公开(公告)号：US20210230572A1

公开(公告)日：2021-07-29

申请号：US17225756

申请日：2021-04-08

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji JEON ,  Byeong Cheol SONG ,  Ji Hye LEE ,  Jong Hyun KIM ,  Hye Won KIM

IPC: C12N9/88 ,  C12P13/06 ,  C12P13/08 ,  C12N15/77 ,  C12N9/10

Abstract: The present disclosure relates to a novel acetohydroxy acid synthase, a microorganism comprising the same, or a method for producing an L-branched-chain amino acid using the same.

公开(公告)号：US20190023749A1

公开(公告)日：2019-01-24

申请号：US16156778

申请日：2018-10-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Sol KIM ,  Hye Won KIM ,  Jin Sook CHANG ,  In Hwa YOO

IPC: C07K14/245 ,  C12P13/00 ,  C12P13/06 ,  C12N15/63 ,  C12P13/12 ,  C12N9/16 ,  C12N9/10 ,  C12N9/04 ,  C12N15/52

Abstract: The present invention relates to an RhtB (homoserine/homoserine lactone export transporter) protein variant having an enhanced ability to export O-phosphoserine (OPS) that is a precursor of L-cysteine, a polynucleotide encoding the protein, a vector comprising the polynucleotide, an OPS-producing microorganism comprising the protein variant, a method of producing O-phosphoserine using the microorganism, and a method for preparing cysteine or its derivatives, which comprises reacting O-phosphoserine, produced by the method above, with a sulfide in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism that expresses OPSS.

公开(公告)号：US20210324349A1

公开(公告)日：2021-10-21

申请号：US17357196

申请日：2021-06-24

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji JEON ,  Byeong Cheol SONG ,  Ji Hye LEE ,  Jong Hyun KIM ,  Hye Won KIM

IPC: C12N9/10 ,  C12P13/06 ,  C12P13/08

Abstract: The present disclosure relates to a novel acetohydroxy acid synthase, a microorganism comprising the same, or a method for producing an L-branched-chain amino acid using the same.

公开(公告)号：US20210040457A1

公开(公告)日：2021-02-11

申请号：US17076057

申请日：2020-10-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji JEON ,  Byeong Cheol SONG ,  Ji Hye LEE ,  Jong Hyun KIM ,  Hye Won KIM

IPC: C12N9/10 ,  C12P13/06 ,  C12P13/08

Abstract: The present disclosure relates to a novel acetohydroxy acid synthase, a microorganism comprising the same, or a method for producing an L-branched-chain amino acid using the same.

公开(公告)号：US20200080071A1

公开(公告)日：2020-03-12

申请号：US16692558

申请日：2019-11-22

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ae Ji JEON ,  Byeong Cheol SONG ,  Ji Hye LEE ,  Jong Hyun KIM ,  Hye Won KIM

IPC: C12N9/88 ,  C12N15/77 ,  C12P13/08 ,  C12P13/06

Abstract: The present disclosure relates to a novel acetohydroxy acid synthase, a microorganism comprising the same, or a method for producing an L-branched-chain amino acid using the same.

公开(公告)号：US20170342114A1

公开(公告)日：2017-11-30

申请号：US15679671

申请日：2017-08-17

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Sol KIM ,  Hye Won KIM ,  Jin Sook CHANG ,  In Hwa YOO

IPC: C07K14/245 ,  C12P13/06 ,  C12P13/00 ,  C12N15/63 ,  C12N15/52 ,  C12N9/16 ,  C12N9/10 ,  C12P13/12 ,  C12N9/04

CPC classification number: C07K14/245 ,  C12N9/0006 ,  C12N9/1096 ,  C12N9/16 ,  C12N15/52 ,  C12N15/63 ,  C12P13/005 ,  C12P13/06 ,  C12P13/12

Abstract: The present invention relates to an RhtB (homoserine/homoserine lactone export transporter) protein variant having an enhanced ability to export O-phosphoserine (OPS) that is a precursor of L-cysteine, a polynucleotide encoding the protein, a vector comprising the polynucleotide, an OPS-producing microorganism comprising the protein variant, a method of producing O-phosphoserine using the microorganism, and a method for preparing cysteine or its derivatives, which comprises reacting O-phosphoserine, produced by the method above, with a sulfide in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism that expresses OPSS.

公开(公告)号：US20200208182A1

公开(公告)日：2020-07-02

申请号：US16622490

申请日：2018-06-14

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Seon Hye KIM ,  Su Jin PARK ,  Kyoung Min LEE ,  Kyungsu NA ,  Hong Xian LI ,  Hyun-jung BAE ,  Jihyun SHIM ,  Young Lyeol YANG ,  Hye Won UM ,  Hyo Hyoung LEE ,  Min Gyeong KANG ,  Hye Won KIM ,  Byeong Cheol SONG ,  Haena OH ,  Han Hyoung LEE

IPC: C12P13/10 ,  C12P13/00

Abstract: The present disclosure relates to a novel polypeptide having an ability to export an ornithine-based product, and a method for producing an ornithine-based product using the same.

公开(公告)号：US20200032305A1

公开(公告)日：2020-01-30

申请号：US16473941

申请日：2017-10-20

Applicant: CJ Cheiljedang Corporation

Inventor： Ji Hye LEE ,  Byeong Cheol SONG ,  Ae Ji JEON ,  Jong Hyun KIM ,  Hye Won KIM

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/52 ,  C12N15/77

Abstract: A novel modified polypeptide having an isopropylmalate synthase activity, a polynucleotide encoding the same, a microorganism comprising the polypeptide, and a method of producing L-leucine by culturing the microorganism.

公开(公告)号：US20190338242A1

公开(公告)日：2019-11-07

申请号：US16474291

申请日：2017-12-28

Applicant: CJ Cheiljedang Corporation

Inventor： Se Hoon SIM ,  Seo-Yun KIM ,  Sol KIM ,  Hye Won KIM ,  Inhwa YOO

IPC: C12N1/20 ,  C12P13/06 ,  C12P13/12

Abstract: The present application relates to a microorganism producing O-phosphoserine and a method for producing O-phosphoserine, cysteine or a cysteine derivative using same.

公开(公告)号：US20170260556A1

公开(公告)日：2017-09-14

申请号：US15329921

申请日：2015-08-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Sol KIM ,  In Hwa YOO ,  Jin Sook CHANG ,  Hye Won KIM

IPC: C12P13/12 ,  C12P13/06 ,  C12N9/10 ,  C12N9/16 ,  C12N9/04

CPC classification number: C12P13/12 ,  C12N9/0006 ,  C12N9/1085 ,  C12N9/1096 ,  C12N9/16 ,  C12P13/06 ,  C12Y101/01095 ,  C12Y205/01065 ,  C12Y206/01052 ,  C12Y301/03003

Abstract: The present invention relates to a microorganism, wherein the activity of a polypeptide capable of exporting O-phosphoserine (OPS) is enhanced, and a method of producing O-phosphoserine, cysteine, or a cysteine derivative using the microorganism.