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公开(公告)号：US20100297228A1
公开(公告)日：2010-11-25
申请号：US12260911
申请日：2008-10-29
申请人： Cedric Loiret-Bernal , Nabil Amro , Sandeep Disawal , Bjoern Rosner , John E. Bussan , Bo He
发明人： Cedric Loiret-Bernal , Nabil Amro , Sandeep Disawal , Bjoern Rosner , John E. Bussan , Bo He
CPC分类号： B42D25/425 , A61K9/284 , B41M3/14 , B42D25/29 , B42D25/305 , B42D2035/16 , B44B5/0052 , G06K1/12
摘要： To improve anticounterfeiting protection, a method for imprinting pharmaceutical unit compositions comprising: providing a pharmaceutical unit composition, partially coating the exterior of the composition with a coating, stamping the coating with a stamp comprising a plurality of identification features, wherein identification features from the stamp are at least partially transposed in the coating and form a barcode, wherein the plurality of identification features comprise at least one lateral dimension of about 1,000 nm or less. Other objects can be coated and stamped including currency and luxury goods.
摘要翻译： 为了改善防伪保护，一种用于印记药物单位组合物的方法，包括：提供药物单元组合物，用涂层部分地涂覆组合物的外部，用包含多个识别特征的印模冲压涂层，其中印模的识别特征 至少部分地转置在涂层中并形成条形码，其中多个识别特征包括至少一个约1000nm或更小的横向尺寸。 其他物品可以涂上和盖章，包括货币和奢侈品。
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2.发明申请Apparatus and methods for preparing identification features including pharmaceutical applications 审中-公开用于制备识别特征的装置和方法，包括药物应用公开(公告)号：US20100294147A1
公开(公告)日：2010-11-25
申请号：US11305327
申请日：2005-12-19
申请人： Cedric Loiret-Bernal , Bjoern Rosner , Sylvain Cruchon-Dupeyrat , John E. Bussan , Michael Nelson
发明人： Cedric Loiret-Bernal , Bjoern Rosner , Sylvain Cruchon-Dupeyrat , John E. Bussan , Michael Nelson
IPC分类号： B41F17/36
CPC分类号： B41F19/068 , B41F17/36
摘要： Semi-automated or automated manufacturing of micro- or nanostructured identification features on objects and compositions, and especially pharmaceutical compositions. In particular, a motorized stamping apparatus capable of precise hot embossing with or without closed-loop control of the loading; a modular stamp head for a high-throughput parallel stamping apparatus that comprise an array of compact, error-tolerant, individually temperature-controllable stamping elements; inexpensive stamp holders for said elements, as well as associated methods. The inventive features do not reside in the method of making the stamps.
摘要翻译： 在物体和组合物上，特别是药物组合物的半自动或自动化制造微结构或纳米结构的识别特征。 特别是一种电动冲压装置，能够精确地加热或不加负荷闭环控制的热压花; 用于高通量并行冲压装置的模块化压头，其包括紧凑的，容错的，单独的温度可控的冲压元件阵列; 用于所述元件的廉价邮票持有者以及相关方法。 本发明的特征不在于制作邮票的方法。
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3.发明申请APPARATUS AND METHODS FOR PREPARING IDENTIFICATION FEATURES INCLUDING PHARMACEUTICAL APPLICATIONS 审中-公开用于准备鉴定特征的装置和方法，包括药物应用公开(公告)号：US20120272845A1
公开(公告)日：2012-11-01
申请号：US13539259
申请日：2012-06-29
申请人： Cedric Loiret-Bernal , Bjoern Rosner , Sylvain Cruchon-Dupeyrat , John E. Bussan , Michael Nelson
发明人： Cedric Loiret-Bernal , Bjoern Rosner , Sylvain Cruchon-Dupeyrat , John E. Bussan , Michael Nelson
IPC分类号： B44B5/00
CPC分类号： B41F19/068 , B41F17/36
摘要： Semi-automated or automated manufacturing of micro- or nanostructured identification features on objects and compositions, and especially pharmaceutical compositions. In particular, a motorized stamping apparatus capable of precise hot embossing with or without closed-loop control of the loading; a modular stamp head for a high-throughput parallel stamping apparatus that comprise an array of compact, error-tolerant, individually temperature-controllable stamping elements; inexpensive stamp holders for said elements, as well as associated methods. The inventive features do not reside in the method of making the stamps.
摘要翻译： 在物体和组合物上，特别是药物组合物的半自动或自动化制造微结构或纳米结构的识别特征。 特别是一种电动冲压装置，能够精确地加热或不加负荷闭环控制的热压花; 用于高通量并行冲压装置的模块化压头，其包括紧凑的，容错的，单独的温度可控的冲压元件阵列; 用于所述元件的廉价邮票持有者以及相关方法。 本发明的特征不在于制作邮票的方法。
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4.发明授权Stamps with micrometer-and nanometer-scale features and methods of fabrication thereof 有权具有微米和纳米尺度特征的印模及其制造方法公开(公告)号：US08387529B2
公开(公告)日：2013-03-05
申请号：US13286954
申请日：2011-11-01
申请人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
发明人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
IPC分类号： B41C1/00
摘要： Stamps and methods of making stamps for applications in anti-counterfeiting and authentication. The stamps are relatively small in size and feature nanoscale and microscale identification regions and features. High throughput manufacturing and high resolution methods are used to make the stamps including electron beam lithography and optical lithography. Anti-fouling coatings can be applied.
摘要翻译： 邮票和制作邮票的方法，用于防伪和认证。 邮票的尺寸相对较小，具有纳米尺度和微尺度识别区域和特征。 使用高通量制造和高分辨率方法来制作邮票，包括电子束光刻和光刻。 可以应用防污涂料。
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公开(公告)号：US20100294844A1
公开(公告)日：2010-11-25
申请号：US11109877
申请日：2005-04-20
申请人： Cedric Loiret-Bernal , Linette Demers , Bjoern Rosner , Michael Nelson , Ray Eby , Joseph S. Fragala , Raymond Roger Shile , Hua Zhang , John Edward Bussan , Sylvain Cruchon-Dupeyrat
发明人： Cedric Loiret-Bernal , Linette Demers , Bjoern Rosner , Michael Nelson , Ray Eby , Joseph S. Fragala , Raymond Roger Shile , Hua Zhang , John Edward Bussan , Sylvain Cruchon-Dupeyrat
CPC分类号： B30B15/065 , B30B15/34 , G06K19/06028
摘要： Methods for providing pharmaceutical compositions and objects with identification regions and identification features which are difficult to detect. Microlithography, nanolithography, and stamping methods are used. The identification features can be positive protrusions or negative indentations with respect to the surface. The identification regions can comprise bar codes and holograms. DPN printing or other lithographies such as electron beam lithography, optical lithography, or nanoimprint lithography can be used to prepare stamps, which are then used to prepare the identification features. Redundant patterns can be formed. The invention is useful for counterfeit prevention. An apparatus for stamping the identification features is also described.
摘要翻译： 用于提供药物组合物和物体具有难以检测的识别区域和识别特征的方法。 使用微光刻，纳米光刻和冲压方法。 识别特征可以是相对于表面的正突起或负凹痕。 识别区域可以包括条形码和全息图。 可以使用DPN印刷或诸如电子束光刻，光刻或纳米压印光刻的其它平版印刷术来制备标记，然后将其用于制备识别特征。 可以形成冗余图案。 本发明可用于防伪。 还描述了用于冲压识别特征的装置。
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6.发明申请Stamps with micrometer-and nanometer-scale features and methods of fabrication thereof 有权具有微米和纳米尺度特征的印模及其制造方法公开(公告)号：US20100294146A1
公开(公告)日：2010-11-25
申请号：US11305326
申请日：2005-12-19
申请人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
发明人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
IPC分类号： B44B5/02
摘要： Stamps and methods of making stamps for applications in anti-counterfeiting and authentication. The stamps are relatively small in size and feature nanoscale and microscale identification regions and features. High throughput manufacturing and high resolution methods are used to make the stamps including electron beam lithography and optical lithography. Anti-fouling coatings can be applied.
摘要翻译： 邮票和制作邮票的方法，用于防伪和认证。 邮票的尺寸相对较小，具有纳米尺度和微尺度识别区域和特征。 使用高通量制造和高分辨率方法来制作邮票，包括电子束光刻和光刻。 可以应用防污涂料。
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公开(公告)号：US08235302B2
公开(公告)日：2012-08-07
申请号：US11109877
申请日：2005-04-20
申请人： Cedric Loiret-Bernal , Linette Demers , Bjoern Rosner , Michael Nelson , Ray Eby , Joseph S. Fragala , Raymond Roger Shile , Hua Zhang , John Edward Bussan , Sylvain Cruchon-Dupeyrat
发明人： Cedric Loiret-Bernal , Linette Demers , Bjoern Rosner , Michael Nelson , Ray Eby , Joseph S. Fragala , Raymond Roger Shile , Hua Zhang , John Edward Bussan , Sylvain Cruchon-Dupeyrat
CPC分类号： B30B15/065 , B30B15/34 , G06K19/06028
摘要： Methods for providing pharmaceutical compositions and objects with identification regions and identification features which are difficult to detect. Microlithography, nanolithography, and stamping methods are used. The identification features can be positive protrusions or negative indentations with respect to the surface. The identification regions can comprise bar codes and holograms. DPN printing or other lithographies such as electron beam lithography, optical lithography, or nanoimprint lithography can be used to prepare stamps, which are then used to prepare the identification features. Redundant patterns can be formed. The invention is useful for counterfeit prevention. An apparatus for stamping the identification features is also described.
摘要翻译： 用于提供药物组合物和物体具有难以检测的识别区域和识别特征的方法。 使用微光刻，纳米光刻和冲压方法。 识别特征可以是相对于表面的正突起或负凹痕。 识别区域可以包括条形码和全息图。 可以使用DPN印刷或诸如电子束光刻，光刻或纳米压印光刻的其它平版印刷术来制备标记，然后将其用于制备识别特征。 可以形成冗余图案。 本发明可用于防伪。 还描述了用于冲压识别特征的装置。
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8.发明申请STAMPS WITH MICROMETER-AND NANOMETER-SCALE FEATURES AND METHODS OF FABRICATION THEREOF 有权具有微型和纳米尺度特征的标准及其制造方法公开(公告)号：US20120052415A1
公开(公告)日：2012-03-01
申请号：US13286954
申请日：2011-11-01
申请人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
发明人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
摘要： Stamps and methods of making stamps for applications in anti-counterfeiting and authentication. The stamps are relatively small in size and feature nanoscale and microscale identification regions and features. High throughput manufacturing and high resolution methods are used to make the stamps including electron beam lithography and optical lithography. Anti-fouling coatings can be applied.
摘要翻译： 邮票和制作邮票的方法，用于防伪和认证。 邮票的尺寸相对较小，具有纳米尺度和微尺度识别区域和特征。 使用高通量制造和高分辨率方法来制作邮票，包括电子束光刻和光刻。 可以应用防污涂料。
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9.发明申请Overt authentication features for compositions and objects and methods of fabrication and verification thereof 审中-公开用于组合物和物体的超认证特征及其制造和验证方法公开(公告)号：US20100297027A1
公开(公告)日：2010-11-25
申请号：US11305189
申请日：2005-12-19
CPC分类号： A61K9/2072
摘要： Overt anti-counterfeiting features on objects and compositions, especially pharmaceutical compositions. In a preferred embodiment, a counterfeiting-proof overt feature that presents a visually distinctive optical variable or invariable effect is manufactured on a pharmaceutical composition using a purely physical process. Further preferred are counterfeiting-proof, overt features that comprise at least one engineered array of micro- or nanostructures. Also provided are methods and apparatus for the manufacturing of said overt features on said objects and compositions, including pharmaceutical compositions, and for verifying the authenticity of said features. The inventive features do not reside in the method of making the stamp or the instrument used for stamping.
摘要翻译： 对物体和组合物，特别是药物组合物进行防伪的特征。 在优选实施例中，使用纯物理过程在药物组合物上制造呈现视觉上独特的光学变量或不变效应的防伪显性特征。 进一步优选的是防伪的，明显的特征，其包括至少一个工程化的微结构或纳米结构的阵列。 还提供了用于制造所述物体和组合物上的所述明显特征的方法和装置，包括药物组合物，以及用于验证所述特征的真实性。 本发明的特征不在于制造用于冲压的印模或仪器的方法。
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10.发明授权Stamps with micrometer- and nanometer-scale features and methods of fabrication thereof 有权具有微米级和纳米尺度特征的印模及其制造方法公开(公告)号：US08069782B2
公开(公告)日：2011-12-06
申请号：US11305326
申请日：2005-12-19
申请人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
发明人： Joseph S. Fragala , Cedric Loiret-Bernal , Hua Zhang , Raymond Roger Shile , Bjoern Rosner , Sylvain Cruchon-Dupeyrat
IPC分类号： B41F17/36
摘要： Stamps and methods of making stamps for applications in anti-counterfeiting and authentication. The stamps are relatively small in size and feature nanoscale and microscale identification regions and features. High throughput manufacturing and high resolution methods are used to make the stamps including electron beam lithography and optical lithography. Anti-fouling coatings can be applied.
摘要翻译： 邮票和制作邮票的方法，用于防伪和认证。 邮票的尺寸相对较小，具有纳米尺度和微尺度识别区域和特征。 使用高通量制造和高分辨率方法来制作邮票，包括电子束光刻和光刻。 可以应用防污涂料。
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