公开(公告)号：US20230310693A1

公开(公告)日：2023-10-05

申请号：US18022018

申请日：2021-08-19

Applicant: CYTOSORBENTS CORPORATION

Inventor： Phillip P. CHAN ,  Ophir ORTIZ ,  Thomas D. Golobish ,  Vincent J. CAPPONI ,  Wei-Tai Young

IPC: A61L15/44 ,  A61L15/42 ,  A61L15/38

CPC classification number: A61L15/44 ,  A61L15/425 ,  A61L15/38 ,  A61L2300/254 ,  A61L2300/43 ,  A61L2300/402 ,  A61L2300/414

Abstract: The invention concerns methods for the selective, topical or trans dermal delivery or removal of one or more substances to, or from, respectively, the skin or surface of a human or animal subject, via the topical or transdermal application of a porous, polymeric composition capable of releasing or sorbing (adsorbing and/or absorbing) said substances, wherein said porous polymer is a particulate material, with particles having an average diameter in the range of approximately 0.1 microns to approximately 0.5 centimeters, and having a plurality of pores with an average pore diameter in a range of approximately 50 Angstroms to approximately 40,000 Angstroms.

公开(公告)号：US20170216345A1

公开(公告)日：2017-08-03

申请号：US15515328

申请日：2015-10-02

Applicant: CYTOSORBENTS CORPORATION

Inventor： Humayra Begum ALI ,  Thomas D. GOLOBISH ,  Vincent J. CAPPONI ,  Phillip P. CHAN ,  Wei-Tai YOUNG ,  Andrew Robert SCHEIRER

IPC: A61K31/765 ,  A61K9/00

CPC classification number: A61K31/765 ,  A61K9/0053 ,  A61K31/75 ,  A61K31/79 ,  A61P1/00 ,  A61P1/04 ,  A61P1/06

Abstract: Disclosed herein are compositions and methods for preventing or treating acute or chronic oral mucositis, esophagitis, enteritis, colitis, or gastrointestinal acute radiation syndrome (GI-ARS) caused by radiation exposure, using one or more enteron sorbent polymers administered gastrointestinally (e.g. orally, via feeding or gastric tube, via ostomy, or rectally).

公开(公告)号：US20250009951A1

公开(公告)日：2025-01-09

申请号：US18713370

申请日：2022-11-29

Applicant: CYTOSORBENTS CORPORATION

Inventor： Phillip P. CHAN ,  Karl-Gustav RUGGEBERG ,  Ritu TRIPATHI ,  Ophir ORTIZ ,  Richard R. MCKAY

IPC: A61M1/36 ,  B01J20/26 ,  B01J20/28

Abstract: Methods of treating cancer in a subject by administering a therapeutically effective amount of a porous biocompatible sorbent are disclosed. The porous biocompatible sorbents comprise a range of pore diameters between about 50 Å to about 40,000 Å and a pore volume between about 0.5 cc/g to about 5.0 cc/g dry polymer.

公开(公告)号：US20230310493A1

公开(公告)日：2023-10-05

申请号：US18320417

申请日：2023-05-19

Applicant: CYTOSORBENTS CORPORATION

Inventor： Andreas Viktor SIMM ,  Jorg SCHEIER ,  Christian STEINER ,  Vincent CAPPONI ,  Phillip P. CHAN

IPC: A61K31/79 ,  A61K31/717 ,  A61K31/78

CPC classification number: A61K31/79 ,  A61K31/717 ,  A61K31/78

Abstract: The invention concerns removing advanced glycation end products from a bodily fluid by contacting the bodily fluid with a sorbent.