公开(公告)号：US20230088135A1

公开(公告)日：2023-03-23

申请号：US17760462

申请日：2021-05-13

Applicant: CJ CheilJedang Corporation

Inventor： Hayun LEE ,  Ju Eun KIM ,  Jihyun SHIM ,  Ji Hye LEE ,  Sung Gun LEE

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/77

Abstract: The present application relates to: a novel mutant polypeptide having isopropylmalate synthase activity; and a method for producing L-leucine by using same. L-leucine can be produced at high yield by using the mutant polypeptide according to an embodiment.

公开(公告)号：US20220411832A1

公开(公告)日：2022-12-29

申请号：US17756627

申请日：2020-11-24

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyun-jung BAE ,  Ju Eun KIM ,  Min Ji BAEK ,  Ji Hye LEE

IPC: C12P13/06 ,  C12N9/10 ,  C12N1/20 ,  C12N15/77

Abstract: A novel branched-chain amino acid aminotransferase variant and a method for producing leucine using the same.

公开(公告)号：US20220098569A1

公开(公告)日：2022-03-31

申请号：US17551890

申请日：2021-12-15

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Min Ji BAEK ,  Ji Hye LEE ,  So-jung PARK ,  Jee Yeon BAE

IPC: C12N9/00 ,  C12N15/52 ,  C12N15/77

Abstract: The present disclosure relates to an adenylosuccinate synthetase variant, a microorganism containing the same, and a method for preparing purine nucleotides using the microorganism.

公开(公告)号：US20210047665A1

公开(公告)日：2021-02-18

申请号：US16487721

申请日：2019-04-08

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Min Ji BAEK ,  Ji Hye LEE ,  So Jung PARK ,  Jee Yeon BAE

IPC: C12P19/32 ,  C12N15/77 ,  C12N9/00

Abstract: The present disclosure relates to a polynucleotide having a novel promoter activity, a composition for expressing a gene comprising the polynucleotide, a microorganism comprising the gene, and a method for preparing purine nucleotides using the microorganism.

公开(公告)号：US20200377558A1

公开(公告)日：2020-12-03

申请号：US16346725

申请日：2019-01-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jin Ah RHO ,  Byoung Hoon YOON ,  So-jung PARK ,  Min Ji BAEK ,  Ji Hye LEE

IPC: C07K14/34 ,  C12P19/32 ,  C12R1/15 ,  C12N1/20

Abstract: The present disclosure relates to a novel protein variant having an activity of exporting 5′-inosine monophosphate, a microorganism comprising the protein variant, and a method for preparing 5′-inosine monophosphate using the microorganism.

公开(公告)号：US20200347346A1

公开(公告)日：2020-11-05

申请号：US16960449

申请日：2019-01-25

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hee Ju KIM ,  Bo Ram LIM ,  Byoung Hoon YOON ,  Min Ji BAEK ,  Ji Hye LEE

IPC: C12N1/20 ,  C12P19/32

Abstract: The present disclosure relates to a microorganism of the genus Corynebacterium producing a purine nucleotide and a method for producing a purine nucleotide using the same.

公开(公告)号：US20200032305A1

公开(公告)日：2020-01-30

申请号：US16473941

申请日：2017-10-20

Applicant: CJ Cheiljedang Corporation

Inventor： Ji Hye LEE ,  Byeong Cheol SONG ,  Ae Ji JEON ,  Jong Hyun KIM ,  Hye Won KIM

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/52 ,  C12N15/77

Abstract: A novel modified polypeptide having an isopropylmalate synthase activity, a polynucleotide encoding the same, a microorganism comprising the polypeptide, and a method of producing L-leucine by culturing the microorganism.

公开(公告)号：US20240093252A1

公开(公告)日：2024-03-21

申请号：US18274912

申请日：2022-01-28

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hayun LEE ,  Ju Eun KIM ,  Ji Hye LEE

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/77

CPC classification number: C12P13/06 ,  C12N9/1025 ,  C12N15/77 ,  C12R2001/15 ,  C12Y203/03013

Abstract: The present disclosure relates to an isopropylmalate synthase variant and a method of producing L-leucine using the same.

公开(公告)号：US20240093163A1

公开(公告)日：2024-03-21

申请号：US18274196

申请日：2021-11-18

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hayun LEE ,  Ju Eun KIM ,  Ji Hye LEE ,  Heeseok LEE ,  Kyungrim KIM

IPC: C12N9/10 ,  C12P13/06 ,  C12P13/08

CPC classification number: C12N9/1085 ,  C12P13/06 ,  C12P13/08 ,  C12Y205/01054

Abstract: The present application relates to an aroG aldolase (phospho-2-dehydro-3-deoxyheptonate aldolase) variant, a microorganism comprising the same, and a method for producing amino acids using the same.

公开(公告)号：US20220380821A1

公开(公告)日：2022-12-01

申请号：US17296375

申请日：2021-02-19

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ji Hyun LEE ,  Sojung PARK ,  Hee Su KWON ,  Dae Young KIM ,  Ji Hye LEE

IPC: C12P19/32 ,  C12N15/77 ,  C07K14/34

Abstract: Provided are a microorganism of the genus Corynebacterium which produces a purine nucleotide, and a method of producing a purine nucleotide using the microorganism.