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公开(公告)号：US07332344B2
公开(公告)日：2008-02-19
申请号：US10086213
申请日：2002-02-28
IPC分类号： G01N21/76
CPC分类号： G01N33/54373 , C12Q1/6818 , C12Q1/6837 , G01N21/6428 , G01N2021/6432 , Y10S435/968 , Y10T436/13 , C12Q2565/101 , C12Q2563/155 , C12Q2565/519 , C12Q2563/103
摘要： A method of detecting an analyte is described in which an up-converting luminescent species that is excited by absorption of long wavelength light is provided as a donor of energy to an acceptor species that can be bound to, or generated in proximity to, the luminescent species. The analyte either alters the proximity between the luminescent species and the acceptor species or alters the absorbance or luminescence properties of the acceptor species. The luminescent energy donor is excited with long wavelength light and transfers up-converted energy to the proximate acceptor species and this transfer of energy is detected by measurement of appropriate luminescence properties of either the donor or of the acceptor or both.
摘要翻译： 描述了检测分析物的方法，其中通过吸收长波长光而激发的上转换发光物质被提供作为能量供体给受体物质，所述受体物质可以与发光物质结合或产生在发光 种类。 分析物改变发光物质和受体物质之间的接近度，或改变受体物质的吸收或发光性质。 发光能量供体被长波长的光激发，并将上转换的能量转移到邻近的受体物质，并且通过测量供体或受体或两者的合适的发光性质来检测能量的转移。
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公开(公告)号：US20110017247A1
公开(公告)日：2011-01-27
申请号：US12509225
申请日：2009-07-24
IPC分类号： B08B6/00
CPC分类号： B08B7/0035 , H01J37/02 , H01J37/26 , H01J2237/022 , H01J2237/16 , H01J2237/20
摘要： An apparatus for cleaning the specimen and interior specimen chamber of Transmission Electron Microscopes, and similar electron- or charged-particle-beam instruments consisting of a plasma cleaning device mounted on a hollow rod that replaces the stage through the air lock of the instrument by being the same shape and size as the stage support rod. The plasma cleaning device is a small hollow cathode that is excited by RF power. Air or other oxygen containing mixtures is admitted to the plasma through the hollow rod at a pressure below 1 Torr. The plasma creates oxygen radicals from the oxygen containing gas. The oxygen radicals oxidize the hydrocarbons contamination and convert them to easily pumped gases. The apparatus can be attached to the electron microscope whenever cleaning is needed, and then is easily removed to return the instrument to its analytical function.
摘要翻译： 一种用于清洁透射电子显微镜的样品和内部样品室的装置，以及类似的电子或带电粒子束仪器，其由安装在空心棒上的等离子体清洁装置组成，其通过仪器的气锁代替台架 与舞台支撑杆相同的形状和尺寸。 等离子体清洁装置是由RF功率激发的小型空心阴极。 空气或其它含氧混合物通过空心棒在低于1乇的压力下进入等离子体。 等离子体从含氧气体中产生氧自由基。 氧自由基氧化碳氢化合物污染并将其转化为容易抽取的气体。 每当需要清洁时，该装置可以连接到电子显微镜，然后容易地移除，以使仪器返回其分析功能。
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公开(公告)号：US08349125B2
公开(公告)日：2013-01-08
申请号：US12509225
申请日：2009-07-24
IPC分类号： C23F1/00 , H01L21/306
CPC分类号： B08B7/0035 , H01J37/02 , H01J37/26 , H01J2237/022 , H01J2237/16 , H01J2237/20
摘要： An apparatus for cleaning the specimen and interior specimen chamber of Transmission Electron Microscopes, and similar electron- or charged-particle-beam instruments consisting of a plasma cleaning device mounted on a hollow rod that replaces the stage through the air lock of the instrument by being the same shape and size as the stage support rod. The plasma cleaning device is a small hollow cathode that is excited by RF power. Air or other oxygen containing mixtures is admitted to the plasma through the hollow rod at a pressure below 1 Torr. The plasma creates oxygen radicals from the oxygen containing gas. The oxygen radicals oxidize the hydrocarbons contamination and convert them to easily pumped gases. The apparatus can be attached to the electron microscope whenever cleaning is needed, and then is easily removed to return the instrument to its analytical function.
摘要翻译： 一种用于清洁透射电子显微镜的样品和内部样品室的装置，以及类似的电子或带电粒子束仪器，其由安装在空心棒上的等离子体清洁装置组成，其通过仪器的气锁代替台架 与舞台支撑杆相同的形状和尺寸。 等离子体清洁装置是由RF功率激发的小型空心阴极。 空气或其它含氧混合物通过空心棒在低于1乇的压力下进入等离子体。 等离子体从含氧气体产生氧自由基。 氧自由基氧化碳氢化合物污染并将其转化为容易抽取的气体。 每当需要清洁时，该装置可以连接到电子显微镜，然后容易地移除，以使仪器返回其分析功能。
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公开(公告)号：US5459323A
公开(公告)日：1995-10-17
申请号：US927504
申请日：1992-09-11
CPC分类号： G01N21/6408 , G01J2001/442 , G01J2001/448 , G01J2001/4493
摘要： Apparatus for producing decay time weighted information (e.g. a decay time weighted image) of a luminescent sample, comprises an excitation light source arranged to illuminate the sample, means for modulating or pulsing the intensity of the excitation light in a predetermined cyclical manner, detector means for detecting photons emitted by the sample as a result of luminescence, means for storing data representative of detected photons, the stored data being weighted as a function of phase difference between detection of photons and the cyclically varying modulation, and means for producing decay time weighted information from the stored data.
摘要翻译： PCT No.PCT / GB91 / 00046 Sec。 371日期：1992年9月11日 102（e）1992年9月11日PCT PCT 1991年1月14日PCT公布。 公开号WO91 / 10897 日期：1991年7月25日。用于制造发光样品的衰减时间加权信息（例如衰减时间加权图像）的装置包括布置成照射样品的激发光源，用于调制或脉冲激发光强度的装置 预定的周期性方式，用于检测作为发光的结果由样品发射的光子的检测器装置，用于存储表示检测到的光子的数据的装置，所存储的数据被加权为光子的检测与循环变化的调制之间的相位差的函数， 以及用于从存储的数据产生衰减时间加权信息的装置。
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