公开(公告)号：US11624062B2

公开(公告)日：2023-04-11

申请号：US16141901

申请日：2018-09-25

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Rustem F. Ismagilov ,  Matthew S. Curtis ,  Mary Arrastia ,  David A. Selck ,  Mitchell Guttman

IPC: C12N15/10 ,  B01L3/00 ,  C12Q1/6855 ,  G01N33/58 ,  G01N33/68 ,  C12Q1/6806 ,  C40B30/04 ,  C40B40/08 ,  C40B70/00

Abstract: Methods, systems and related compositions are provided to perform single-cell marking of a nucleic acid and/or protein in a sample based on in-cell or in-organelle barcoding of nucleic acid and/or protein complexes of the cell or organelle; the methods and systems herein described are configured to provide in-cell or in-organelle single-cell marked nucleic acid and/or protein complexes comprising a single-cell, cell-specific, or a single-cell organelle-specific marker.

公开(公告)号：US20150247190A1

公开(公告)日：2015-09-03

申请号：US14433602

申请日：2013-10-04

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Rustem F. Ismagilov ,  David A. Selck ,  Mikhail Karymov ,  Bing Sun

IPC: C12Q1/68 ,  G01N21/64 ,  C12Q1/70

CPC classification number: C12Q1/6851 ,  C12Q1/703 ,  C12Q2600/16 ,  G01N21/6428 ,  G01N21/6456 ,  G01N2021/6439 ,  G01N2021/6471 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/12 ,  G16B15/00 ,  C12Q2527/101 ,  C12Q2565/619 ,  C12Q2565/628

Abstract: Disclosed herein are methods and devices for assessing sample for the presence of a disease or organism using images from devices such as a consumer cell phones.

Abstract translation: 本文公开了使用来自诸如消费者手机的装置的图像评估疾病或生物体存在的样品的方法和装置。