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    DELIVERY SYSTEM FOR VASCULAR IMPLANT
    1.
    发明申请
    DELIVERY SYSTEM FOR VASCULAR IMPLANT 有权
    用于血管植入的输送系统

    公开(公告)号：US20150081009A1

    公开(公告)日：2015-03-19

    申请号：US14551338

    申请日：2014-11-24

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： Arshad Quadri ,  J. Brent Ratz

    IPC: A61F2/95

    CPC classification number: A61F2/246 ,  A61F2/2418 ,  A61F2/243 ,  A61F2/2439 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0067

    Abstract: A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.

    Abstract translation: 描述了一种治疗系统和治疗方法，其具有能够定位和展开的植入物，然后去除部署以允许植入物的重新定位。 该系统包括自动扩张的医用植入物，其在从径向压实状态径向膨胀时纵向缩短，构造成将植入物附接到输送装置的远端安装件的远端界面，以及被配置为将植入物附接到近端 输送装置的安装。 将远端安装件纵向远离近侧安装件移动，对植入物施加纵向张力，使得植入物纵向膨胀并径向收缩，并使远端安装件向近端安装件移动，减小了植入物中的纵向张力，使植入物径向扩张 一个完全扩张的状态。

    VASCULAR IMPLANT AND DELIVERY METHOD
    2.
    发明申请
    VASCULAR IMPLANT AND DELIVERY METHOD 有权
    血管植入和输送方法

    公开(公告)号：US20150066140A1

    公开(公告)日：2015-03-05

    申请号：US14538638

    申请日：2014-11-11

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： Arshad Quadri ,  J. Brent Ratz

    IPC: A61F2/24

    CPC classification number: A61F2/2409 ,  A61F2/24 ,  A61F2/2418 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2002/9522 ,  A61F2002/9534 ,  A61F2220/0016 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2250/001

    Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.

    Abstract translation: 用于替换天然心脏瓣膜的血管植入物包括支撑具有传单的阀体的自扩张支架。 支架优选地包括构造成防止植入物通过瓣膜环的锚定结构。 为了交付，植入物在输送装置内压实并固定在一端。 在输送期间，植入物部分地从输送装置释放，并且可以在完全释放之前验证植入物的定位。 如果需要，植入物可以至少部分地重新固定并重新定位。

    VASCULAR IMPLANT
    3.
    发明申请
    VASCULAR IMPLANT 有权
    血管植入

    公开(公告)号：US20140309731A1

    公开(公告)日：2014-10-16

    申请号：US14313160

    申请日：2014-06-24

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： Arshad Quadri ,  J. Brent Ratz

    IPC: A61F2/24

    CPC classification number: A61F2/2409 ,  A61F2/24 ,  A61F2/2418 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2002/9522 ,  A61F2002/9534 ,  A61F2220/0016 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2250/001

    Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.

    Abstract translation: 用于替换天然心脏瓣膜的血管植入物包括支撑具有传单的阀体的自扩张支架。 支架优选地包括构造成防止植入物通过瓣膜环的锚定结构。 为了交付，植入物在输送装置内压实并固定在一端。 在输送期间，植入物部分地从输送装置释放，并且可以在完全释放之前验证植入物的定位。 如果需要，植入物可以至少部分地重新固定并重新定位。

    Replacement heart valve and method
    5.
    发明授权
    Replacement heart valve and method 有权
    更换心脏瓣膜及方法

    公开(公告)号：US08894702B2

    公开(公告)日：2014-11-25

    申请号：US13747384

    申请日：2013-01-22

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： Arshad Quadri ,  J. Brent Ratz

    IPC: A61F2/848 ,  A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2403 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/848 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2210/0076 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2230/0054 ,  Y10T29/49426

    Abstract: A method of treating a native heart valve includes delivering a replacement valve to the native heart valve. The native heart valve can be any one of aortic, pulmonary, mitral and tricuspid valves. The replacement valve comprising an expandable frame and a valve body attached to the expandable frame. The method can also include expanding the frame at a patient's valve annulus, wherein expansion of the frame causes respective ends of both proximal anchors and distal anchors connected to the frame to draw closer together to grasp native tissue between the respective ends of the proximal anchors and distal anchors.

    Abstract translation: 治疗天然心脏瓣膜的方法包括向天然心脏瓣膜递送置换瓣膜。 天然心脏瓣膜可以是主动脉瓣，肺动脉，二尖瓣和三尖瓣中的任何一个。 替换阀包括可膨胀框架和连接到可膨胀框架的阀体。 该方法还可以包括在患者的瓣膜环上扩大框架，其中，框架的扩张引起两个近端锚固件和连接到框架的远端锚固件的相应端部以更靠近地拉近，以抓住近端锚固件的相应端部之间的天然组织和 远端锚。

    PROSTHESIS FOR ATRAUMATICALLY GRASPING INTRALUMENAL TISSUE AND METHODS OF DELIVERY
    6.
    发明申请
    PROSTHESIS FOR ATRAUMATICALLY GRASPING INTRALUMENAL TISSUE AND METHODS OF DELIVERY 审中-公开
    用于ATRAUMATICALLY GRASPING INTRALUMENAL TISSUE的方法和方法

    公开(公告)号：US20140277427A1

    公开(公告)日：2014-09-18

    申请号：US14197690

    申请日：2014-03-05

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： J. Brent Ratz ,  Arshad Quadri ,  Luca Pesce

    IPC: A61F2/24

    CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2220/0008

    Abstract: A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the frame can have a larger cross-sectional dimension in a middle portion of the frame and a smaller cross-sectional dimension in a proximal portion and a distal portion of the frame, wherein the middle portion is between the proximal and distal portions. As another example, the anchors can have looped ends, the entire anchor may loop out from the frame.

    Abstract translation: 假体可以包括可扩张框架，多个远侧锚固件和多个近端锚固件。 锚杆可以从框架向外延伸。 框架可以被配置为径向扩张和收缩以在体腔内展开。 框架和锚可以具有许多不同形状和配置中的一种。 例如，当框架处于扩展构型时，框架可以在框架的中间部分具有较大的横截面尺寸，并且在框架的近端部分和远端部分中具有较小的横截面尺寸，其中， 中间部分在近端部分和远端部分之间。 作为另一示例，锚定器可以具有环形端部，整个锚定器可以从框架环出。

    Delivery system for vascular implant
    7.
    发明授权
    Delivery system for vascular implant 有权
    输血系统用于血管植入

    公开(公告)号：US08911455B2

    公开(公告)日：2014-12-16

    申请号：US13725896

    申请日：2012-12-21

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： Arshad Quadri ,  J. Brent Ratz

    IPC: A61B17/10 ,  A61F2/06 ,  A61F2/24 ,  A61F2/95

    CPC classification number: A61F2/246 ,  A61F2/2418 ,  A61F2/243 ,  A61F2/2439 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0067

    Abstract: A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.

    Abstract translation: 描述了一种治疗系统和治疗方法，其具有能够定位和展开的植入物，然后去除部署以允许植入物的重新定位。 该系统包括自动扩张的医用植入物，其在从径向压实状态径向膨胀时纵向缩短，构造成将植入物附接到输送装置的远端安装件的远端界面，以及被配置为将植入物附接到近端 输送装置的安装。 将远端安装件纵向远离近侧安装件移动，对植入物施加纵向张力，使得植入物纵向膨胀并径向收缩，并使远端安装件向近端安装件移动，减小了植入物中的纵向张力，使植入物径向扩张 一个完全扩张的状态。

    PROSTHESIS WITH OUTER SKIRT
    8.
    发明申请
    PROSTHESIS WITH OUTER SKIRT 有权
    与外套的外观

    公开(公告)号：US20140277422A1

    公开(公告)日：2014-09-18

    申请号：US14197639

    申请日：2014-03-05

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： J. Brent Ratz ,  Arshad Quadri ,  Luca Pesce

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2457 ,  A61F2220/0025 ,  A61F2230/0041 ,  A61F2230/0065

    Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity, and an outer skirt positioned annularly around an exterior of the expandable frame. In some embodiments, the outer skirt can extend outward from the frame and be secured to an outwardly extending anchor on the frame to create an axial barrier to fluid flow exterior to the frame when deployed within the body cavity.

    Abstract translation: 假体可以被构造成在部署在体腔内时抓住腔内组织，并且防止围绕假体外部的流体的轴向流动。 假体可以包括可扩张的框架，其被配置为径向地膨胀和收缩以在体腔内展开，以及环形地围绕可扩张框架的外部定位的外裙部。 在一些实施例中，外裙部可以从框架向外延伸并且被固定到框架上的向外延伸的锚固件，以在展开在体腔内时产生对框架外部的流体流动的轴向屏障。

    Vascular implant
    9.
    发明授权
    Vascular implant 有权
    血管植入

    公开(公告)号：US08795356B2

    公开(公告)日：2014-08-05

    申请号：US14186957

    申请日：2014-02-21

    Applicant: CardiAQ Valve Technologies, Inc.

    Inventor： Arshad Quadri ,  J. Brent Ratz

    IPC: A61F2/24

    CPC classification number: A61F2/2409 ,  A61F2/24 ,  A61F2/2418 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2002/9522 ,  A61F2002/9534 ,  A61F2220/0016 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2250/001

    Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.

    Abstract translation: 用于替换天然心脏瓣膜的血管植入物包括支撑具有传单的阀体的自扩张支架。 支架优选地包括构造成防止植入物通过瓣膜环的锚定结构。 为了交付，植入物在输送装置内压实并固定在一端。 在输送期间，植入物部分地从输送装置释放，并且可以在完全释放之前验证植入物的定位。 如果需要，植入物可以至少部分地重新固定并重新定位。

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