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公开(公告)号:US20170291896A1
公开(公告)日:2017-10-12
申请号:US15507956
申请日:2015-09-02
发明人: Ying SHI , Qingzhi GAO , Yi MI , Xuliang WANG
IPC分类号: C07D471/04
CPC分类号: C07D471/04 , A61K31/437 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/55
摘要: Disclosed are a compound of formula (I), a tautomer, an optical isomer or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the above-mentioned compounds. The above-mentioned compounds have the activity of inhibiting Xa factor positive effect, and can be used for the preparation of a medicament for preventing and/or treating diseases inhibiting Xa factor positive effect in case of low bleeding risk.
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公开(公告)号:US20180312462A1
公开(公告)日:2018-11-01
申请号:US15763807
申请日:2016-09-30
发明人: Ying SHI , Yi MI , Hanyu YANG , Xuliang WANG , Denghuang GONG , Min BAI , Xiaozhuo CHEN , Yujie CHEN , Xuejiao ZHANG , Yuxiu MA , Qingzhi GAO
IPC分类号: C07C235/84 , C07D237/24 , C07D401/06 , C07D213/82 , C07D213/81 , C07C231/12 , C07D211/16 , C07D211/46 , C07D295/192 , C07C237/38 , C07C237/42 , C07C275/38 , C07C273/18 , C07D277/82 , C07D333/38 , C07D409/06 , C07D403/12 , C07D401/12
CPC分类号: C07C235/84 , A61K31/44 , A61K31/50 , C07C231/12 , C07C237/38 , C07C237/42 , C07C273/1854 , C07C275/38 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07D211/16 , C07D211/46 , C07D213/81 , C07D213/82 , C07D237/24 , C07D277/82 , C07D295/192 , C07D333/38 , C07D401/06 , C07D401/12 , C07D403/12 , C07D409/06
摘要: The present invention relates to a benzamide derivative of general formula I, a drug composition containing same and a use thereof as a drug, wherein the definitions of R1, Z and Q are as described in the description.
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