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公开(公告)号：US12029486B2
公开(公告)日：2024-07-09
申请号：US17277177
申请日：2019-09-24
发明人： Jochen Straub , Robert Sprowl , Yuan Liu , Matthew J. Everett
CPC分类号： A61B3/12 , A61B3/0008 , A61B3/0033 , A61B3/158
摘要： A low cost fundus camera uses LED light sources placed adjacent the camera's imaging stop, and thereby eliminates the need for optics for introducing the light source to the camera's optical path. Lens reflex in the pupil relay is avoided by using only reflective optics in the pupil relay. Reflex from the LED is mitigated by actuating each LED separately, one at a time, and capturing a separate image with each actuated LED. Reflex-free regions of each captured image are extracted and combined to create a composite reflex-free image.
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2.发明授权公开(公告)号：US11499814B2
公开(公告)日：2022-11-15
申请号：US15734168
申请日：2019-06-12
申请人： Carl Zeiss Meditec, Inc. , Carl Zeiss AG , Carl Zeiss Industrial Metrology LLC , Carl Zeiss Meditec AG
IPC分类号： G01B11/02 , G01B9/02091 , G01N21/84 , A61B3/10
摘要： An optical coherence tomography (OCT) system (63) is used to inspect bonding points (66A, 66B, 66C) sandwiched between two materials (layers 62, 64 of e.g. displays). The OCT differentiates between a bonding point, e.g. a weld, and air gaps between the two materials. The bonding points are identified as breaks in the air gap between the materials. By extracting various physical characteristics of the bonding points and the gap between the two materials, the present system determines whether the bonding is faulty.
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公开(公告)号：US10799111B2
公开(公告)日：2020-10-13
申请号：US15311499
申请日：2015-06-09
IPC分类号： A61B3/10 , G01B9/02 , A61B3/12 , G01N21/47 , G02B21/00 , A61B3/00 , A61B3/15 , G02B27/09 , G01N21/45
摘要： Systems and methods for improved interferometric imaging are presented. One embodiment is a partial field frequency-domain interferometric imaging system in which a light beam is scanned in two directions across a sample and the light scattered from the object is collected using a spatially resolved detector. The light beam could illuminate a spot, a line or a two-dimensional area on the sample. Additional embodiments with applicability to partial field as well as other types of interferometric systems are also presented.
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公开(公告)号：US09706915B2
公开(公告)日：2017-07-18
申请号：US14861589
申请日：2015-09-22
CPC分类号： A61B3/102 , A61B3/0025 , A61B3/113 , A61B3/1233 , A61B5/0059 , A61B5/0066 , G01B9/02048 , G01B9/02077 , G01B9/02087 , G01B9/02091 , G01N21/4795 , G01N2021/1787
摘要： An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. Significant sample motion may occur during acquisition of the second set. A-scans from the first set are matched with A-scans from the second set, based on similarity between the longitudinal optical scattering profiles they contain. Such matched pairs of A-scans are likely to correspond to the same region in the sample. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair, in conjunction with any shift in the longitudinal scattering profiles between the pair of A-scans, reveals the displacement of the sample between acquisition of the first and second A-scans in the pair. Estimates of the sample displacement are used to correct the transverse and longitudinal coordinates of the A-scans in the second set, to form a motion-corrected OCT data set.
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5.发明授权Method and apparatus for measuring motion of a subject using a series of partial images from an imaging system 有权用于使用来自成像系统的一系列部分图像来测量对象的运动的方法和装置公开(公告)号：US09033504B2
公开(公告)日：2015-05-19
申请号：US14153993
申请日：2014-01-13
发明人： Matthew J. Everett , Claus Flachenecker , Martin Hacker , Scott A. Meyer , Keith E. O'Hara , Rick A. Williams
摘要： A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.
摘要翻译： 行扫描成像器用于确定被摄体的运动。 将来自行扫描成像器的每行图像数据与参考图像进行比较。 参考图像中匹配线的位置显示了被摄体的位移。 可以基于每行图像数据来确定当前被摄体位移。 所得到的位移信息可用于将其他光束正确地放置在被摄体上。 该方法可以应用于跟踪人眼以便于用光束照射进行测量，成像或处理。
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公开(公告)号：US10436573B2
公开(公告)日：2019-10-08
申请号：US15782018
申请日：2016-12-08
摘要： Various balanced detection systems which reduce alignment requirements of free space optics based balanced detection configurations are discussed. One example system includes a light source, a beam divider, sample optics, return optics, and a processor. The light source generates a light beam. The beam divider separates the light beam into reference and sample arms. The sample optics deliver the light beam in the sample arm to a light scattering object to be imaged. The return optics direct light to a balanced detection system, which has a balanced detection beam divider for combining light scattered from the object and light from the reference arm and directing the combined light into two detection channels and two detectors for collecting the combined light in the two detection channels and generating signals in response thereto. The processor processes the signals and generates image data of the object based on the processed signals.
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公开(公告)号：US09778018B2
公开(公告)日：2017-10-03
申请号：US14613121
申请日：2015-02-03
发明人： Tilman Schmoll , Matthew J. Everett
CPC分类号： G01B9/02004 , A61B3/102 , G01B9/02005 , G01B9/02077 , G01B9/02091
摘要： Embodiments herein include swept-source interferometric imaging systems employing arbitrary sweep patterns in which a swept-source is swept over a continuous spectral range where the variation of wavelength over time is noncontinuous. Embodiments include sweep patterns that result in reduction of signals from moving scatterers and where the sweep is synchronized with the dead time of the camera.
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公开(公告)号：US10571243B2
公开(公告)日：2020-02-25
申请号：US16075934
申请日：2017-02-10
摘要： Various systems and methods for sequential angle illumination to achieve ultra-high resolution optical coherence tomography (OCT) images. One example OCT system includes a light source, a beam divider, sample arm optics, a detector, and a processor. The light source generates a light beam to illuminate the sample. The beam divider separates the light beam into reference and sample arms. The sample arm optics sequentially illuminates a location in the sample with the light beam from different angles. The detector receives light returned from the reference arm and the sample illuminated at each angle and generates signals. The processor combines the signals to generate an image, which has a transverse resolution that is higher than the transverse resolution achieved from the signal generated from a single angle.
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9.发明授权公开(公告)号：US10092178B2
公开(公告)日：2018-10-09
申请号：US14688743
申请日：2015-04-16
摘要： Systems and methods for efficiently obtaining optical coherence tomography (OCT) measurement data with reduced effects of motion are presented. One embodiment involves determining the amount of motion present during the collection of an OCT data set based on images of the eye collected at the same time as the OCT data, and recollecting select portions of the OCT data set when the amount of eye motion is determined to exceed a predetermined threshold. Another embodiment includes enabling or disabling a tracking feature based on the quality of the images available for tracking. Another embodiment includes reducing the effect of motion in the axial direction based on a comparison to a model of the eye constructed from OCT data. The method can also be used to reduce the presence of mirror image artifacts in an OCT image.
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公开(公告)号：US09456746B2
公开(公告)日：2016-10-04
申请号：US14207229
申请日：2014-03-12
发明人： Daniel Bublitz , Matthew J. Everett , Csaba Farkas , Michael Kempe , Yue Qiu , Tobias Schmitt-Manderbach
CPC分类号： A61B3/14 , A61B3/1025 , A61B3/12 , G02B21/0028 , G02B21/0032
摘要： Systems and methods for Broad Line Fundus Imaging (BLFI), an imaging approach that is a hybrid between confocal and widefield imaging systems, are presented. These systems and methods are focused on improving the quality and signal of broad line fundus images or imaging methods to create high contrast and high resolution fundus images. Embodiments related to improved pupil splitting, artifact removal, reflex minimization, adaptable field of view, instrument alignment and illumination details are considered.
摘要翻译： 介绍了广泛基线成像（BLFI）的系统和方法，这是一种成像方法，是共聚焦和广角成像系统之间的混合。 这些系统和方法专注于提高广泛眼底图像或成像方法的质量和信号，以创建高对比度和高分辨率眼底图像。 考虑与改进的瞳孔分裂，伪像去除，反射最小化，适应性视野，仪器对准和照明细节相关的实施例。
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