摘要:
Melt processable polyurethaneureas are prepared from a diisocyanate, a macroglycol, a diol chain extender and a diamine chain extender. Water may be included as a reactant, and the polymer may contain an additive such as a radiopaque material. The invention includes a one-pot bulk polymerization method for preparation of the polymers.
摘要:
An article has a blood-contacting hemocompatible surface layer of a urethane-siloxane copolymer on a thermoplastic polymeric base material. The copolymer has siloxane segments prepared from hydroxyalkyl terminated polysiloxane glycols. The article is prepared by coextrusion of the base material and the copolymer.
摘要:
A thermoplastic polyurethaneurea having free amino groups is the reaction product of a diisocyanate, a fluorinated polyol, a non-fluorinated polyol and a polyamine. The invention includes a shaped polymeric support structure having the thermoplastic polyurethaneurea coated thereon and a medical article comprising the coated support and heparin covalently bonded to the free amino groups of the coated support. In another aspect of the invention, a method for preparing the heparinized medical article is provided.
摘要:
A thermoplastic polyurethaneurea having free amino groups is the reaction product of a diisocyanate, a fluorinated polyol, a non-fluorinated polyol and a polyamine. The invention includes a shaped polymeric support structure having the thermoplastic polyurethaneurea coated thereon and a medical article comprising the coated support and heparin covalently bonded to the free amino groups of the coated support. In another aspect of the invention, a method for preparing the heparinized medical article is provided.
摘要:
A method for heparinizing a substrate includes applying a coating of ammonium salt to a substrate by steeping the substrate in a solution of the salt at an alkaline pH and contacting the coated substrate with a solution of a salt of heparin.
摘要:
Plastic articles having enhanced antithrombogenic activity due to the presence or hydrophobic materials attached to amine compounds bonded on the surface of the plastic which repel bonded antithrombogenic agents outwardly from the plastic surface, making them more readily available to the blood for subsequent thrombus inhibition.
摘要:
An article has a blood-contacting hemocompatible surface layer of a urethane-siloxane copolymer on a thermoplastic polymeric base material. The copolymer has siloxane segments prepared from hydroxyalkyl terminated polysiloxane glycols. The article is prepared by coextrusion of the base material and the copolymer.
摘要:
A method for lubricating a low surface energy polymeric surface includes plasma treatment of the surface. A film of a polysiloxane lubricant is applied to the plasma-treated surface to give an even coating of the lubricant which is stable for a protracted period of time.
摘要:
Plastic articles having enhanced antithrombogenic activity due to the presence of hydrophobic materials attached to amine compounds bonded on the surface of the plastic which repel bonded antithrom bogenic agents outwardly from the plastic surface, making them more readily available to the blood for subsequent thrombus inhibition.
摘要:
A cartridge for an intraocular lens insertion device is disclosed. An example cartridge may include an intraocular lens insertion cartridge body having a distal end and a proximal end and configured to receive an intraocular lens for insertion into a patient's eye through an incision; the intraocular lens insertion cartridge body having an inner surface comprising at least one polymeric material having a hardness greater than about 50 D and an elongation at break greater than about 150%; the inner surface of the intraocular lens insertion cartridge body defining an at least partially tapering insertion pathway disposed within the intraocular lens insertion cartridge body and extending from the proximal end to the distal end of the intraocular lens insertion cartridge body.