Method of making an article having a hemocompatible surface
    3.
    发明授权
    Method of making an article having a hemocompatible surface 失效
    制备具有血液相容性表面的制品的方法

    公开(公告)号:US5059269A

    公开(公告)日:1991-10-22

    申请号:US491020

    申请日:1990-03-09

    IPC分类号: A61L33/06 C08G18/61

    CPC分类号: C08G18/61 A61L33/068

    摘要: An article has a blood-contacting hemocompatible surface layer of a urethane-siloxane copolymer on a thermoplastic polymeric base material. The copolymer has siloxane segments prepared from hydroxyalkyl terminated polysiloxane glycols. The article is prepared by coextrusion of the base material and the copolymer.

    摘要翻译: 制品在热塑性聚合物基材上具有聚氨酯 - 硅氧烷共聚物的与血液接触的血液相容性表面层。 该共聚物具有由羟烷基封端的聚硅氧烷二醇制备的硅氧烷链段。 该制品通过共挤出基材和共聚物制备。

    Amine rich fluorinated polyurethaneureas and their use in a method to
immobilize an antithrombogenic agent on a device surface
    5.
    发明授权
    Amine rich fluorinated polyurethaneureas and their use in a method to immobilize an antithrombogenic agent on a device surface 失效
    富胺氟化聚氨酯脲及其在将抗血栓形成剂固定在器械表面上的方法中的用途

    公开(公告)号:US5077372A

    公开(公告)日:1991-12-31

    申请号:US672245

    申请日:1991-03-20

    IPC分类号: A61L33/00 C08G18/12 C08G18/50

    摘要: A thermoplastic polyurethaneurea having free amino groups is the reaction product of a diisocyanate, a fluorinated polyol, a non-fluorinated polyol and a polyamine. The invention includes a shaped polymeric support structure having the thermoplastic polyurethaneurea coated thereon and a medical article comprising the coated support and heparin covalently bonded to the free amino groups of the coated support. In another aspect of the invention, a method for preparing the heparinized medical article is provided.

    摘要翻译: 具有游离氨基的热塑性聚氨酯脲是二异氰酸酯,氟化多元醇,非氟化多元醇和多胺的反应产物。 本发明包括具有涂覆在其上的热塑性聚氨酯脲的成形聚合物支撑结构和包含共价结合到涂覆的载体的游离氨基的涂覆的载体和肝素的医疗制品。 在本发明的另一方面,提供了一种制备肝素化医疗用品的方法。

    Polymeric articles having enhanced antithrombogenic activity
    9.
    发明授权
    Polymeric articles having enhanced antithrombogenic activity 失效
    具有增强的抗血栓形成活性的聚合物制品

    公开(公告)号:US4720512A

    公开(公告)日:1988-01-19

    申请号:US843323

    申请日:1986-03-24

    摘要: Plastic articles having enhanced antithrombogenic activity due to the presence of hydrophobic materials attached to amine compounds bonded on the surface of the plastic which repel bonded antithrom bogenic agents outwardly from the plastic surface, making them more readily available to the blood for subsequent thrombus inhibition.

    摘要翻译: 塑料制品具有增强的抗血栓形成活性,因为存在与粘附在塑料表面上的胺化合物连接的疏水性材料,其从塑料表面向外排斥结合的抗血栓形成剂,使得它们更容易获得血液​​用于随后的血栓抑制。

    Intraocular Lens Insertion Devices
    10.
    发明申请
    Intraocular Lens Insertion Devices 有权
    眼内透镜插入装置

    公开(公告)号:US20110295264A1

    公开(公告)日:2011-12-01

    申请号:US12753762

    申请日:2010-04-02

    IPC分类号: A61F9/00

    摘要: A cartridge for an intraocular lens insertion device is disclosed. An example cartridge may include an intraocular lens insertion cartridge body having a distal end and a proximal end and configured to receive an intraocular lens for insertion into a patient's eye through an incision; the intraocular lens insertion cartridge body having an inner surface comprising at least one polymeric material having a hardness greater than about 50 D and an elongation at break greater than about 150%; the inner surface of the intraocular lens insertion cartridge body defining an at least partially tapering insertion pathway disposed within the intraocular lens insertion cartridge body and extending from the proximal end to the distal end of the intraocular lens insertion cartridge body.

    摘要翻译: 公开了一种用于眼内透镜插入装置的盒。 示例性盒可以包括眼内透镜插入盒本体,其具有远端和近端并且被配置为接收通过切口插入患者眼睛的眼内透镜; 所述眼内透镜插入筒体具有包含至少一种硬度大于约50D且断裂伸长率大于约150%的至少一种聚合材料的内表面; 眼内透镜插入盒本体的内表面限定设置在眼内透镜插入盒本体内并从眼内透镜插入筒体的近端延伸到远端的至少部分渐缩的插入通道。