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公开(公告)号:US20230204495A1
公开(公告)日:2023-06-29
申请号:US17996581
申请日:2021-04-27
申请人: CYTIVA SWEDEN AB
发明人: Hanno Ehring , David Gronowitz , Lars Rosengren
CPC分类号: G01N21/274 , G01N21/31
摘要: The present invention relates to computer implemented method performed by a computer (110) configured to calibrate an apparatus for measuring the absorbance of light of a substance (131) for a chromatography system (100), the apparatus (131) comprising a conduit (C) for enabling a fluid to be measured, a light emitter (LE) configured to emit light along an optical path (OP) to a light sensor (S) configured to measure the emitted light, the optical path intersecting the conduit (C), a rotating disc (D) having one or more optical filters, each of the one or more optical filters is arranged with its center passing through the optical path (OP) when rotating, an actuator configured to rotate the disc (D) dependent on a control signal, to the method comprising controlling rotation of (710) the disc (D) to a first position where a first filter, of the one or more optical filters, intersects the optical path (OP) at a first point (P1), measuring (720) a first light absorption value, controlling rotation of (730) the disc (D) to a second position, different to the first position, where the first filter still intersects the optical path (OP) at a second point (P2), measuring (740) a second light absorption value, generating (750) an aggregated light absorption value, calibrating (760) the apparatus (131) by comparing the aggregated light absorption value to a reference light absorption value.
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公开(公告)号:US20240018952A1
公开(公告)日:2024-01-18
申请号:US18465810
申请日:2023-09-12
申请人: Cytiva Sweden AB
发明人: Andreas Torbjorn Lundin , Klas Marteleur , Mats Lundkvist , Andreas Marcstrom , David Gronowitz
CPC分类号: F04B1/047 , F04B43/026 , F04B43/02
摘要: A multiple cavity reciprocating positive displacement pump comprising plural pump cavities each including at least one pair of one-way valves the at least one pair including an inlet valve and an outlet valve, the pump being characterised in that respective inlet valves are in fluid communication with a common inlet and respective outlet valves are in fluid communication with a common outlet. The multiple cavities may include diaphragm arranged in a radial configuration for more uniform pressure output.
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公开(公告)号:US11815075B2
公开(公告)日:2023-11-14
申请号:US16645022
申请日:2018-09-06
申请人: Cytiva Sweden AB
发明人: Andreas Torbjorn Lundin , Klas Marteleur , Mats Lundkvist , Andreas Marcstrom , David Gronowitz
CPC分类号: F04B1/047 , F04B43/02 , F04B43/026
摘要: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).
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公开(公告)号:US20220275798A1
公开(公告)日:2022-09-01
申请号:US17634455
申请日:2020-06-24
申请人: Cytiva Sweden AB
发明人: Klaus Gebauer , Andreas Lundin , Andreas Marcstrom , David Gronowitz , Bjorn Johansson , Mats Nilsson , Bjorn Olovsson
摘要: A diapharagm pump for a bioprocess system comprises a pump head (1; 101; 201; 301) comprising: a common inlet (3); a common outlet (5); a plurality of pump cavities (7) each including at least one cooperating pair of one-way valves, the at least one pair of one-way valves including an inlet valve (9) and an outlet valve (11), wherein the respective inlet valves (9) are in fluid communication with the common inlet (3) and the respective outlet valves (11) are in fluid communication with the common outlet (5) and wherein a centre of the outlet valve (11) for each pump cavity is positionable above a centre of the inlet valve (9) for the same pump cavity when the diaphragm pump is oriented for use to inhibit trapped gas; and a plurality of moveable diaphragms (13) each respectively provided in a respective of said pump cavities (7) for varying a volume of the pump cavities. The system further comprises a pump drive (31) which is configured to transfer a motion to the diaphragms (13) of the pump head (1; 101; 201) for accomplishing a fluid displacement from the common inlet (3) to the common outlet (5) of the pump head (1; 101; 201; 301) as a result of said varying of the volume of the pump cavities (7).
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公开(公告)号:US20210222681A1
公开(公告)日:2021-07-22
申请号:US16645022
申请日:2018-09-06
申请人: Cytiva Sweden AB
发明人: Andreas Torbjorn Lundin , Klas Marteleur , Mats Lundkvist , Andreas Marcstrom , David Gronowitz
摘要: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).
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