公开(公告)号：US20180318200A1

公开(公告)日：2018-11-08

申请号：US15771246

申请日：2016-10-25

Applicant: COLGATE-PALMOLIVE COMPANY ,  BASF SE

Inventor： LaTonya KILPATRICK-LIVERMAN ,  Jianhong QIU ,  Lynette ZAIDEL ,  Thomas SUBKOWSKI ,  Stefan JENEWEIN ,  Marvin KAROS ,  Claus BOLLSCHWEILER ,  Volker WENDEL ,  Nina SCHNEIDER ,  Ralph Peter SANTARPIA

IPC: A61K8/64 ,  A61K8/41 ,  A61K8/34 ,  A61K8/21 ,  A61Q11/00

CPC classification number: A61K8/645 ,  A61K8/21 ,  A61K8/345 ,  A61K8/416 ,  A61K38/011 ,  A61K2800/524 ,  A61Q11/00

Abstract: Provided herein is a mouthwash comprising partially hydrolyzed plant protein, which is useful, e.g., in methods of repairing or inhibiting dental erosion, promoting dental remineralization, and/or enhancing the anti-cavity effects of fluoride.

公开(公告)号：US20180353416A1

公开(公告)日：2018-12-13

申请号：US15771258

申请日：2016-10-25

Applicant: COLGATE-PALMOLIVE COMPANY ,  BASF SE

Inventor： LaTonya KILPATRICK-LIVERMAN ,  Jianhong QIU ,  Lynette ZAIDEL ,  Thomas SUBKOWSKI ,  Stefan JENEWEIN ,  Marvin KAROS ,  Claus BOLLSCHWEILER ,  Volker WENDEL ,  Nina SCHNEIDER ,  Ralph Peter SANTARPIA

IPC: A61K8/64 ,  A61Q11/00 ,  A61K8/21

CPC classification number: A61K8/645 ,  A61K8/21 ,  A61K8/345 ,  A61K8/416 ,  A61K38/011 ,  A61K2800/524 ,  A61Q11/00

Abstract: Provided herein are oral care compositions comprising partially hydrolyzed plant protein, which are useful in methods of repairing or inhibiting dental erosion, promoting dental remineralization, and/or enhancing the anti-cavity effects of fluoride.

公开(公告)号：US20170247741A1

公开(公告)日：2017-08-31

申请号：US15512125

申请日：2014-10-06

Applicant: Colgate-Palmolive Company

Inventor： Luciana Rinaudi Marron ,  Richard SULLIVAN ,  David SURIANO ,  Aarti REGE ,  Ralph Peter SANTARPIA

IPC: C12Q1/18 ,  G01N1/28 ,  C12N1/20

CPC classification number: C12Q1/18 ,  C12N1/20 ,  G01N1/2806

Abstract: The present disclosure provides an oral biofilm model including a substrate including a first surface, a second surface, and a plurality of specimens fixedly attached to the first surface, wherein an oral biofilm is capable of forming on the specimen. The surface roughness of at least one of the specimens of the plurality is less than or greater than a surface roughness of at least a second specimen of the plurality. The oral biofilm model also includes a body having sides and a bottom defining a vessel. The body is adapted to receive the substrate and the plurality of specimens and is further adapted to receive a fluid. Methods of forming oral biofilms and methods for identifying an agent for reducing or inhibiting biofilm formation are also provided.