METHOD FOR CALIBRATING AN APPARATUS FOR MEASURING THE ABSORBANCE OF LIGHT BY A SUBSTANCE

    公开(公告)号:US20230204495A1

    公开(公告)日:2023-06-29

    申请号:US17996581

    申请日:2021-04-27

    申请人: CYTIVA SWEDEN AB

    IPC分类号: G01N21/27 G01N21/31

    CPC分类号: G01N21/274 G01N21/31

    摘要: The present invention relates to computer implemented method performed by a computer (110) configured to calibrate an apparatus for measuring the absorbance of light of a substance (131) for a chromatography system (100), the apparatus (131) comprising a conduit (C) for enabling a fluid to be measured, a light emitter (LE) configured to emit light along an optical path (OP) to a light sensor (S) configured to measure the emitted light, the optical path intersecting the conduit (C), a rotating disc (D) having one or more optical filters, each of the one or more optical filters is arranged with its center passing through the optical path (OP) when rotating, an actuator configured to rotate the disc (D) dependent on a control signal, to the method comprising controlling rotation of (710) the disc (D) to a first position where a first filter, of the one or more optical filters, intersects the optical path (OP) at a first point (P1), measuring (720) a first light absorption value, controlling rotation of (730) the disc (D) to a second position, different to the first position, where the first filter still intersects the optical path (OP) at a second point (P2), measuring (740) a second light absorption value, generating (750) an aggregated light absorption value, calibrating (760) the apparatus (131) by comparing the aggregated light absorption value to a reference light absorption value.

    Pumps
    3.
    发明授权
    Pumps 有权

    公开(公告)号:US11815075B2

    公开(公告)日:2023-11-14

    申请号:US16645022

    申请日:2018-09-06

    申请人: Cytiva Sweden AB

    IPC分类号: F04B1/047 F04B43/02

    摘要: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).

    A Diaphragm Pump
    4.
    发明申请

    公开(公告)号:US20220275798A1

    公开(公告)日:2022-09-01

    申请号:US17634455

    申请日:2020-06-24

    申请人: Cytiva Sweden AB

    IPC分类号: F04B43/02 F04B53/10 F04B43/00

    摘要: A diapharagm pump for a bioprocess system comprises a pump head (1; 101; 201; 301) comprising: a common inlet (3); a common outlet (5); a plurality of pump cavities (7) each including at least one cooperating pair of one-way valves, the at least one pair of one-way valves including an inlet valve (9) and an outlet valve (11), wherein the respective inlet valves (9) are in fluid communication with the common inlet (3) and the respective outlet valves (11) are in fluid communication with the common outlet (5) and wherein a centre of the outlet valve (11) for each pump cavity is positionable above a centre of the inlet valve (9) for the same pump cavity when the diaphragm pump is oriented for use to inhibit trapped gas; and a plurality of moveable diaphragms (13) each respectively provided in a respective of said pump cavities (7) for varying a volume of the pump cavities. The system further comprises a pump drive (31) which is configured to transfer a motion to the diaphragms (13) of the pump head (1; 101; 201) for accomplishing a fluid displacement from the common inlet (3) to the common outlet (5) of the pump head (1; 101; 201; 301) as a result of said varying of the volume of the pump cavities (7).

    Improvements In and Relating to Pumps

    公开(公告)号:US20210222681A1

    公开(公告)日:2021-07-22

    申请号:US16645022

    申请日:2018-09-06

    申请人: Cytiva Sweden AB

    IPC分类号: F04B1/047 F04B43/02

    摘要: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).