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公开(公告)号：US09907958B2
公开(公告)日：2018-03-06
申请号：US14790729
申请日：2015-07-02
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. , CALIFORNIA INSTITUTE OF TECHNOLOGY
发明人： Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Joel W. Burdick , Susan J. Harkema , Jonathan Hodes , Yu-Chong Tai , Mandheerej S. Nandra , Claudia A. Angeli , Thomas Anthony Desautels
CPC分类号： A61N1/36103 , A61H1/0237 , A61H1/0274 , A61N1/0551 , A61N1/0553 , A61N1/0556 , A61N1/36003 , A61N1/36153 , A63B21/00181 , A63B22/0235 , A63B69/0064 , A63B2213/004 , A63B2220/805 , A63B2230/60 , F04C2270/0421
摘要： Methods of enabling locomotor control, postural control, voluntary control of body movements (e.g., in non-weight bearing conditions), and/or autonomic functions in a human subject having spinal cord injury, brain injury, or neurological neuromotor disease are described.
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公开(公告)号：US20180229037A1
公开(公告)日：2018-08-16
申请号：US15878325
申请日：2018-01-23
申请人： The Regents of the University of California , California Institute of Technology , University of Louisville Research Foundation, Inc.
发明人： Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Joel W. Burdick , Susan J. Harkema , Jonathan Hodes , Yu-Chong Tai , Mandheerej S. Nandra , Claudia A. Angeli , Thomas Anthony Desautels
CPC分类号： A61N1/36103 , A61H1/0237 , A61H1/0274 , A61N1/0551 , A61N1/0553 , A61N1/0556 , A61N1/36003 , A61N1/36153 , A63B21/00181 , A63B22/0235 , A63B69/0064 , A63B2213/004 , A63B2220/805 , A63B2230/60 , F04C2270/0421
摘要： Methods comprising applying electrical stimulation to patients in conjunction with physical training are described.
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3.发明授权公开(公告)号：US09931508B2
公开(公告)日：2018-04-03
申请号：US15199580
申请日：2016-06-30
申请人： California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
发明人： Joel W. Burdick , Yu-Chong Tai , John F. Naber , Robert S. Keynton , Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Susan J. Harkema , Jonathan Hodes , Claudia A Angeli , Mandheerej S. Nandra , Thomas Anthony Desautels , Steven L. Upchurch , Douglas J. Jackson , Nicholas A. Terrafranca , Yangsheng Chen
CPC分类号： A61N1/36103 , A61B5/0492 , A61B5/1106 , A61B5/407 , A61B5/4076 , A61B5/4836 , A61B2505/09 , A61N1/0551 , A61N1/0553 , A61N1/36003 , A61N1/36007 , A61N1/36067 , A61N1/36082 , A61N1/36107 , A61N1/3611 , A61N1/36114 , A61N1/36125 , A61N1/36139
摘要： Neurostimulator devices are described comprising: a stimulation assembly connectable to a plurality of electrodes, wherein the plurality of electrodes are configured to stimulate a spinal cord; one or more sensors; and at least one processor configured to modify at least one complex stimulation pattern deliverable by the plurality of electrodes by integrating data from the one or more sensors and performing a machine learning method implementing a Gaussian Process Optimization on the at least one complex stimulation pattern. Methods of use are also described.
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公开(公告)号：US11957910B2
公开(公告)日：2024-04-16
申请号：US17473406
申请日：2021-09-13
申请人： California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
发明人： Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Joel W. Burdick , Susan J. Harkema , Jonathan Hodes , Yu-Chong Tai , Mandheerej S. Nandra , Claudia A. Angeli , Thomas Anthony Desautels
CPC分类号： A61N1/36103 , A61H1/0237 , A61H1/0274 , A61N1/0551 , A61N1/0553 , A61N1/0556 , A61N1/36003 , A63B21/00181 , A61N1/3616 , A63B22/0235 , A63B69/0064 , A63B2213/004 , A63B2220/805 , A63B2230/60 , F04C2270/0421
摘要： Methods of enabling locomotor control, postural control, voluntary control of body movements (e.g., in non-weight bearing conditions), and/or autonomic functions in a human subject having a spinal cord injury, a brain injury, or a neurological neuromotor disease are described.
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公开(公告)号：US20180229038A1
公开(公告)日：2018-08-16
申请号：US15940473
申请日：2018-03-29
申请人： California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
发明人： Joel W. Burdick , Yu-Chong Tai , John F. Naber , Robert S. Keynton , Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Susan J. Harkema , Jonathan Hodes , Claudia A. Angeli , Mandheerej S. Nandra , Thomas Anthony Desautels , Steven L. Upchurch , Douglas J. Jackson , Nicholas A. Terrafranca, JR. , Yangsheng Chen
IPC分类号： A61N1/36 , A61N1/05 , A61B5/00 , A61B5/11 , A61B5/0492
CPC分类号： A61N1/36103 , A61B5/0492 , A61B5/1106 , A61B5/407 , A61B5/4076 , A61B5/4836 , A61B2505/09 , A61N1/0551 , A61N1/0553 , A61N1/36003 , A61N1/36007 , A61N1/36067 , A61N1/36082 , A61N1/36107 , A61N1/3611 , A61N1/36114 , A61N1/36125 , A61N1/36139
摘要： Neurostimulator devices are described. An example neurostimulator device includes a stimulation assembly connectable to a plurality of electrodes, wherein the plurality of electrodes are configured to stimulate a spinal cord. The neurostimulator device also includes an interface and at least one processor configured to modify at least one complex stimulation pattern deliverable by the plurality of electrodes by integrating data from the interface and performing a machine learning algorithm on the at least one complex stimulation pattern.
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公开(公告)号：US20210402186A1
公开(公告)日：2021-12-30
申请号：US17473406
申请日：2021-09-13
申请人： California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
发明人： Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Joel W. Burdick , Susan J. Harkema , Jonathan Hodes , Yu-Chong Tai , Mandheerej S. Nandra , Claudia A. Angeli , Thomas Anthony Desautels
摘要： Methods of enabling locomotor control, postural control, voluntary control of body movements (e.g., in non-weight bearing conditions), and/or autonomic functions in a human subject having a spinal cord injury, a brain injury, or a neurological neuromotor disease are described.
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公开(公告)号：US11116976B2
公开(公告)日：2021-09-14
申请号：US15878325
申请日：2018-01-23
申请人： The Regents of the University of California , California Institute of Technology , University of Louisville Research Foundation, Inc.
发明人： Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Joel W. Burdick , Susan J. Harkema , Jonathan Hodes , Yu-Chong Tai , Mandheerej S. Nandra , Claudia A. Angeli , Thomas Anthony Desautels
摘要： Methods comprising applying electrical stimulation to patients in conjunction with physical training are described.
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公开(公告)号：US10737095B2
公开(公告)日：2020-08-11
申请号：US15940473
申请日：2018-03-29
申请人： California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
发明人： Joel W. Burdick , Yu-Chong Tai , John F. Naber , Robert S. Keynton , Victor Reggie Edgerton , Roland R Roy , Yury Gerasimenko , Susan J. Harkema , Jonathan Hodes , Claudia A. Angeli , Mandheerej S. Nandra , Thomas Anthony Desautels , Steven L. Upchurch , Douglas J. Jackson , Nicholas A. Terrafranca, Jr. , Yangsheng Chen
IPC分类号： A61N1/36 , A61N1/05 , A61B5/00 , A61B5/0492 , A61B5/11
摘要： Neurostimulator devices are described. An example neurostimulator device includes a stimulation assembly connectable to a plurality of electrodes, wherein the plurality of electrodes are configured to stimulate a spinal cord. The neurostimulator device also includes an interface and at least one processor configured to modify at least one complex stimulation pattern deliverable by the plurality of electrodes by integrating data from the interface and performing a machine learning algorithm on the at least one complex stimulation pattern.
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公开(公告)号：US20160310739A1
公开(公告)日：2016-10-27
申请号：US15199580
申请日：2016-06-30
申请人： California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
发明人： Joel W. Burdick , Yu-Chong Tai , John F. Naber , Robert S. Keynton , Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Susan J. Harkema , Jonathan Hodes , Claudia A. Angeli , Mandheerej S. Nandra , Thomas Anthony Desautels , Steven L. Upchurch , Douglas J. Jackson , Nicholas A. Terrafranca , Yangsheng Chen
CPC分类号： A61N1/36103 , A61B5/0492 , A61B5/1106 , A61B5/407 , A61B5/4076 , A61B5/4836 , A61B2505/09 , A61N1/0551 , A61N1/0553 , A61N1/36003 , A61N1/36007 , A61N1/36067 , A61N1/36082 , A61N1/36107 , A61N1/3611 , A61N1/36114 , A61N1/36125 , A61N1/36139
摘要： Neurostimulator devices and methods of using these devices are described. The neurostimulator devices can include a stimulation assembly connectable to a plurality of electrodes; one or more sensors; and at least one processor configured to modify at least one complex stimulation pattern.
摘要翻译： 描述神经刺激装置和使用这些装置的方法。 神经刺激器装置可以包括可连接到多个电极的刺激组件; 一个或多个传感器; 以及配置成修改至少一个复杂刺激模式的至少一个处理器。
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公开(公告)号：US20150231396A1
公开(公告)日：2015-08-20
申请号：US14604625
申请日：2015-01-23
申请人： California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
发明人： Joel W. Burdick , Yu-Chong Tai , John F. Naber , Robert S. Keynton , Victor Reggie Edgerton , Roland R. Roy , Yury Gerasimenko , Susan J. Harkema , Johnathan Hodes , Claudia A. Angeli , Mandheerej S. Nandra , Thomas Anthony Desautels , Steven L. Upchurch , Douglas J. Jackson , Nicholas A. Terrafranca
IPC分类号： A61N1/36
CPC分类号： A61N1/36103 , A61B5/0492 , A61B5/1106 , A61B5/407 , A61B5/4076 , A61B5/4836 , A61B2505/09 , A61N1/0551 , A61N1/0553 , A61N1/36003 , A61N1/36007 , A61N1/36067 , A61N1/36082 , A61N1/36107 , A61N1/3611 , A61N1/36114 , A61N1/36125 , A61N1/36139
摘要： A neurostimulator devices and systems for use with groups of electrodes placed within a subject's body. The devices and systems can include training devices and/or pulse generation systems.
摘要翻译： 一种神经刺激器装置和系统，用于放置在受试者体内的电极组。 装置和系统可以包括训练装置和/或脉冲发生系统。
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