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公开(公告)号：US6022554A
公开(公告)日：2000-02-08
申请号：US990367
申请日：1997-12-15
申请人： Jung-Chung Lee , Shamim Pushpala , Charles E. Lee
发明人： Jung-Chung Lee , Shamim Pushpala , Charles E. Lee
CPC分类号： A61K9/0024 , A61K9/2846 , A61K9/2853 , A61K9/5026 , A61K9/5031
摘要： This invention relates to coating formulations for coating sustained-release drug implants. The coating formulations are capable of formulations are capable of forming a porous film coat over a biologically active agent to provide a release of the active agent at a constant rate over a prolonged period of time. The pore forming agent is used in the formulation of the invention in the amount effective to regulate the release of a biologically active compound at a desired rate. Preferably, the effective amount of the pore forming agent provides long term delivery of the active agent. The invention also provides an improved implant for the sustained administration of a biologically active compound suitable for subcutaneous implantation. The invention also relates to methods for making and using the formulation and the implant of the invention.
摘要翻译： 本发明涉及用于涂覆缓释药物植入物的涂层制剂。 涂层制剂能够制备能够在生物活性剂上形成多孔膜涂层，以在长时间内以恒定速率提供活性剂的释放。 成孔剂在本发明的制剂中以有效调节生物活性化合物以所需速率释放的量使用。 优选地，成孔剂的有效量提供活性剂的长期输送。 本发明还提供了用于持续施用适于皮下植入的生物活性化合物的改进植入物。 本发明还涉及制备和使用本发明的制剂和植入物的方法。
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公开(公告)号：US06889875B2
公开(公告)日：2005-05-10
申请号：US10197627
申请日：2002-07-15
申请人： Charles E. Lee , Jung-Chung Lee
发明人： Charles E. Lee , Jung-Chung Lee
CPC分类号： B05B11/00416
摘要： A dispensing device includes a hollow body coupled to a pump mechanism having a dip tube, and to a follower piston. A well provided in the piston is generally larger in diameter than the dip tube to allow fluid in the chamber to flow down into the well as the dip tube enters the well to facilitate fluid removal after a significant portion of the fluid has been removed. In some aspects, the well walls and dip tube end are substantially conical shaped with the well walls substantially parallel to the dip tube end or having a greater angle relative to the axis of the dip tube
摘要翻译： 分配装置包括联接到具有汲取管的泵机构的空心体以及随动活塞。 在活塞中设置的孔的直径通常大于浸入管的直径，以允许腔中的流体在浸入管进入井中时向下流入井中，以便在流体的大部分被去除之后促进流体移除。 在一些方面，井壁和汲取管端部基本上为圆锥形，井壁基本上平行于汲取管端部或相对于汲取管的轴线具有更大的角度
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3.发明授权Apparatus and method for determining the amount of entrapped gas in a material 失效用于确定材料中截留气体量的装置和方法
公开(公告)号：US6082174A
公开(公告)日：2000-07-04
申请号：US132630
申请日：1998-08-11
CPC分类号： G01N7/14 , G01N33/383
摘要： An entrapped gas measuring apparatus includes a reservoir housing with a reservoir which is adapted to receive a material sample and to expand according to an expansion of the material sample when a negative pressure is applied externally to the reservoir. A parameter indicating the change in volume of the reservoir during the expansion, such as the actual change of volume of the reservoir or a change in position of a moveable wall which at least in part defines the reservoir, is detected by a detector. A processor coupled to the detector is used to determine the amount of entrapped gas based upon the detected parameter. The amount of entrapped gas determined by the processor may be the percent volume of the entrapped gas in relation to the overall volume of the sample, or may be the actual volume of the entrapped gas in the sample. Based at least in-part upon the measured amount of entrapped gas within the sample, the processor is further adapted to determine at least one of: percent volume of the substrate in the sample in relation to the overall volume of the sample; actual volume of the substrate in the sample; or density of the sample or substrate within the sample. The entrapped gas measuring apparatus may be used to produce a material having a known amount of entrapped gas by: making a first material according to a first method and which has a first amount of entrapped gas; applying a negative pressure to the sample such that the sample expands from a first volume to a second volume; detecting a parameter which is indicative of the change of sample volume under the applied negative pressure; comparing the detected parameter with a predetermined range for the parameter; and, if the detected parameter is not within the predetermined range, making a second material according to a second method which has a second amount of entrapped gas that is within the predetermined range.
摘要翻译： 夹带式气体测量装置包括具有储存器的储存器壳体，该储存器适于接收材料样品并且当负压在外部施加到储存器时根据材料样品的膨胀而膨胀。 指示在膨胀期间储存器体积变化的参数，例如储存器的体积的实际变化或至少部分限定储存器的可移动壁的位置变化，由检测器检测。 耦合到检测器的处理器用于基于检测到的参数来确定捕获气体的量。 由处理器确定的夹带气体的量可以是夹带气体相对于样品的总体积的百分比体积，或可以是样品中截留的气体的实际体积。 至少部分地基于所测量的样品中捕获的气体的量，所述处理器还适于确定以下至少一个：相对于所述样品的总体积，所述样品中的所述底物的体积百分比; 样品中基材的实际体积; 或样品中的样品或底物的密度。 包埋气体测量装置可以用于通过以下方式制造具有已知量的截留气体的材料：通过以下方式制备第一种材料：第一种方法并具有第一量的截留气体; 向样品施加负压使得样品从第一体积膨胀到第二体积; 检测在施加的负压下指示样品体积变化的参数; 将检测到的参数与参数的预定范围进行比较; 并且如果检测到的参数不在预定范围内，则根据第二种方法制造第二种材料，该第二种方法具有在预定范围内的第二量的截留气体。
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公开(公告)号：US5875901A
公开(公告)日：1999-03-02
申请号：US789775
申请日：1997-01-28
申请人： Lester W. Morrow , Charles E. Lee
发明人： Lester W. Morrow , Charles E. Lee
CPC分类号： A47F5/0068 , A47F5/0807 , A47F5/0823
摘要： A product display including a base unit having a header portion and a strip portion, the strip portion having a plurality of sets of apertures along its length and at least one product hanger having a pair of ends which are removably positionable in the apertures to secure the product hanger to the strip portion, the product hanger including a support member adapted to support products to be displayed.
摘要翻译： 一种产品显示器，包括具有头部部分和条带部分的基部单元，所述条带部分沿其长度具有多组孔，以及至少一个产品悬挂器，其具有可拆卸地定位在所述孔中的一对端部， 产品挂钩到条带部分，产品衣架包括适于支撑要显示的产品的支撑构件。
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公开(公告)号：US5074051A
公开(公告)日：1991-12-24
申请号：US555869
申请日：1990-07-20
IPC分类号： G01B5/14
CPC分类号： G01B5/14
摘要： A measuring instrument for measuring the distance from a hole, drilled at the intersection of a rib and a stringer, to the adjacent flange of the rib includes two arms projecting laterally out from the side of the instrument and forward to engage the flange. The arms are geared together at their inner ends within the body of the instrument to insure that the angles of both arms relative to the longitudinal axis of the body are equal to each other so that the longitudinal axis of the instrument in use remains perpendicular to the face of the flange. A spring loaded conical hole-centering probe protruding from the bottom face of the instrument fits into and centers itself in the hole and establishes a reference from which the flange is measured. A stylus, slidably mounted in the instrument and protruding from the front end thereof, contacts the face of the flange. A linear measuring gauge measures the position of the stylus in the instrument to provide an accurate measure of the distance of the flange to the hole in a direction perpendicular to the flange.
摘要翻译： 用于测量从肋和桁条的相交处钻出的孔到肋的相邻凸缘的距离的测量仪器包括从仪器侧面横向突出的两个臂，并向前与凸缘接合。 臂在其内部端部在仪器的主体内啮合在一起，以确保两个臂相对于主体的纵向轴线的角度彼此相等，使得使用中的仪器的纵向轴线垂直于 法兰面。 从仪器底面突出的弹簧加载的圆锥孔定心探针装入并将其自身中心安装在孔中，并建立了测量法兰的参考。 可滑动地安装在仪器中并从其前端突出的触针接触凸缘的表面。 线性测量仪测量仪器中触针的位置，以便在与法兰垂直的方向上精确测量法兰与孔的距离。
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公开(公告)号：US4628496A
公开(公告)日：1986-12-09
申请号：US635300
申请日：1984-07-27
申请人： Charles E. Lee
发明人： Charles E. Lee
CPC分类号： G01S15/04 , E05F15/43 , E05F15/608 , E05F15/73 , E05F2015/433 , E05F2015/434 , E05F2015/763 , E05G5/003 , E05Y2600/46 , E05Y2900/132 , Y10T307/773
摘要： The presence of persons in a space is sensed with the aid of ultrasonic pulses which are sent out into the space when echoes of such ultrasonic pulses are received. Echoes attributable to the floor or to parts of a door in the space are timed out, and a remainder of such echoes is employed for sensing persons in the space. For example, sliding or revolving doors may be controlled and operated with the aid of such ultrasonic echoes, and limited access to secured areas may be provided thereby.
摘要翻译： 借助超声波脉冲感测在空间中存在的人，当接收到这种超声波脉冲的回波时，超声脉冲被发送到空间中。 归因于地板或空间中门的部分的回波被超时，并且其余的这种回波被用于感测该空间中的人。 例如，可以借助于这种超声波回波来控制和操作滑动门或旋转门，从而可以提供有限的进入安全区域。
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公开(公告)号：US4446335A
公开(公告)日：1984-05-01
申请号：US342253
申请日：1982-01-25
申请人： Charles E. Lee , C. Marlon Combs
发明人： Charles E. Lee , C. Marlon Combs
CPC分类号： H04M1/656
摘要： Disclosed audio signal recording methods and apparatus operate with a telephone set having a housing and a handset connected to a first modular jack in the housing via a handset cord having at an end thereof a first modular plug fitting into the first modular jack. For audio signal tapping purposes, there is provided a second modular plug fitting into the first modular jack, a second modular jack for receiving the first modular plug, and an electrical interconnection of the second modular jack with the second modular plug. The second modular plug is inserted into the first modular jack and the first modular plug into the second modular jack. Audio signals are tapped from the electrical interconnection of the second modular jack with the second modular plug and are recorded.
摘要翻译： 公开的音频信号记录方法和装置通过具有外壳的手机和手机连接到壳体中的第一模块插座，经由手机芯线，其手柄线的端部具有与第一模块化插孔相配合的第一模块插头。 为了音频信号窃听目的，提供了一个第二模块化插头装配到第一模块化插座中，第二模块插座用于接收第一模块化插头，以及第二模块插座与第二模块插头的电互连。 第二个模块化插头插入第一个模块化插座，第一个模块插头插入第二个模块插座。 音频信号从第二模块插座与第二模块插头的电气互连中抽出并被记录。
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公开(公告)号：US4382679A
公开(公告)日：1983-05-10
申请号：US193987
申请日：1980-10-06
申请人： Charles E. Lee
发明人： Charles E. Lee
CPC分类号： G01M3/226
摘要： An improved method for testing the integrity of containers and closures for same is disclosed which is simple, easy to perform, and possesses a high degree of sensitivity. The method comprises immersing a container (whose walls are substantially transparent and in which a substantially transparent liquid is stored) into a solution of a dye under conditions which will favor the passage of the dye through any leaks present in the container or closure and into the liquid. The container is then placed in the path of a laser beam emitting a wavelength which approximates the fluorescent excitation frequency of the dye. If the color of the beam transmitted through the liquid is that which is characteristic for the fluorescing dye, a leak in the system is indicated.
摘要翻译： 公开了用于测试容器和封闭件的完整性的改进方法，其简单，易于执行并且具有高度的灵敏度。 该方法包括将有利于染料通过容器或封闭物中存在的任何泄漏的条件下将容器（其壁基本上是透明的，其中储存基本上透明的液体）浸入染料溶液中并进入 液体。 然后将容器放置在发射近似染料的荧光激发频率的波长的激光束的路径中。 如果透过液体的光束的颜色是荧光染料的特征，则会显示系统中的泄漏。
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