摘要:
The invention concerns an endovascular implant for the application of an active substance into the media 22 of a blood vessel and two processes for the production thereof. A base body 42 of the implant has at least in portion-wise manner at a surface 40 which is towards the blood vessel, a plurality of microdevices 10 for injection of the active substance. Each microdevice 10 includes on the one hand at least one microcannula 38 which is raised out of the surface 40 of the implant to such an extent that, when the implant bears against a wall 12 of the blood vessel in surface contact, the microcannula penetrates into the media 22 of the blood vessel, and on the other hand at least one active substance deposit 36 which is in communication with at least one microcannula 38.
摘要:
The invention concerns an endovascular implant comprising a biodegradable material and having a tubular main body which is open at the ends and which is dilatable from an unexpanded condition into an expanded condition. The implant is so designed that when the implant in the expanded condition is subjected to a radially acting compression pressure in the range of between 5 and 30 kPa (0.05-0.3 bar) a cross-sectional area of the implant is reduced to 70% or less of the original cross-sectional area, or an internal volume of the implant is reduced to 70% or less of the original internal volume.
摘要:
An endoprosthesis includes a carrier structure which contains a metallic material. The metallic material contains a magnesium alloy of the following composition: magnesium: >90%, yttrium: 3.7%-5.5%, rare earths: 1.5%-4.4% and balance:
摘要:
The invention concerns an endovascular implant comprising a biodegradable material and having a tubular main body which is open at the ends and which is dilatable from an unexpanded condition into an expanded condition. The implant is so designed that when the implant in the expanded condition is subjected to a radially acting compression pressure in the range of between 5 and 30 kPa (0.05-0.3 bar) a cross-sectional area of the implant is reduced to 70% or less of the original cross-sectional area, or an internal volume of the implant is reduced to 70% or less of the original internal volume.
摘要:
The invention relates to a medical implant made of a metallic material. After fulfilling its temporary support function, the implant is degraded by corrosion at a predetermined rate. Negative long-term effects are thus avoided.
摘要:
The invention relates to a medical implant made of a metallic material. After fulfilling its temporary support function, the implant is degraded by corrosion at a predetermined rate. Negative long-term effects are thus avoided.
摘要:
A method of treating a patient includes the medical use of one or more of the elements from the group yttrium, neodymium and zirconium, pharmaceutical formulations which contain said elements and implants which are at least region-wise made up of such formulations. It has been found inter alia that a formulation containing one or more of the elements has an action of inhibiting the proliferation of human smooth muscle cells.
摘要:
A method of treating a patient includes the medical use of one or more of the elements from the group yttrium, neodymium and zirconium, pharmaceutical formulations which contain said elements and implants which are at least region-wise made up of such formulations. It has been found inter alia that a formulation containing one or more of the elements has an action of inhibiting the proliferation of human smooth muscle cells.
摘要:
A method of treating a patient includes the medical use of one or more of the elements from the group yttrium, neodymium and zirconium, pharmaceutical formulations which contain said elements and implants which are at least region-wise made up of such formulations. It has been found inter alia that a formulation containing one or more of the elements has an action of inhibiting the proliferation of human smooth muscle cells.
摘要:
The invention concerns inter alia an implant for vessel ligature, the implant which comprises an alloy, wherein the alloy is at least partially biodegradable, and wherein the alloy comprises: greater than 87% magnesium; from about 3% to about 6% yttrium; from about 1% to about 5% lanthanide; and a balance of about 0.0% to about 2%.