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公开(公告)号：US20170183344A1
公开(公告)日：2017-06-29
申请号：US15388178
申请日：2016-12-22
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Carmelida CAPALDI , Elisabetta ARMANI , Andrew Steven Robert JENNINGS , Christopher HURLEY
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: Compounds of formulae (I), (II), and (III), defined herein, are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
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公开(公告)号：US20150353561A1
公开(公告)日：2015-12-10
申请号：US14731786
申请日：2015-06-05
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Elisabetta ARMANI , Carmelida CAPALDI , Jonathan Mark SUTTON , Robert Andrew HEALD
IPC: C07D487/04
CPC classification number: C07D487/04 , A61K9/0075 , A61K9/008 , A61K31/519
Abstract: Compounds of formula (I), described herein, exhibit human neutrophil elastase inhibitory properties, and are useful for the treatment of diseases and conditions in which HNE is implicated.
Abstract translation: 本文所述的式（I）化合物显示人嗜中性粒细胞弹性蛋白酶抑制性质，并且可用于治疗涉及HNE的疾病和病症。
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公开(公告)号：US20170342056A1
公开(公告)日：2017-11-30
申请号：US15606064
申请日：2017-05-26
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Carmelida CAPALDI , Elisabetta ARMANI , Andrew Stephen Robert JENNINGS
IPC: C07D403/04 , C07C309/29 , C07D231/22 , C07D233/86
CPC classification number: C07D403/04 , C07C309/29 , C07D231/22 , C07D233/86 , C07D401/14
Abstract: Imidazolone and pyrazolone derivatives of formula (I) described herein exhibit human neutrophil elastase inhibitory properties and are useful for the therapy of diseases and conditions in which HNE is implicated.
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公开(公告)号：US20170183343A1
公开(公告)日：2017-06-29
申请号：US15388050
申请日：2016-12-22
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Carmelida CAPALDI , Elisabetta ARMANI , Andrew Steven Robert JENNINGS , Christopher HURLEY
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: Compounds of formula (I) defined herein are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
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公开(公告)号：US20140364411A1
公开(公告)日：2014-12-11
申请号：US14296730
申请日：2014-06-05
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Chi-Kit WOO , Lilian ALCARAZ , Carmelida CAPALDI
IPC: C07D471/10 , C07D471/04
CPC classification number: C07D471/10 , C07D471/04
Abstract: Compounds of formula (I) described herein are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
Abstract translation: 本文所述的式（I）化合物是p38 MAPK抑制剂，并且可用作治疗特别是呼吸道疾病的抗炎剂。
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Patent Agency Ranking
公开(公告)号：US20180354945A1
公开(公告)日：2018-12-13
申请号：US15987277
申请日：2018-05-23
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Carmelida CAPALDI , Elisabetta ARMANI , Christopher HURLEY , Barbara Giuseppina AVITABILE-WOO , Roberta LANARO , Neil Stuart JENNINGS
IPC: C07D471/04
CPC classification number: C07D471/04 , A61P11/00
Abstract: Compounds of formula (I) defined herein are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
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公开(公告)号：US20170183345A1
公开(公告)日：2017-06-29
申请号：US15388350
申请日：2016-12-22
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Carmelida CAPALDI , Elisabetta ARMANI , Andrew Steven Robert JENNINGS , Christopher HURLEY
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: Compounds of formula (I) defined herein are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
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公开(公告)号：US20180127410A9
公开(公告)日：2018-05-10
申请号：US15388050
申请日：2016-12-22
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Carmelida CAPALDI , Elisabetta ARMANI , Andrew Steven Robert JENNINGS , Christopher HURLEY
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: Compounds of formula (I) defined herein are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
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公开(公告)号：US20170340611A1
公开(公告)日：2017-11-30
申请号：US15606154
申请日：2017-05-26
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Jonathan Mark SUTTON , Robert Andrew HEALD , Andrew Stephen Robert JENNINGS , Carmelida CAPALDI , Elisabetta ARMANI
IPC: A61K31/4152 , C07D249/08 , C07D231/44 , C07D401/04 , A61K31/277
CPC classification number: A61K31/4152 , A61K31/277 , C07D231/44 , C07D249/08 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/14
Abstract: Pyrazolone derivatives of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for the treatment of diseases or conditions in which HNE is implicated.
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公开(公告)号：US20170166574A1
公开(公告)日：2017-06-15
申请号：US15375281
申请日：2016-12-12
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Elisabetta ARMANI , Carmelida CAPALDI
IPC: C07D487/04
CPC classification number: C07D487/04
Abstract: Triazolinone compounds of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for the therapy of diseases and conditions in which HNE is implicated.
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