公开(公告)号：US09895467B2

公开(公告)日：2018-02-20

申请号：US15154039

申请日：2016-05-13

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Robert H. Grubbs ,  Shane L. Mangold

IPC: C08F2/46 ,  C08F2/50 ,  C08G61/04 ,  A61L27/50 ,  C08F222/38 ,  A61L27/04 ,  A61L27/14 ,  A61F2/16 ,  A61F9/00

CPC classification number: A61L27/50 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2/1659 ,  A61F9/00 ,  A61L27/047 ,  A61L27/14 ,  A61L2400/06 ,  A61L2400/12 ,  A61L2430/16 ,  C08F2/48 ,  C08F222/385 ,  C08F220/20

Abstract: This disclosure relates compositions comprising upconverting nanocrystals and photoactive compositions and methods using these compositions to modify treat myopia and other ocular conditions. In some cases, the methods use near infrared irradiation to adjust the refractive power of light adjustable ocular lenses. Other methods improve the mechanical strength of the sclera directly.

公开(公告)号：US10398805B2

公开(公告)日：2019-09-03

申请号：US15893798

申请日：2018-02-12

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Robert H. Grubbs ,  Shane L. Mangold

IPC: C08F2/46 ,  C08F2/50 ,  C08G61/04 ,  A61L27/50 ,  C08F222/38 ,  A61L27/04 ,  A61L27/14 ,  A61F2/16 ,  A61F9/00 ,  C08F2/48

Abstract: This disclosure relates compositions comprising upconverting nanocrystals and photoactive compositions and methods using these compositions to modify treat myopia and other ocular conditions. In some cases, the methods use near infrared irradiation to adjust the refractive power of light adjustable ocular lenses. Other methods improve the mechanical strength of the sclera directly.