公开(公告)号：US20240017252A1

公开(公告)日：2024-01-18

申请号：US18475121

申请日：2023-09-26

Applicant: Cytiva Sweden AB

Inventor： Tuomo Valtteri Frigard ,  Robert Magnusson ,  Mats Lundkvist ,  Karl Axel Jakob Liderfelt ,  Helena Nordvarg ,  Andreas Torbjorn Lundin ,  Peter Arne Reffner

IPC: B01L3/00 ,  B01D15/10 ,  B01D61/14

CPC classification number: B01L3/502715 ,  B01D15/10 ,  B01D61/145 ,  B01L3/502738 ,  B01L3/502761 ,  B01D2311/2626 ,  B01D2315/16 ,  B01L2200/028 ,  B01L2200/0647 ,  B01L2300/0627 ,  B01L2300/0809 ,  B01L2300/0864 ,  B01L2400/06

Abstract: Disclosed is a modular bio-processing unit comprising: a housing having one or more internal fluid paths, the housing having at least one inlet and at least one outlet, each in fluid communication with the fluid path or one or more of the fluid paths; one or more sensor elements operatively associated with the or each path, said sensor(s) elements including elements of one or more of: a flow sensor, a flow rate sensor, a conductivity sensor, a pressure sensor, a pH sensor, and a light absorbance sensor such as a UV spectroscopic concentration sensor; one or more fluid flow inducing components operatively associated with the or each fluid path; and plural valves for preventing or reducing flow in the or each path, the housing, inlet(s), outlet(s), flow inducing component(s) and valve(s) being arranged to operate together as a bio-processing unit within or substantially within the housing.

公开(公告)号：US12017215B2

公开(公告)日：2024-06-25

申请号：US16486736

申请日：2018-02-27

Applicant: Cytiva Sweden AB

Inventor： Tuomo Valtteri Frigard ,  Robert Magnusson ,  Mats Lundkvist ,  Karl Axel Jakob Liderfelt ,  Helena Nordvarg ,  Andreas Torbjorn Lundin ,  Peter Arne Reffner

IPC: B01L3/00 ,  B01D15/10 ,  B01D61/14

CPC classification number: B01L3/502715 ,  B01D15/10 ,  B01D61/145 ,  B01L3/502738 ,  B01L3/502761 ,  B01D2311/2626 ,  B01D2315/16 ,  B01L2200/028 ,  B01L2200/0647 ,  B01L2300/0627 ,  B01L2300/0809 ,  B01L2300/0864 ,  B01L2400/06

Abstract: Disclosed is a modular bio-processing unit (100) comprising: a housing (110) having one or more internal fluid paths (101), the housing having at least one inlet and at least one outlet (5,10,15,20,25,30,35,40,45,50,55,60,65,70), each in fluid communication with the fluid path or one or more of the fluid paths; one or more sensor elements (120,150,170,190) operatively associated with the or each path, said sensor(s) elements including elements of one or more of: a flow sensor, a flow rate sensor, a conductivity sensor, a pressure sensor, a pH sensor, and a light absorbance sensor such as a UV spectroscopic concentration sensor; one or more fluid flow inducing components (140) operatively associated with the or each fluid path; and plural valves (180) for preventing or reducing flow in the or each path, the housing, inlet(s), outlet(s), flow inducing component(s) and valve(s) being arranged to operate together as a bio-processing unit within or substantially within the housing.

公开(公告)号：US20230333098A1

公开(公告)日：2023-10-19

申请号：US18317411

申请日：2023-05-15

Applicant: Cytiva Sweden AB

Inventor： Ola Lind ,  Johan Fredrik Avallin ,  Andreas Torbjorn Lundin ,  Nils Norrman ,  Ronnie Palmgren ,  Gustav Jose Rodrigo

IPC: G01N33/543 ,  C12M3/06 ,  B03C1/30 ,  C12M1/00 ,  C12M3/00 ,  B01D21/00 ,  C12N13/00 ,  B03C5/00 ,  B03C5/02 ,  C12M1/34 ,  B03C1/28 ,  B03C1/01

CPC classification number: G01N33/54326 ,  C12M27/16 ,  B03C1/30 ,  C12M45/07 ,  C12M23/48 ,  B01D21/0009 ,  C12M47/04 ,  C12N13/00 ,  C12M47/10 ,  B03C5/00 ,  C12M29/00 ,  B03C5/02 ,  C12M41/44 ,  G01N33/5436 ,  B03C1/288 ,  B03C1/01 ,  G01N2333/31 ,  B03C2201/26

Abstract: A separation system, and an elution arrangement to be provided in a separation system, for separating a biomolecule from a cell culture are provided.

公开(公告)号：US20240018952A1

公开(公告)日：2024-01-18

申请号：US18465810

申请日：2023-09-12

Applicant: Cytiva Sweden AB

Inventor： Andreas Torbjorn Lundin ,  Klas Marteleur ,  Mats Lundkvist ,  Andreas Marcstrom ,  David Gronowitz

IPC: F04B1/047 ,  F04B43/02

CPC classification number: F04B1/047 ,  F04B43/026 ,  F04B43/02

Abstract: A multiple cavity reciprocating positive displacement pump comprising plural pump cavities each including at least one pair of one-way valves the at least one pair including an inlet valve and an outlet valve, the pump being characterised in that respective inlet valves are in fluid communication with a common inlet and respective outlet valves are in fluid communication with a common outlet. The multiple cavities may include diaphragm arranged in a radial configuration for more uniform pressure output.

公开(公告)号：US11815075B2

公开(公告)日：2023-11-14

申请号：US16645022

申请日：2018-09-06

Applicant: Cytiva Sweden AB

Inventor： Andreas Torbjorn Lundin ,  Klas Marteleur ,  Mats Lundkvist ,  Andreas Marcstrom ,  David Gronowitz

IPC: F04B1/047 ,  F04B43/02

CPC classification number: F04B1/047 ,  F04B43/02 ,  F04B43/026

Abstract: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).

公开(公告)号：US20210222681A1

公开(公告)日：2021-07-22

申请号：US16645022

申请日：2018-09-06

Applicant: Cytiva Sweden AB

Inventor： Andreas Torbjorn Lundin ,  Klas Marteleur ,  Mats Lundkvist ,  Andreas Marcstrom ,  David Gronowitz

IPC: F04B1/047 ,  F04B43/02

Abstract: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).

公开(公告)号：US10954939B2

公开(公告)日：2021-03-23

申请号：US15769818

申请日：2016-10-28

Applicant: Cytiva Sweden AB

Inventor： Andreas Torbjorn Lundin

IPC: F04C2/08 ,  F04C15/00 ,  F04C2/18

Abstract: Disclosed is a gear pump (10) comprising a contra rotating gear element pair (30 and 40) mounted within a housing (20), each gear element having complementary gear teeth sets providing a pumping action in use, said teeth being formed from an annulus (34 and 44) of generally rigid construction mounted on a relatively flexible inner section (35 and 45), the gear pair being mounted such that their respective annuli are biased into resilient contact with the housing to provide a sliding seal.