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公开(公告)号：US20200062869A1
公开(公告)日：2020-02-27
申请号：US16552774
申请日：2019-08-27
发明人： Stefanie A. Sydlik , Anne M. Arnold , Brian D. Holt , Cato T. Laurencin , Leila Daneshmandi , Stephen Schmidt
摘要： A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.
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公开(公告)号：US11479617B2
公开(公告)日：2022-10-25
申请号：US16552774
申请日：2019-08-27
发明人： Stefanie A. Sydlik , Anne M. Arnold , Brian D. Holt , Cato T. Laurencin , Leila Daneshmandi , Stephen Schmidt
摘要： A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.
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公开(公告)号：US20200069838A1
公开(公告)日：2020-03-05
申请号：US16610814
申请日：2018-05-03
摘要： A method for functionalizing graphene oxide includes reacting graphene oxide with a phosphite compound and a metal salt in the presence of a Lewis acid to produce phosphate functionalized graphene oxide including ions of the metal. An apparatus includes a bone scaffold construct formed of phosphate functionalized graphene oxide including metal ions. A bone scaffold construct includes a graphene oxide material formed in the shape of the bone scaffold construct, the graphene oxide material including graphene oxide, phosphate moieties covalently bound to the graphene oxide, and metal counter ions chemically associated with the phosphate moieties. A method for treating a bone defect includes administering a therapeutically effective amount of phosphate functionalized graphene oxide including metal ions.
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公开(公告)号：US20230226519A1
公开(公告)日：2023-07-20
申请号：US18007853
申请日：2021-06-04
IPC分类号： B01J20/22 , C02F1/28 , C02F1/68 , C01B32/194 , C01B32/198 , B01J20/20 , B01J20/28 , B01J20/32
CPC分类号： B01J20/22 , C02F1/288 , C02F1/683 , C01B32/194 , C01B32/198 , B01J20/205 , B01J20/28009 , B01J20/28042 , B01J20/28033 , B01J20/3204 , B01J20/3219 , B01J20/3265 , C02F1/283 , C02F1/285 , C02F2101/10
摘要： Described herein is a functional graphene composition comprising a graphene scaffold and one or more metal chelating functional groups covalently bonded to the graphene scaffold and a porous substrate that includes the functional graphene composition. Also provided is a method of removing dissolved metals from an aqueous liquid, such as, acid mine drainage.
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公开(公告)号：US12018202B2
公开(公告)日：2024-06-25
申请号：US16825001
申请日：2020-03-20
IPC分类号： C08K3/12 , C09J5/00 , C09J167/04 , C09K3/12
CPC分类号： C09K3/12 , C09J5/00 , C09J167/04
摘要： The present invention provides certain chemical compounds or materials having adhesive properties or functionality that act as adhesives or sealants in a variety of applications. In particular, the invention, including its various embodiments, relates to certain functional graphenic materials having an attached adhesive moiety that provides adhesive properties or functionality to the resulting compound and that can be used as an adhesive or sealant in a variety of applications, such as in-situ repair of a leak or defect in a tube carrying a fluid, such as a condenser tube in a power plant.
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公开(公告)号：US20200299557A1
公开(公告)日：2020-09-24
申请号：US16825001
申请日：2020-03-20
IPC分类号： C09K3/12 , C09J167/04 , C09J5/00
摘要： The present invention provides certain chemical compounds or materials having adhesive properties or functionality that act as adhesives or sealants in a variety of applications. In particular, the invention, including its various embodiments, relates to certain functional graphenic materials having an attached adhesive moiety that provides adhesive properties or functionality to the resulting compound and that can be used as an adhesive or sealant in a variety of applications, such as in-situ repair of a leak or defect in a tube carrying a fluid, such as a condenser tube in a power plant.
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