及在包含植物检疫制剂的水性喷雾混合物中使用抗浸剂，其包括：至少多羟基和/或多羧基聚合物或共聚物; 至少含有选自周期表的IVA，IB和IIIB族的金属的交联剂; 所述防浸剂在水性喷雾混合物中为具有聚合物或共聚物浓度的水溶液或分散体的形式，使得防浸剂的粘度不超过水溶液粘度的10倍 在没有交联剂的聚合物或共聚物中，具有相同的浓度。

公开(公告)号：US07439292B2

公开(公告)日：2008-10-21

申请号：US10507329

申请日：2003-03-13

申请人： Mathias Destarac ,  Cécile Bonnet-Gonnet ,  Arnaud Cadix

发明人： Mathias Destarac ,  Cécile Bonnet-Gonnet ,  Arnaud Cadix

IPC分类号： C08L1/00

CPC分类号： C09D153/00 ,  C08F293/005 ,  C08L53/00 ,  C09D5/086 ,  C09D5/34 ,  C09D7/65

摘要： The invention relates to the use of a block copolymer having at least one block that comprises phosphate and/or phosphonate functions, as an additive for film-forming compositions, such as paint, latex or mastic which is optionally siliconised in order to ensure or promote the adhesion of the aforementioned compositions on a metallic surface or to protect said metallic surface against corrosion. The invention also relates to film-forming compositions comprising the abovementioned block copolymers.

摘要翻译： 本发明涉及使用具有至少一个包含磷酸酯和/或膦酸酯官能团的嵌段的嵌段共聚物作为成膜组合物的添加剂，例如涂料，胶乳或乳香，其任选地被硅化以确保或促进 上述组合物在金属表面上的粘附或保护所述金属表面免受腐蚀。 本发明还涉及包含上述嵌段共聚物的成膜组合物。

公开(公告)号：US07169309B2

公开(公告)日：2007-01-30

申请号：US10481658

申请日：2002-06-27

申请人： Etienne Fleury ,  Cécile Bonnet-Gonnet ,  Yvette Pescher

发明人： Etienne Fleury ,  Cécile Bonnet-Gonnet ,  Yvette Pescher

IPC分类号： C02F1/62

CPC分类号： C02F1/56 ,  C02F11/14 ,  C02F2101/20 ,  Y10S210/912 ,  Y10S210/913 ,  Y10S210/914

摘要： The invention relates to a particular polymer which is derived from a copolymer polysaccharide formed by a main chain comprising similar or different anhydrohexose units and branches including at least one neutral or anionic anhydropentose and/or anhydrohexose unit. Moreover, the invention relates to the use of said polymer in the treatment of aqueous media, in particular the treatment of aqueous effluents containing heavy metals, the treatment of waste water, drinking water and for sludge conditioning. Said derivative polymer comprises one or more units bearing an oxime function at least at position C2.

摘要翻译： 本发明涉及一种特定的聚合物，其衍生自由包含相似或不同的脱氢己糖单元的主链和包含至少一个中性或阴离子脱水西糖和/或脱水己糖单元的分支形成的共聚物多糖。 此外，本发明涉及所述聚合物在水性介质的处理中的用途，特别是处理含有重金属的含水废水，处理废水，饮用水和污泥调理。 所述衍生聚合物包含至少在C2位置具有肟功能的一个或多个单元。