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公开(公告)号:US20230310693A1
公开(公告)日:2023-10-05
申请号:US18022018
申请日:2021-08-19
Applicant: CYTOSORBENTS CORPORATION
Inventor: Phillip P. CHAN , Ophir ORTIZ , Thomas D. Golobish , Vincent J. CAPPONI , Wei-Tai Young
CPC classification number: A61L15/44 , A61L15/425 , A61L15/38 , A61L2300/254 , A61L2300/43 , A61L2300/402 , A61L2300/414
Abstract: The invention concerns methods for the selective, topical or trans dermal delivery or removal of one or more substances to, or from, respectively, the skin or surface of a human or animal subject, via the topical or transdermal application of a porous, polymeric composition capable of releasing or sorbing (adsorbing and/or absorbing) said substances, wherein said porous polymer is a particulate material, with particles having an average diameter in the range of approximately 0.1 microns to approximately 0.5 centimeters, and having a plurality of pores with an average pore diameter in a range of approximately 50 Angstroms to approximately 40,000 Angstroms.
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公开(公告)号:US20170216345A1
公开(公告)日:2017-08-03
申请号:US15515328
申请日:2015-10-02
Applicant: CYTOSORBENTS CORPORATION
Inventor: Humayra Begum ALI , Thomas D. GOLOBISH , Vincent J. CAPPONI , Phillip P. CHAN , Wei-Tai YOUNG , Andrew Robert SCHEIRER
IPC: A61K31/765 , A61K9/00
CPC classification number: A61K31/765 , A61K9/0053 , A61K31/75 , A61K31/79 , A61P1/00 , A61P1/04 , A61P1/06
Abstract: Disclosed herein are compositions and methods for preventing or treating acute or chronic oral mucositis, esophagitis, enteritis, colitis, or gastrointestinal acute radiation syndrome (GI-ARS) caused by radiation exposure, using one or more enteron sorbent polymers administered gastrointestinally (e.g. orally, via feeding or gastric tube, via ostomy, or rectally).
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公开(公告)号:US20250009951A1
公开(公告)日:2025-01-09
申请号:US18713370
申请日:2022-11-29
Applicant: CYTOSORBENTS CORPORATION
Inventor: Phillip P. CHAN , Karl-Gustav RUGGEBERG , Ritu TRIPATHI , Ophir ORTIZ , Richard R. MCKAY
Abstract: Methods of treating cancer in a subject by administering a therapeutically effective amount of a porous biocompatible sorbent are disclosed. The porous biocompatible sorbents comprise a range of pore diameters between about 50 Å to about 40,000 Å and a pore volume between about 0.5 cc/g to about 5.0 cc/g dry polymer.
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公开(公告)号:US20230310493A1
公开(公告)日:2023-10-05
申请号:US18320417
申请日:2023-05-19
Applicant: CYTOSORBENTS CORPORATION
Inventor: Andreas Viktor SIMM , Jorg SCHEIER , Christian STEINER , Vincent CAPPONI , Phillip P. CHAN
IPC: A61K31/79 , A61K31/717 , A61K31/78
CPC classification number: A61K31/79 , A61K31/717 , A61K31/78
Abstract: The invention concerns removing advanced glycation end products from a bodily fluid by contacting the bodily fluid with a sorbent.
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