METHODS AND SYSTEMS FOR CONTINUOUS FLOW CELL LYSIS IN A MICROFLUIDIC DEVICE
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    发明申请
    METHODS AND SYSTEMS FOR CONTINUOUS FLOW CELL LYSIS IN A MICROFLUIDIC DEVICE 审中-公开
    微流控器件中连续流量池的方法与系统

    公开(公告)号:US20150184127A1

    公开(公告)日:2015-07-02

    申请号:US14586576

    申请日:2014-12-30

    摘要: The present invention relates to methods and systems for cell lysis in a microfluidic device. More specifically, embodiments of the present invention relate to methods and systems for rapid continuous flow mechanical cell lysis. In one embodiment, a microfluidic device includes one or more microfluidic channels, each channel comprising constricted regions and non-constricted regions separating the constricted regions, wherein the constricted regions are configured to disrupt the cellular membranes of cells in fluid flowing through the one or more microfluidic channels.

    摘要翻译: 本发明涉及微流控装置中细胞裂解的方法和系统。 更具体地,本发明的实施方案涉及用于快速连续流动机械细胞裂解的方法和系统。 在一个实施例中,微流体装置包括一个或多个微流体通道,每个通道包括收缩区域和分离收缩区域的非收缩区域,其中缩小区域被配置为破坏流过该一个或多个流体的流体中的细胞的细胞膜 微流体通道。

    Methods and systems for continuous flow cell lysis in a microfluidic device

    公开(公告)号:US10137673B2

    公开(公告)日:2018-11-27

    申请号:US14586576

    申请日:2014-12-30

    摘要: The present invention relates to methods and systems for cell lysis in a microfluidic device. More specifically, embodiments of the present invention relate to methods and systems for rapid continuous flow mechanical cell lysis. In one embodiment, a microfluidic device includes one or more microfluidic channels, each channel comprising constricted regions and non-constricted regions separating the constricted regions, wherein the constricted regions are configured to disrupt the cellular membranes of cells in fluid flowing through the one or more microfluidic channels.