公开(公告)号：US11643627B2

公开(公告)日：2023-05-09

申请号：US16474626

申请日：2017-12-27

Applicant: CYTIVA SWEDEN AB

Inventor： Klaus Gebauer ,  Nagaraj Raghavendra Rao ,  Anindya Kanti De ,  Anindya Sengupta ,  Mats Olsson ,  Colin R. Tuohey ,  Jonathan A. Kenney ,  Richard Lee Damren ,  Ralph Stankowski ,  Nirmal Kumar Thanikachalam

IPC: C12M1/00 ,  C12M3/00

CPC classification number: C12M23/14 ,  C12M23/26 ,  C12M23/28 ,  C12M23/48

Abstract: A support housing for a flexible bioprocess bag, the housing comprising at least one side wall having a first segment and a second segment, the first segment movable in relation to the second segment between an open and a closed position, wherein at least a supporting part of the housing is translatable from an operating position to a bag loading position, wherein the supporting part comprises one or more retainers for holding the flexible bioprocess bag upon re-translation of the supporting part to the operating position and movement of the first segment to the closed position, and wherein the first segment comprises a first drive unit for connecting and driving a first mixing unit in the flexible bioprocess bag.

公开(公告)号：US20220275317A1

公开(公告)日：2022-09-01

申请号：US17763135

申请日：2020-09-30

Applicant: Cytiva Sweden AB

Inventor： Klas Marteleur ,  Andreas Marcstrom ,  Mats Olsson ,  Klaus Gebauer

IPC: C12M1/12 ,  C12M1/00 ,  C12M1/36 ,  B33Y80/00

Abstract: Disclosed is a bioprocess system (1) comprising a flow path (3; 3a, 3) comprising: a plurality of inlets (7); at least one bio-processing device inlet connection (9a) and at least one bioprocessing device outlet connection (9b); a plurality of outlets (11); and flow path parts (5a′, 5b′, 5c′, 5d′, 5e′) of at least some active components (5a, 5b, 5c, 5d, 5e) comprised in the bioprocess system; and active parts (5a″, 5b″, 5c″, 5d″, 5e″) of said active components (5a, 5b, 5c, 5d, 5e). The flow path (3; 3a, 3b) of the bioprocess system is positioned centrally within the bioprocess system (1) and in a vertical orientation, whereby the active parts (5a″, 5b″, 5c″, 5d″, 5e″) are positioned around the flow path (3; 3a, 3b) being accessible from outside the bioprocess system (1) and each in connection with a corresponding flow path part (5a′, 5b′, 5c′, 5d′, 5e′) of an active component (5a, 5b, 5c, 5d, 5e).

公开(公告)号：US11466241B2

公开(公告)日：2022-10-11

申请号：US15781217

申请日：2016-11-25

Applicant: CYTIVA SWEDEN AB

Inventor： Amit Kumar Singh ,  Klaus Gebauer ,  Supti Datta ,  Jakob Liderfelt ,  Nachiket Karmarkar ,  Ajit S. Vernekar ,  Mats Olsson ,  Rajan Thiyaga ,  Amit K. Sharma ,  Sasi Kumar Nutalapati ,  Fredrik Lundstrom ,  Jean Pierre Neff

IPC: C12M1/00 ,  B01D15/08 ,  B01D61/18 ,  C12M1/34

Abstract: The invention discloses a first unit (1) for treatment of a bioprocess liquid comprising a first lateral face (2), a second lateral face (3) and a front face (4) which meets the two said lateral faces. The front face comprises: a plurality of valves (7) adapted to receive and act upon one or more legs (8) of a disposable flow path (6); optionally one or more pumps (10) adapted to receive and act upon one or more legs of the disposable flow path; optionally one or more sensors (11) adapted to receive and to measure one or more parameters in one or more legs of the disposable flow path; wherein the plurality of valves and optional pumps and sensors are vertically offset from each other to give one or more legs of a disposable flow path received by said valves and optional pumps and sensors a slope of at least 3.0 degrees from the horizontal plane (h).