公开(公告)号：US07947112B1

公开(公告)日：2011-05-24

申请号：US12174099

申请日：2008-07-16

申请人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

发明人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

IPC分类号： B01D53/22

CPC分类号： B01D19/0063

摘要： A method for degassing a fluid includes providing a degassing system having a degassing module and a fluid pump apparatus having a fluid reservoir, wherein the fluid pump apparatus is operated in a discontinuous mode involving one or more discrete pumping cycles having a first cycle time. The fluid pump apparatus is calibrated to deliver a predetermined volume of the fluid from the fluid reservoir during each of the pumping cycles, and the degassing module is adapted to operably move gas from the fluid to an extent sufficient to render the fluid volume to a desired degassed condition within a period of time that is not greater than the first cycle time.

摘要翻译： 用于对流体进行脱气的方法包括提供具有脱气模块和具有流体储存器的流体泵装置的脱气系统，其中所述流体泵装置以包括具有第一循环时间的一个或多个离散泵送循环的不连续模式操作。 校准流体泵装置以在每个泵送循环期间从流体储存器输送预定体积的流体，并且脱气模块适于可操作地将气体从流体移动至足以使流体体积达到期望的程度 在不大于第一循环时间的时间段内的脱气条件。

公开(公告)号：US07259840B1

公开(公告)日：2007-08-21

申请号：US11051767

申请日：2005-02-04

申请人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

发明人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

IPC分类号： G01N1/00

CPC分类号： G01N21/05 ,  G01N2021/0346

摘要： A fluid analysis apparatus for containing and analyzing a fluid sample includes a cell body assembly having a plurality of distinct portions in fluid communication with one another and with the distinct portions being hydraulically sealed to one another through the use of one or more resilient gaskets interposed between adjacent ones of the plurality of distinct portions of the cell body assembly. The one or more resilient gaskets enable both hydraulic sealing of adjacent distinct portions, as well as fluid coupling and routing through the fluid analysis apparatus.

公开(公告)号：US07808619B2

公开(公告)日：2010-10-05

申请号：US11867806

申请日：2007-10-05

申请人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

发明人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

IPC分类号： G01N1/00

CPC分类号： G01N21/05 ,  G01N35/1095 ,  G01N2021/0346

摘要： A fluid analysis apparatus includes a cell body having a chamber disposed therein for containing fluid during analysis thereof. The chamber is specifically configured to operably and statically secure a radiant energy guiding member solely through surface-to-surface interaction.

摘要翻译： 流体分析装置包括具有设置在其中以用于在分析期间容纳流体的室的电池体。 腔室被特别地构造成仅通过表面到表面的相互作用可操作地和静态地固定辐射能量引导构件。

公开(公告)号：US07298472B2

公开(公告)日：2007-11-20

申请号：US11027456

申请日：2004-12-28

申请人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

发明人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

IPC分类号： G01N1/10

CPC分类号： G01N21/05 ,  G01N35/1095 ,  G01N2021/0346

摘要： A fluid analysis apparatus for containing and analyzing a fluid sample includes a cell body assembly having a plurality of distinct portions in fluid communication with one another and with the distinct portions being hydraulically sealed to one another through the use of one or more resilient gaskets interposed between adjacent ones of the plurality of distinct portions of the cell body assembly. The one or more resilient gaskets enable both hydraulic sealing of adjacent distinct portions, as well as fluid coupling and routing through the fluid analysis apparatus.

摘要翻译： 用于容纳和分析流体样品的流体分析装置包括具有多个彼此流体连通的不同部分的细胞体组件，并且不同部分通过使用一个或多个弹性垫圈彼此液压地密封 电池主体组件的多个不同部分中的相邻的部分。 一个或多个弹性垫圈能够实现相邻不同部分的液压密封，以及通过流体分析装置的流体联接和布线。

公开(公告)号：US07427312B2

公开(公告)日：2008-09-23

申请号：US11457386

申请日：2006-07-13

申请人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

发明人： Yuri Gerner ,  Carl W. Sims ,  Jonathan Thompson

IPC分类号： B01D53/22

CPC分类号： B01D19/0031

摘要： An apparatus for removing gas bubbles from a fluid includes a fluid inlet and a separation chamber that is in fluid communication with the fluid inlet. The separation chamber has first and second end portions, with the first end portion being operably oriented gravitationally above the second end portion. The apparatus further includes a first gas-permeable, liquid-impermeable membrane disposed in the separation chamber and extending substantially along a first axis defined as extending between the first and second end portions. A permeate side of the membrane is exposed to an environment having a second partial pressure of a target gas, which second partial pressure is lower than a first partial pressure of the gas in the fluid.

摘要翻译： 用于从流体中除去气泡的装置包括流体入口和与流体入口流体连通的分离室。 分离室具有第一和第二端部，其中第一端部可重力地在第二端部上方定向地定向。 该装置还包括设置在分离室中的第一透气性液体不可渗透膜，并且基本上沿着限定为在第一和第二端部之间延伸的第一轴延伸。 膜的渗透侧暴露于具有目标气体的第二分压的环境中，该第二分压低于流体中气体的第一分压。

公开(公告)号：US20080006578A1

公开(公告)日：2008-01-10

申请号：US11482369

申请日：2006-07-07

申请人： Carl W. Sims ,  Jonathan Thompson ,  Yuri Gerner

发明人： Carl W. Sims ,  Jonathan Thompson ,  Yuri Gerner

IPC分类号： C02F1/44

CPC分类号： G01N30/28 ,  B01D61/362 ,  B01D2311/13

摘要： A method for controlling pervaporation through a membrane includes assessing the vapor pressure of each component material of a mobile phase disposed on a retentate side of the membrane, and maintaining a designed environment on a permeate side of the membrane. The environment maintained on the permeate side of the membrane contains partial pressures of selected component materials of the mobile phase at a level substantially equal to or greater than the respective vapor pressures thereof.

摘要翻译： 用于控制通过膜的渗透蒸发的方法包括评估设置在膜的滞留侧上的流动相的每种组分材料的蒸汽压，并且在膜的渗透侧保持设计的环境。 保持在膜的渗透侧的环境包含流动相的所选组分材料的分压，其水平基本上等于或大于其各自的蒸气压。

公开(公告)号：US08017016B2

公开(公告)日：2011-09-13

申请号：US11482369

申请日：2006-07-07

申请人： Carl W. Sims ,  Jonathan Thompson ,  Yuri Gerner

发明人： Carl W. Sims ,  Jonathan Thompson ,  Yuri Gerner

IPC分类号： B01D15/00 ,  C02F1/44

CPC分类号： G01N30/28 ,  B01D61/362 ,  B01D2311/13

摘要： A method for controlling pervaporation through a membrane includes assessing the vapor pressure of each component material of a mobile phase disposed on a retentate side of the membrane, and maintaining a designed environment on a permeate side of the membrane. The environment maintained on the permeate side of the membrane contains partial pressures of selected component materials of the mobile phase at a level substantially equal to or greater than the respective vapor pressures thereof.

摘要翻译： 用于控制通过膜的渗透蒸发的方法包括评估设置在膜的滞留侧上的流动相的每种组分材料的蒸汽压，并且在膜的渗透侧保持设计的环境。 保持在膜的渗透侧的环境包含流动相的所选组分材料的分压，其水平基本上等于或大于其各自的蒸气压。

公开(公告)号：US06923908B1

公开(公告)日：2005-08-02

申请号：US10688617

申请日：2003-10-17

申请人： Jonathan Thompson ,  Yuri Gerner ,  Carl W. Sims

发明人： Jonathan Thompson ,  Yuri Gerner ,  Carl W. Sims

IPC分类号： B01D15/08 ,  B01D15/12 ,  G01N30/60

CPC分类号： B01D39/083 ,  B01D15/12 ,  B01D39/086 ,  B01D2239/0208 ,  B01D2239/1291 ,  G01N30/603

摘要： A filter apparatus for use in liquid chromatography systems includes a housing component having an open channel formed therethrough for operably receiving fluid transfer tubing in at least a first end thereof, a relatively thin mesh filter component, and a securement component configured to matingly engage with the housing such that the filter component is operably disposed and secured between the housing and the securement component adjacent to and superimposed over a second open end of the channel. The filter apparatus is thus adapted to operably filter chromatographic fluids being drawn through the channels from the second open end and into the fluid transfer tubing.

摘要翻译： 用于液相色谱系统的过滤装置包括壳体部件，其具有穿过其形成的开放通道，用于在其至少第一端中可操作地接收流体输送管，相对薄的网状过滤器部件和固定部件，其配置成与 壳体，使得过滤器部件可操作地设置并固定在壳体和固定部件之间，邻近并叠加在通道的第二开口端上。 因此，过滤装置适于可操作地过滤从第二开放端抽入通道的色谱流体并流入流体输送管。

公开(公告)号：US20120240769A1

公开(公告)日：2012-09-27

申请号：US13072422

申请日：2011-03-25

申请人： Yuri Gerner ,  Quan Liu ,  Carl W. Sims

发明人： Yuri Gerner ,  Quan Liu ,  Carl W. Sims

IPC分类号： B01D61/36 ,  B01D19/00

CPC分类号： B01D19/0063 ,  B01D19/0005 ,  B01D19/0031 ,  B01D19/0036 ,  B01D61/362 ,  B01D61/366 ,  B01D69/06 ,  B01D2313/19 ,  B01D2313/23

摘要： A liquid degassing apparatus is arranged to limit pervaporation through a membrane by establishing a pervaporation control space at a permeate side of the membrane. The pervaporation control space is defined in a vacuum chamber between the membrane and a shield member. The shield member may be substantially gas and liquid impermeable to maintain an environment in contact with the permeate side of the membrane that is relatively rich in solvent vapor concentration, thereby limiting further liquid pervaporation across the membrane.

摘要翻译： 液体脱气装置被布置成通过在膜的渗透侧建立渗透蒸发控制空间来限制通过膜的渗透。 在膜和屏蔽构件之间的真空室中限定渗透蒸发控制空间。 屏蔽构件可以基本上是气体和液体不可渗透的，以保持与膜的渗透侧接触的环境，其相对富含溶剂蒸气浓度，从而限制膜上的进一步液体渗透。

公开(公告)号：US09044712B2

公开(公告)日：2015-06-02

申请号：US13611420

申请日：2012-09-12

申请人： Carl W. Sims ,  Yuri Gerner ,  Quan Liu

发明人： Carl W. Sims ,  Yuri Gerner ,  Quan Liu

IPC分类号： B01D19/00 ,  B01D53/22 ,  B01D69/04 ,  B01D63/02 ,  B01D63/06 ,  B01D71/26 ,  B01D71/34 ,  B01D71/36

CPC分类号： B01D19/0031 ,  B01D63/02 ,  B01D63/06 ,  B01D71/26 ,  B01D71/34 ,  B01D71/36 ,  B01D2313/23

摘要： An elongated flow-through degassing apparatus includes an elongated gas permeable outer shell and one or more gas-permeable, liquid-impermeable elongated inner conveyance members extending within the outer shell and at least partially through a chamber defined within the outer shell. The apparatus also includes inlet and outlet junctions for securing the outer shell to the inner conveyance member. The outer shell exhibits a first permeance that is substantially greater than a second permeance of the inner conveyance member. The degassing apparatus may be sufficiently flexible so as to be readily manipulatable into desired configurations.

摘要翻译： 细长的流通脱气装置包括细长的可透气的外壳和一个或多个气体可渗透的液体不可渗透的细长内部传送构件，其在外壳内延伸并且至少部分地穿过限定在外壳内的室。 该装置还包括用于将外壳固定到内部输送构件的入口和出口接头。 外壳呈现出大体上大于内传送部件的第二渗透性的第一渗透。 脱气装置可以具有足够的柔性，以便容易地操纵成所需的构型。