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    IMPEDANCE REFLECTOR DETECTION SYSTEMS AND METHODS FOR USING THEM
    2.
    发明申请
    IMPEDANCE REFLECTOR DETECTION SYSTEMS AND METHODS FOR USING THEM 审中-公开

    公开(公告)号：US20190117112A1

    公开(公告)日：2019-04-25

    申请号：US16152289

    申请日：2018-10-04

    申请人： CIANNA MEDICAL, INC.

    发明人： Nikolai Rulkov ,  John E. Greene

    IPC分类号： A61B5/06 ,  A61B90/00 ,  A61B5/00

    摘要： An impedance reflector apparatus, systems, and methods are provided for detecting a marker implanted within tissue that includes a switch for changing a configuration of an antenna of the marker. The apparatus includes a set of transmit electrodes coupled to a signal generator for transmitting a drive current into tissue to generate an electromagnetic field around the marker, a set of receive electrodes configured to detect voltage signals within the tissue corresponding to the electromagnetic field, and a light source for delivering light pulses into the body to open and close the switch to change the configuration of the antenna of the marker. A processor coupled to the receive electrodes processes the detected voltage signals to identify changes in the electromagnetic field that are synchronized with the light pulses to determine whether the marker is operating properly.

    Passive tags, and systems and methods for using them
    3.
    发明授权
    Passive tags, and systems and methods for using them 有权

    公开(公告)号：US11351008B2

    公开(公告)日：2022-06-07

    申请号：US16841417

    申请日：2020-04-06

    申请人： Cianna Medical, Inc.

    发明人： Nikolai Rulkov ,  Michael John Lopez ,  John E. Greene

    IPC分类号： A61B5/06 ,  A61B90/00 ,  H01L23/60 ,  A61B90/98 ,  H01L25/16 ,  A61B34/20

    摘要： Markers, microwave probes, and related systems and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The marker includes an energy converter e.g., one or more photodiodes, for transforming energy pulses striking the marker into electrical energy, a switch, e.g., FET, coupled to the photodiodes such that light from a probe cause the switch to open and close. A pair of antenna wires are coupled to the switch to provide an antenna, the switch configured to open and close when light strikes the photodiodes to modulate signals from the probe reflected by the antenna back to the probe to identify the location of the marker. The marker also includes an electro static discharge (ESD) protection device coupled to the switch to provide protection against an electrostatic discharge event.

    IMPEDANCE REFLECTOR DETECTION SYSTEMS AND METHODS FOR USING THEM
    4.
    发明申请
    IMPEDANCE REFLECTOR DETECTION SYSTEMS AND METHODS FOR USING THEM 有权

    公开(公告)号：US20220386890A1

    公开(公告)日：2022-12-08

    申请号：US17805617

    申请日：2022-06-06

    申请人： Cianna Medical, Inc.

    发明人： Nikolai Rulkov ,  John E. Greene

    IPC分类号： A61B5/06 ,  A61B90/00 ,  A61B5/00

    摘要： An impedance reflector apparatus, systems, and methods are provided for detecting a marker implanted within tissue that includes a switch for changing a configuration of an antenna of the marker. The apparatus includes a set of transmit electrodes coupled to a signal generator for transmitting a drive current into tissue to generate an electromagnetic field around the marker, a set of receive electrodes configured to detect voltage signals within the tissue corresponding to the electromagnetic field, and a light source for delivering light pulses into the body to open and close the switch to change the configuration of the antenna of the marker. A processor coupled to the receive electrodes processes the detected voltage signals to identify changes in the electromagnetic field that are synchronized with the light pulses to determine whether the marker is operating properly.

    REFLECTOR MARKERS AND SYSTEMS AND METHODS FOR IDENTIFYING AND LOCATING THEM
    6.
    发明申请
    REFLECTOR MARKERS AND SYSTEMS AND METHODS FOR IDENTIFYING AND LOCATING THEM 审中-公开

    公开(公告)号：US20180279907A1

    公开(公告)日：2018-10-04

    申请号：US15928085

    申请日：2018-03-21

    申请人： CIANNA MEDICAL, INC.

    发明人： John E. Greene ,  Nikolai Rulkov ,  Jonathan White

    IPC分类号： A61B5/06 ,  A61B5/00 ,  A61B90/00 ,  H01Q1/27 ,  H01Q1/00 ,  A61B34/20 ,  G01S13/88 ,  G01S7/35 ,  G01S13/36

    摘要： Markers and related systems and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The marker includes one or more photosensitive diodes for transforming light pulses striking the marker into electrical energy, one or more antennas, and a switch coupled to the photodiodes and antennas such that the light pulses cause the switch to open and close and modulate radar signals reflected by the marker back to a source of the signals. The antenna(s) may include one or more wire elements extending from a housing, one or more antenna elements printed on a substrate, or one or more chip antennas. Optionally, the marker may include a processor coupled to the photodiodes for identifying signals in the light pulses or one or more coatings or filters to allow selective activation of the marker.

    PASSIVE TAGS, AND SYSTEMS AND METHODS FOR USING THEM
    7.
    发明申请
    PASSIVE TAGS, AND SYSTEMS AND METHODS FOR USING THEM 审中-公开
    被动标签，以及使用它们的系统和方法

    公开(公告)号：US20160354177A1

    公开(公告)日：2016-12-08

    申请号：US14934019

    申请日：2015-11-05

    申请人： CIANNA MEDICAL, INC.

    发明人： Nikolai Rulkov ,  Michael John Lopez ,  John E. Greene

    IPC分类号： A61B90/00

    CPC分类号： A61B90/39 ,  A61B5/062 ,  A61B5/064 ,  A61B90/04 ,  A61B90/37 ,  A61B90/98 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/3908 ,  A61B2090/3941 ,  A61B2090/3945 ,  A61B2090/397 ,  A61B2090/3975 ,  A61B2090/3979 ,  A61B2090/3987 ,  H01L23/60 ,  H01L2224/48091 ,  H01L2924/00014

    摘要： Markers, microwave probes, and related systems and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The marker includes an energy converter e.g., one or more photodiodes, for transforming energy pulses striking the marker into electrical energy, a switch, e.g., FET, coupled to the photodiodes such that light from a probe cause the switch to open and close. A pair of antenna wires are coupled to the switch to provide an antenna, the switch configured to open and close when light strikes the photodiodes to modulate signals from the probe reflected by the antenna back to the probe to identify the location of the marker. The marker also includes an electro static discharge (ESD) protection device coupled to the switch to provide protection against an electrostatic discharge event.

    摘要翻译： 提供标记物，微波探针以及相关的系统和方法用于定位患者体内的损伤，例如在乳房内。 标记包括能量转换器，例如用于将撞击标记的能量脉冲转换成电能的一个或多个光电二极管，耦合到光电二极管的开关，例如FET，使得来自探针的光使开关打开和关闭。 一对天线线耦合到开关以提供天线，该开关被配置为当光照射光电二极管时打开和闭合，以将来自由天线反射的探针的信号反馈回探头以识别标记的位置。 标记还包括耦合到开关的静电放电（ESD）保护装置，以提供防止静电放电事件的保护。

    NEEDLE LOCALIZATION REFLECTORS, SYSTEMS, AND METHODS
    9.
    发明申请
    NEEDLE LOCALIZATION REFLECTORS, SYSTEMS, AND METHODS 有权

    公开(公告)号：US20230028061A1

    公开(公告)日：2023-01-26

    申请号：US17811744

    申请日：2022-07-11

    申请人： Cianna Medical, Inc.

    发明人： Eduardo Chi Sing ,  John E. Greene ,  Nikolai Rulkov

    IPC分类号： A61B90/00 ,  A61B5/06

    摘要： Apparatus, systems, and methods are provided for localization of a needle within a patient's body using markers. In an exemplary embodiment, a probe includes a distal end for placement against a surface of the region and one or more antennas for transmitting electromagnetic signals into and receiving reflected signals from the region. A processor processes the modulated reflected signals at one or more of the surface locations to determine marker locations along the needle and generate a three-dimensional model of the body region and needle.

    Implantable markers, and systems and methods for using them
    10.
    发明授权
    Implantable markers, and systems and methods for using them 有权

    公开(公告)号：US11426256B2

    公开(公告)日：2022-08-30

    申请号：US15446944

    申请日：2017-03-01

    申请人： CIANNA MEDICAL, INC.

    发明人： John E. Greene ,  Nikolai Rulkov

    IPC分类号： A61B90/00 ,  A61B17/00 ,  A61B34/20 ,  A61B90/30

    摘要： Markers, probes, and related systems and methods are provided for localizing locations within a patient's body, e.g., a lesion within a breast. The marker includes an energy converter e.g., one or more photodiodes, for transforming light energy striking the marker into electrical energy, a storage device coupled to the energy converter for storing the electrical energy, a threshold element that closes a switch when the electrical energy reaches a predetermined threshold to discharge the electrical energy and cause the antenna to transmit a radio frequency (RF) signal. The system includes a probe that transmits light into the patient's body and a processor that correlate the frequency of the RF signals to a distance from the probe to the marker.