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公开(公告)号：US20230001056A1
公开(公告)日：2023-01-05
申请号：US17781084
申请日：2020-11-27
申请人： CORTRONIK GMBH
发明人： Stefan Oschatz , Sabine Illner , Jonathan Ortelt , Daniela Arbeiter , Michael Teske , Heinz Mueller , Niels Grabow , Carsten Momma , Klaus-Peter Schmitz
摘要： A material includes nonwoven fibers and a surface modification that crosslinks the nonwoven fibers together. The surface modification can include chemical reactive groups. The reactive groups can be selected from diisocyanates, alcohols, epoxides, imides, amides, imines, amines, diacrylates, disiloxanes and disilazanes. A method of forming the material electrospins fiber material in the form of fibers into a nonwoven material. A surface modification is introduced to the fibers either by modifying the fiber material before the electrospinning or by modifying the fiber surface after the electrospinning. The fibers are crosslinked to form the crosslinked nonwoven material.
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公开(公告)号：US20230009211A1
公开(公告)日：2023-01-12
申请号：US17780144
申请日：2020-11-24
申请人： CORTRONIK GMBH
发明人： Stefanie Kohse , Kerstin Lebahn , Niels Grabow , Dalibor Bajer , Swen Grossmann , Klaus-Peter Schmitz , Heinz Mueller , Carsten Momma , Sabine Illner , Daniela Arbeiter , Thomas Eickner
摘要： An intraluminal endoprosthesis such as a stent has a metallic supporting structure and a sleeve surrounding the supporting structure. The sleeve can include fibres which are applied to an outer side of the supporting structure. The fibres each have a polymer core and a hydrogel casing connected thereto. The sleeve can also be formed from a fibre mixture of polymer and hydrogel fibres.
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公开(公告)号：US20230293773A1
公开(公告)日：2023-09-21
申请号：US17768321
申请日：2020-10-07
申请人： CORTRONIK GMBH
发明人： Nicolas Degen , Sebastian Kaule , Sabine Illner , Stefanie Kohse , Niels Grabow , Klaus-Peter Schmitz
CPC分类号： A61L27/40 , A61L27/52 , A61L2400/02
摘要： A sealing material suitable for a medical implant. The material includes a composite structure of a first component, a second component and a third component. The first component includes at least one biologically inert polymer. The second component includes a hydrogel, which swells up after contact with an aqueous solution by a first volume increase within a first time period. The third component includes a hygroscopic matrix, which swells up after contact with an aqueous solution by a second volume increase within a second time period. The second time period is shorter than the first time period.
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4.发明申请公开(公告)号：US20180042693A1
公开(公告)日：2018-02-15
申请号：US15665959
申请日：2017-08-01
申请人： CORTRONIK GmbH
发明人： Ullrich Bayer , Daniel Lootz , Niels Grabow , Sabine Illner , Thomas Eickner , Klaus-Peter Schmitz
CPC分类号： A61B90/39 , A61B2017/00898 , A61B2017/00929 , A61B2090/3966 , A61B2090/3991 , A61L31/022 , A61L31/10 , A61L31/145 , A61L31/148 , A61L31/18
摘要： A medical implant that includes a scaffold having at least one receptacle for an X-ray marker. The scaffold includes a first metal. At least one (preferably monolithic) X-ray marker is disposed in the receptacle. The X-ray marker includes a second metal. An electrically insulating coating is upon the X-ray marker to prevent corrosion-promoting contact between the X-ray marker and the scaffold.
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公开(公告)号：US20230372103A1
公开(公告)日：2023-11-23
申请号：US17918810
申请日：2021-04-09
申请人： CORTRONIK GmbH
发明人： Michael Stiehm , Wolfram Schmidt , Niels Grabow , Jonas Keiler , Maria Reumann , Andreas Wree , Andreas Hof , Heinz Mueller , Carsten Momma , Klaus-Peter Schmitz , Karsten Koop , Julia Schubert , Kerstin Lebahn , Sabine Illner , Sabine Kischkel , Jonathan Ortelt
IPC分类号： A61F2/24
CPC分类号： A61F2/2475 , A61F2230/0017
摘要： A venous valve prosthesis for transporting a flow of body fluid in a vessel in a predetermined direction includes
includes a hollow-cylindrical support structure. A skirt is connected to the support structure and forms a closed, circumferential jacket of the support structure. The prosthesis also includes a valve leaflet arrangement with a first valve leaflet and a second valve leaflet, each being connected to the skirt. A downstream edge of the first valve leaflet and a downstream edge of the second valve leaflet are opposite to each other and configured in such a manner that in a first state of the valve leaflet arrangement they form an opening for blood to flow through in the predetermined direction and in a second state of the valve leaflet arrangement the opening is closed and to prevent a backflow of blood in a direction opposite to the predetermined direction. A ratio of the inner diameter of the support structure to its length in the predetermined direction is at most 1.-
公开(公告)号：US20230024499A1
公开(公告)日：2023-01-26
申请号：US17779490
申请日：2020-11-18
申请人： CORTRONIK GMBH
发明人： Stefanie Kohse , Kerstin Lebahn , Niels Grabow , Dalibor Bajer , Swen Grossmann , Klaus-Peter Schmitz , Heinz Mueller , Carsten Momma , Sabine Illner , Daniela Arbeiter , Thomas Eickner
摘要： An intraluminal endoprosthesis has a biodegradable metallic supporting structure and a biodegradable sleeve surrounding the supporting structure. The sleeve includes fibres applied to the outer side of the supporting structure. The sleeve can be formed from fibres that each have a polymer core and a hydrogel casing. The sleeve can the sleeve be formed from a fibre mixture of polymer fibres and hydrogel fibres.
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公开(公告)号：US20220411966A1
公开(公告)日：2022-12-29
申请号：US17779535
申请日：2020-11-17
申请人： CORTRONIK GMBH
发明人： Stefanie Kohse , Kerstin Lebahn , Niels Grabow , Dalibor Bajer , Swen Grossmann , Klaus-Peter Schmitz , Heinz Mueller , Carsten Momma
摘要： A method for producing an intraluminal endoprosthesis. The method forms a sheath on a support structure of the endoprosthesis from polymer fibres. A polymer solution is dispensed from a nozzle by f electrospinning. The polymer solution includes at least one biodegradable polymer polymer and at least one additive. The additive is selected from the group consisting of: 1,3-dioxan-2-one, 1,4-dioxan-2-one, triethyl citrate, glycerol triacetate, n-butyryl tri-n-hexyl citrate, polyethylene glycol, L-α phosphatidylcholine.
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公开(公告)号：US10828126B2
公开(公告)日：2020-11-10
申请号：US15665959
申请日：2017-08-01
申请人： CORTRONIK GmbH
发明人： Ullrich Bayer , Daniel Lootz , Niels Grabow , Sabine Illner , Thomas Eickner , Klaus-Peter Schmitz
摘要： A medical implant that includes a scaffold having at least one receptacle for an X-ray marker. The scaffold includes a first metal. At least one (preferably monolithic) X-ray marker is disposed in the receptacle. The X-ray marker includes a second metal. An electrically insulating coating is upon the X-ray marker to prevent corrosion-promoting contact between the X-ray marker and the scaffold.
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