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1.Benzofuran derivatives useful for treating hyper-proliferative disorders 失效
标题翻译: 可用于治疗高增殖性疾病的苯并呋喃衍生物公开(公告)号:US07659412B2
公开(公告)日:2010-02-09
申请号:US12201547
申请日:2008-08-29
申请人: Chengzhi Zhang , Jacques Dumas , Gaetan Ladouceur , Qian Zhao , Martin Hentemann , Sharad Verma , Qingming Zhu , Rico Lavoie , Jianmei Fan , Barton Phillips
发明人: Chengzhi Zhang , Jacques Dumas , Gaetan Ladouceur , Qian Zhao , Martin Hentemann , Sharad Verma , Qingming Zhu , Rico Lavoie , Jianmei Fan , Barton Phillips
IPC分类号: C07D307/87 , A61K31/34
CPC分类号: C07D307/83 , C07D307/80 , C07D307/81 , C07D307/82 , C07D405/04
摘要: The invention relates to novel benzofuran derivatives, processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
摘要翻译: 本发明涉及新的苯并呋喃衍生物,其制备方法及其用于制备用于治疗或预防病症,特别是过度增殖性疾病的药物的用途。
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2.BENZOFURAN DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS 失效
标题翻译: 适用于治疗高血压疾病的苯唑嘌呤衍生物公开(公告)号:US20090023783A1
公开(公告)日:2009-01-22
申请号:US12201547
申请日:2008-08-29
申请人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
发明人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
IPC分类号: A61K31/443 , C07D307/85 , C07D407/10 , A61P35/00 , A61K31/343
CPC分类号: C07D307/83 , C07D307/80 , C07D307/81 , C07D307/82 , C07D405/04
摘要: The invention relates to novel benzofuran derivatives, processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders
摘要翻译: 本发明涉及新的苯并呋喃衍生物,其制备方法及其用于制备用于治疗或预防病症,特别是过度增殖性疾病的药物的用途
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公开(公告)号:US07803956B2
公开(公告)日:2010-09-28
申请号:US12471335
申请日:2009-05-22
申请人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin F. Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
发明人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin F. Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
IPC分类号: C07D307/87 , A01N43/12 , A01N43/08
CPC分类号: C07D307/83 , C07D307/80 , C07D307/81 , C07D307/82 , C07D405/04
摘要: The invention relates to novel benzofuran derivatives, processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
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公开(公告)号:US20090292014A1
公开(公告)日:2009-11-26
申请号:US12471335
申请日:2009-05-22
申请人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin F. Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
发明人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin F. Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
IPC分类号: A61K31/343
CPC分类号: C07D307/83 , C07D307/80 , C07D307/81 , C07D307/82 , C07D405/04
摘要: The invention relates to novel benzofuran derivatives, processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders
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5.Benzofuran derivatives useful for treating hyper-proliferative disorders 失效
标题翻译: 可用于治疗高增殖性疾病的苯并呋喃衍生物公开(公告)号:US07420066B2
公开(公告)日:2008-09-02
申请号:US10566343
申请日:2004-08-06
申请人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin F. Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
发明人: Chengzhi Zhang , Jacques Dumas , Gaetan H. Ladouceur , Qian Zhao , Martin F. Hentemann , Sharad K. Verma , Qingming Zhu , Rico C. Lavoie , Jianmei Fan , Barton Phillips
IPC分类号: C07D307/87 , A61K31/34
CPC分类号: C07D307/83 , C07D307/80 , C07D307/81 , C07D307/82 , C07D405/04
摘要: The invention relates to novel heterocycles of formula (I), processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
摘要翻译: 本发明涉及式(I)的新型杂环,其制备方法及其用于制备用于治疗或预防病症,特别是过度增殖性疾病的药物的用途。
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6.Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders 失效
标题翻译: 用于治疗高增殖性疾病的取代的四氢苯并噻吩并嘧啶胺化合物公开(公告)号:US20060293322A1
公开(公告)日:2006-12-28
申请号:US10557090
申请日:2004-07-23
申请人: Chengzhi Zhang , Gaetan Ladouceur , Catherine Brennan , Brent Chandler , Julie Dizon , Karl Miranda , Dongping Fan , Qingming Zhu , Sharad Verma , Jacques Dumas
发明人: Chengzhi Zhang , Gaetan Ladouceur , Catherine Brennan , Brent Chandler , Julie Dizon , Karl Miranda , Dongping Fan , Qingming Zhu , Sharad Verma , Jacques Dumas
IPC分类号: A61K31/5377 , A61K31/519 , C07D498/02
CPC分类号: C07D495/04 , C07D498/02
摘要: The present invention relates to a compound of Formula (I) and its use in treating hyper-proliferative disorders.
摘要翻译: 本发明涉及式(I)化合物及其在治疗高增殖性疾病中的用途。
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7.Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders 有权
标题翻译: 用于治疗癌症和其他疾病的新型双环脲衍生物公开(公告)号:US20050038031A1
公开(公告)日:2005-02-17
申请号:US10788426
申请日:2004-03-01
申请人: Jacques Dumas , Stephen Boyer , Sharad Verma , Lila Adnane , Yuanwei Chen , Wendy Lee , Barton Phillips , Roger Smith , William Scott , Jennifer Burke , Jianqing Chen , Zhi Chen , Jianmei Fan , Karl Miranda , Brian Raudenbush , Aniko Redman , Jianxing Shao , Ning Su , Gan Wang , Lin Yi , Qingming Zhu
发明人: Jacques Dumas , Stephen Boyer , Sharad Verma , Lila Adnane , Yuanwei Chen , Wendy Lee , Barton Phillips , Roger Smith , William Scott , Jennifer Burke , Jianqing Chen , Zhi Chen , Jianmei Fan , Karl Miranda , Brian Raudenbush , Aniko Redman , Jianxing Shao , Ning Su , Gan Wang , Lin Yi , Qingming Zhu
IPC分类号: A61K31/335 , A61K31/416 , A61K31/4184 , A61K31/4192 , A61K31/423 , A61K31/428 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/444 , A61K31/4709 , A61K31/498 , A61K31/53 , A61K31/538 , A61K31/5415 , A61P35/00 , C07D213/68 , C07D213/79 , C07D213/84 , C07D251/02 , C07D333/66 , C07D401/12 , C07D405/12 , C07D417/12
CPC分类号: C07D213/84 , C07D401/12 , C07D405/12 , C07D417/12
摘要: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
摘要翻译: 本发明涉及新的二芳基脲,含有这些化合物的药物组合物以及这些化合物或组合物用于治疗高增殖和血管生成障碍,作为唯一试剂或与细胞毒性疗法组合的用途。
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8.Cyanopyridine derivatives useful in the treatment of cancer and other disorders 有权
标题翻译: 可用于治疗癌症和其他疾病的氰基吡啶衍生物公开(公告)号:US07557129B2
公开(公告)日:2009-07-07
申请号:US10788029
申请日:2004-02-27
申请人: William J. Scott , Jacques Dumas , Stephen Boyer , Wendy Lee , Yuanwei Chen , Barton Phillips , Sharad Verma , Jianqing Chen , Zhi Chen , Jianmei Fan , Brian Raudenbush , Aniko Redman , Lin Yi , Qingming Zhu , Lila Adnane
发明人: William J. Scott , Jacques Dumas , Stephen Boyer , Wendy Lee , Yuanwei Chen , Barton Phillips , Sharad Verma , Jianqing Chen , Zhi Chen , Jianmei Fan , Brian Raudenbush , Aniko Redman , Lin Yi , Qingming Zhu , Lila Adnane
IPC分类号: A61K31/4433 , C07D405/12
CPC分类号: C07D213/84 , C07D401/12 , C07D405/12 , C07D417/12
摘要: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
摘要翻译: 本发明涉及新的二芳基脲,含有这些化合物的药物组合物以及这些化合物或组合物用于治疗高增殖和血管生成障碍,作为唯一试剂或与细胞毒性疗法组合的用途。
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9.Bicyclic urea derivatives useful in the treatment of cancer and other disorders 有权
标题翻译: 用于治疗癌症和其他疾病的双环脲衍生物公开(公告)号:US08076488B2
公开(公告)日:2011-12-13
申请号:US10788426
申请日:2004-03-01
申请人: Jacques Dumas , Stephen Boyer , Sharad Verma , Lila Adnane , Yuanwei Chen , Wendy Lee , Barton Phillips , Roger A. Smith , William J. Scott , Jennifer Burke , Jianqing Chen , Zhi Chen , Jianmei Fan , Karl Miranda , Brian Raudenbush , Aniko Redman , Jianxing Shao , Ning Su , Gan Wang , Lin Yi , Qingming Zhu
发明人: Jacques Dumas , Stephen Boyer , Sharad Verma , Lila Adnane , Yuanwei Chen , Wendy Lee , Barton Phillips , Roger A. Smith , William J. Scott , Jennifer Burke , Jianqing Chen , Zhi Chen , Jianmei Fan , Karl Miranda , Brian Raudenbush , Aniko Redman , Jianxing Shao , Ning Su , Gan Wang , Lin Yi , Qingming Zhu
IPC分类号: C07D213/62 , C07D401/00 , C07D417/00
CPC分类号: C07D213/84 , C07D401/12 , C07D405/12 , C07D417/12
摘要: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
摘要翻译: 本发明涉及新的二芳基脲,含有这些化合物的药物组合物以及这些化合物或组合物用于治疗高增殖和血管生成障碍,作为唯一试剂或与细胞毒性疗法组合的用途。
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10.Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders 失效
标题翻译: 苯并呋喃和苯并噻吩衍生物可用于治疗高增殖性疾病公开(公告)号:US07351735B2
公开(公告)日:2008-04-01
申请号:US10501689
申请日:2003-02-21
申请人: Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Jianmei Fan , Holia Hatoum-Mokdad , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips
发明人: Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Jianmei Fan , Holia Hatoum-Mokdad , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips
IPC分类号: A61K31/343 , A61K31/381 , C07D307/80 , C07D333/56
CPC分类号: C07D307/82 , C07D307/92 , C07D307/93 , C07D333/66 , C07D333/74 , C07D333/78 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/14 , C07D407/06 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D493/04
摘要: This invention relates to novel benzofuran and benzothiophene derivatives of the general table formula and their use for the treatment of hyper-proliferative disorders
摘要翻译: 本发明涉及一般表配方的新型苯并呋喃和苯并噻吩衍生物及其用于治疗高增殖性疾病的用途
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