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    SERRATION BALLOON
    2.
    发明公开
    SERRATION BALLOON 审中-公开

    公开(公告)号：US20230364394A1

    公开(公告)日：2023-11-16

    申请号：US18327626

    申请日：2023-06-01

    申请人： CAGENT VASCULAR, INC.

    发明人： Peter Schneider ,  Robert M. Giasolli

    IPC分类号： A61M25/10 ,  B29C70/72

    CPC分类号： A61M25/1029 ,  A61M25/104 ,  B29C70/72 ,  A61M2025/1031 ,  A61M2025/1086 ,  A61M2025/109 ,  B29L2031/7543

    摘要： A serration balloon can have a number of different components and can be made in a number of different manners. One or more longitudinally extending members with periodic raised wedges can be attached to a medical balloon. They can be attached with a fiber coating, a polymer coating, or other methods. A polymer matrix can be used to bond the longitudinally extending member to the surface of the balloon. The fiber coating can be, for example, a thread or mesh that secures the longitudinally extending member to the balloon. The medical balloon can be an angioplasty balloon, such as an off-the-shelf angioplasty balloon.

    System and method for plaque serration
    4.
    发明授权
    System and method for plaque serration 有权

    公开(公告)号：US11529501B2

    公开(公告)日：2022-12-20

    申请号：US17549672

    申请日：2021-12-13

    申请人： Cagent Vascular, Inc.

    发明人： Peter Schneider ,  Robert Giasolli

    IPC分类号： A61M25/10 ,  A61M25/00 ,  A61M37/00 ,  A61B17/20 ,  A61B17/3207 ,  A61B17/00 ,  A61B17/22

    摘要： A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty which microperforates the plaque with small sharp spikes acting as serrations for forming cleavage lines or planes in the plaque. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment enables subsequent angioplasty to be performed at low balloon pressures of about 4 atmospheres or less, reduces dissections, and avoids injury to the arterial wall. The subsequent angioplasty may be performed with a drug-eluting balloon (DEB) or drug-coated balloon (DCB). The pre-angioplasty perforation procedure enables more drug to be absorbed during DEB or DCB angioplasty, and makes the need for a stent less likely. Alternatively, any local incidence of plaque dissection after balloon angioplasty may be treated by applying a thin, ring-shaped tack at the dissection site only, rather than applying a stent over the overall plaque site.

    Method of enhancing drug uptake from a drug-eluting balloon
    6.
    发明授权
    Method of enhancing drug uptake from a drug-eluting balloon 有权

    公开(公告)号：US11166742B2

    公开(公告)日：2021-11-09

    申请号：US15212028

    申请日：2016-07-15

    申请人： CAGENT VASCULAR, INC.

    发明人： Peter Schneider ,  Robert M. Giasolli

    IPC分类号： A61B17/3207 ,  A61B17/22 ,  A61B17/20 ,  A61M25/10 ,  A61M25/00

    摘要： An intravascular device can comprise a carrier and an expansion apparatus. The device can be used for intravascular treatment of atherosclerotic plaque. The carrier can be reversibly expandable and collapsible within a vessel and can have ribbon strips extending between opposite ends in a longitudinal direction of the carrier. The ribbon strips can each be formed with a plurality of elongated protrusions thereon. The expansion apparatus can be used to actuate the ribbon strips each with the plurality elongated protrusions to pierce a luminal surface of the plaque with lines or patterns of microperforations which act as serrations for forming cleavage lines or planes in the plaque.

    INTRAVASCULAR DEVICE
    8.
    发明申请
    INTRAVASCULAR DEVICE 有权

    公开(公告)号：US20220087709A1

    公开(公告)日：2022-03-24

    申请号：US17494640

    申请日：2021-10-05

    申请人： CAGENT VASCULAR, INC.

    发明人： Peter Schneider ,  Robert M. Giasolli

    IPC分类号： A61B17/3207 ,  A61M25/00 ,  A61M25/10 ,  A61B17/22

    摘要： An intravascular device can comprise a carrier and an expansion apparatus. The device can be used for intravascular treatment of atherosclerotic plaque. The carrier can be reversibly expandable and collapsible within a vessel and can have ribbon strips extending between opposite ends in a longitudinal direction of the carrier. The ribbon strips can each be formed with a plurality of elongated protrusions thereon. The expansion apparatus can be used to actuate the ribbon strips each with the plurality elongated protrusions to pierce a luminal surface of the plaque with lines or patterns of microperforations which act as serrations for forming cleavage lines or planes in the plaque.

    PRE-ANGIOPLASTY SERRATION OF ATHEROSCLEROTIC PLAQUE ENABLING LOW PRESSURE BALLOON ANGIOPLASTY & AVOIDANCE OF STENTING
    9.
    发明申请
    PRE-ANGIOPLASTY SERRATION OF ATHEROSCLEROTIC PLAQUE ENABLING LOW PRESSURE BALLOON ANGIOPLASTY & AVOIDANCE OF STENTING 有权

    公开(公告)号：US20210353915A1

    公开(公告)日：2021-11-18

    申请号：US17389894

    申请日：2021-07-30

    申请人： Cagent Vascular, Inc.

    发明人： Peter Schneider ,  Robert Giasolli

    IPC分类号： A61M25/10 ,  A61B17/20 ,  A61B17/3207

    摘要： A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty which microperforates the plaque with small sharp spikes acting as serrations for forming cleavage lines or planes in the plaque. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment enables subsequent angioplasty to be performed at low balloon pressures of about 4 atmospheres or less, reduces dissections, and avoids injury to the arterial wall. The subsequent angioplasty may be performed with a drug-eluting balloon (DEB) or drug-coated balloon (DCB). The pre-angioplasty perforation procedure enables more drug to be absorbed during DEB or DCB angioplasty, and makes the need for a stent less likely. Alternatively, any local incidence of plaque dissection after balloon angioplasty may be treated by applying a thin, ring-shaped tack at the dissection site only, rather than applying a stent over the overall plaque site.

    SYSTEM AND METHOD FOR PLAQUE SERRATION
    10.
    发明申请
    SYSTEM AND METHOD FOR PLAQUE SERRATION 有权

    公开(公告)号：US20230091201A1

    公开(公告)日：2023-03-23

    申请号：US17983223

    申请日：2022-11-08

    申请人： Cagent Vascular, Inc.

    发明人： Peter Schneider ,  Robert Giasolli

    IPC分类号： A61M25/10 ,  A61B17/20 ,  A61B17/3207

    摘要： A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty which microperforates the plaque with small sharp spikes acting as serrations for forming cleavage lines or planes in the plaque. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment enables subsequent angioplasty to be performed at low balloon pressures of about 4 atmospheres or less, reduces dissections, and avoids injury to the arterial wall. The subsequent angioplasty may be performed with a drug-eluting balloon (DEB) or drug-coated balloon (DCB). The pre-angioplasty perforation procedure enables more drug to be absorbed during DEB or DCB angioplasty, and makes the need for a stent less likely. Alternatively, any local incidence of plaque dissection after balloon angioplasty may be treated by applying a thin, ring-shaped tack at the dissection site only, rather than applying a stent over the overall plaque site.