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公开(公告)号：US5459323A
公开(公告)日：1995-10-17
申请号：US927504
申请日：1992-09-11
CPC分类号： G01N21/6408 , G01J2001/442 , G01J2001/448 , G01J2001/4493
摘要： Apparatus for producing decay time weighted information (e.g. a decay time weighted image) of a luminescent sample, comprises an excitation light source arranged to illuminate the sample, means for modulating or pulsing the intensity of the excitation light in a predetermined cyclical manner, detector means for detecting photons emitted by the sample as a result of luminescence, means for storing data representative of detected photons, the stored data being weighted as a function of phase difference between detection of photons and the cyclically varying modulation, and means for producing decay time weighted information from the stored data.
摘要翻译： PCT No.PCT / GB91 / 00046 Sec。 371日期：1992年9月11日 102（e）1992年9月11日PCT PCT 1991年1月14日PCT公布。 公开号WO91 / 10897 日期：1991年7月25日。用于制造发光样品的衰减时间加权信息（例如衰减时间加权图像）的装置包括布置成照射样品的激发光源，用于调制或脉冲激发光强度的装置 预定的周期性方式，用于检测作为发光的结果由样品发射的光子的检测器装置，用于存储表示检测到的光子的数据的装置，所存储的数据被加权为光子的检测与循环变化的调制之间的相位差的函数， 以及用于从存储的数据产生衰减时间加权信息的装置。
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2.发明授权
公开(公告)号：US5153424A
公开(公告)日：1992-10-06
申请号：US651476
申请日：1991-02-06
申请人： Mark E. Gramer
发明人： Mark E. Gramer
CPC分类号： H01J29/98 , G01J1/44 , H01J43/30 , G01J2001/4406 , G01J2001/4493 , H01J2231/50015 , H01J2231/50063
摘要： A flux monitor high light intensity cut-off circuit for a night vision device which includes a photo detector and an integrator. Incident light striking the photo detector causes its resistance to change, resulting in a voltage change at the photo detector. As long as the photo detector voltage is below a first threshold voltage level, the integrator is inoperative. When the voltage at the photo detector exceeds the first threshold voltage level, this voltage is then applied to the input of the integrator. The integrator then produces an output voltage proportional to the integral of the input current. Once the output voltage of the integrator reaches a second threshold voltage, power to an image intensifier assembly within the night vision device is interrupted.
摘要翻译： 用于夜视装置的通量监视器高光强度截止电路，其包括光电检测器和积分器。 入射到光电检测器的入射光引起其电阻变化，导致光电检测器的电压变化。 只要光电检测器电压低于第一阈值电压电平，积分器就不起作用。 当光检测器的电压超过第一阈值电压时，该电压然后被施加到积分器的输入。 然后，积分器产生与输入电流的积分成比例的输出电压。 一旦积分器的输出电压达到第二阈值电压，则夜视设备内的图像增强器组件的功率被中断。
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公开(公告)号：USRE35868E
公开(公告)日：1998-08-11
申请号：US565580
申请日：1995-11-30
申请人： Tokihiro Kosaka
发明人： Tokihiro Kosaka
CPC分类号： G01N15/1427 , G01N15/1459 , G01N15/1463 , G01J2001/4493 , G01N2015/1465 , G01N2015/1477
摘要： An apparatus for imaging and analyzing particle components in a sample liquid flow containing particle components such as blood and urine, or fine particles of organic high polymer in suspension or the like. A conventional particle imaging flow cytometer is combined with a light source such as a lamp with small coherence, and an image intensifier with gate function of high response, so that a clear particle image without a deflection or interference fringe is obtained. Thus, in the apparatus having the still imaging function, by using the image intensifier with a high speed gate function, even with a light source of a long luminous time such as a lamp, a clear still image of a particle flowing at high speed is obtained.
摘要翻译： 用于成像和分析含有血液和尿液等微粒成分的样品液体流中的微粒成分或悬浮液等中的有机高聚物微粒的装置。 常规的颗粒成像流式细胞仪与诸如具有小相干性的灯的光源和具有高响应的门功能的图像增强器组合，从而获得没有偏转或干涉条纹的清晰的颗粒图像。 因此，在具有静止成像功能的装置中，通过使用具有高速门功能的图像增强器，即使使用诸如灯的长发光时间的光源，高速流动的颗粒的清晰静止图像是 获得。
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公开(公告)号：US5149972A
公开(公告)日：1992-09-22
申请号：US466889
申请日：1990-01-18
申请人： Frederic Fay , Fernando Dellaville
发明人： Frederic Fay , Fernando Dellaville
CPC分类号： G01N21/6458 , G02B21/0096 , G02B21/16 , H04N5/235 , H04N5/30 , G01J2001/4493 , G01N2021/1772 , G01N2021/6419 , G01N21/6456 , G01N2201/0696
摘要： An imaging apparatus which includes: a fluorescent imaging microscope; a uv radiation source capable of producing a plurality of uv excitation wavelengths; a filter device to select a first and a second excitation wavelength from the plurality of uv excitation wavelengths; a sample chamber to hold a sample for illumination by the radiation of the first and second wavelengths; a photometer to measure the intensity of the excitation wavelength being selected by the filter device and to generate an intensity signal representative of the measured intensity; and a processor in communication with the photometer to record the intensity signal produced by the photometer.
摘要翻译： 一种成像装置，包括：荧光成像显微镜; 能够产生多个紫外激发波长的紫外辐射源; 滤波器装置，用于从所述多个uv激发波长中选择第一和第二激发波长; 样品室，用于通过第一和第二波长的辐射保持用于照明的样品; 光度计，用于测量由过滤装置选择的激发波长的强度，并产生表示测量强度的强度信号; 以及与光度计通信的处理器，以记录由光度计产生的强度信号。
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5.发明授权
公开(公告)号：US5471299A
公开(公告)日：1995-11-28
申请号：US256983
申请日：1994-07-29
申请人： Paul H. Kaye , Edwin Hirst
发明人： Paul H. Kaye , Edwin Hirst
CPC分类号： G01N15/1436 , G01J2001/448 , G01J2001/4493 , G01N15/1427 , G01N15/1459 , G01N2015/0046 , G01N2015/1402 , G01N2015/144 , G01N2021/4714
摘要： An apparatus for the analysis of individual particle characteristics from an aerosol or other suspension of particles, of the type having a scattering chamber (15) with an ellipsoidal reflector (17) and an orifice leading to a rear chamber (20), and a monochromatic light source (10) adapted to transmit a collimated beam of light (11) along the main axis of the reflector (17) to impinge on a stream of the particles reflector (17), has an optical system (17, 32, 33, 34) arranged to collect light back-scattered from a particle, through a solid angle of at least 3.pi., pass the light to a a ccd video recorder (36) having a two dimensional array of a multitude of sensors.The recorder (36) is associated with a data processor (37) and with an imaging screen (35) positioned such that rays of light scattered from the particle and imaged thereon by the optical system (17, 32, 33, 34) are monotonically ordered with respect to the angle of scattering of the rays from the particle.
摘要翻译： PCT No.PCT / GB93 / 00337 Sec。 371日期1994年7月29日第 102（e）日期1994年7月29日PCT提交1993年2月18日PCT公布。 公开号WO93 / 17322 日本1993年9月2日。一种用于从气溶胶或其它颗粒悬浮液分析颗粒特性的装置，其具有具有椭圆反射器（17）的散射室（15）和通向后室的孔 （20），并且适于沿着所述反射器（17）的主轴传输准直光束（11）以撞击所述粒子反射器（17）的流的单色光源（10）具有光学系统 （17,32,33,34），被布置成收集从颗粒反射散射的光，通过至少3ppi的立体角，将光通过具有二维阵列的二维阵列的一个ccd录像机（36） 传感器。 记录器（36）与数据处理器（37）相关联，并且成像屏幕（35）定位成使得由光学系统（17,32,33,34）从颗粒散射并在其上成像的光线单调地 相对于来自颗粒的射线的散射角度排序。
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公开(公告)号：US5272354A
公开(公告)日：1993-12-21
申请号：US933737
申请日：1992-08-24
申请人： Tokihiro Kosaka
发明人： Tokihiro Kosaka
CPC分类号： G01N15/1427 , G01N15/1459 , G01N15/1463 , G01J2001/4493 , G01N2015/1465 , G01N2015/1477
摘要： An apparatus for imaging and analyzing particle components in a sample liquid flow containing particle components such as blood and urine, or fine particles of organic high polymer in suspension or the like. A conventional particle imaging flow cytometer is combined with a light source such as a lamp with small coherence, and an image intensifier with gate function of high response, so that a clear particle image without a deflection or interference fringe is obtained. Thus, in the apparatus having the still imaging function, by using the image intensifier with a high speed gate function, even with a light source of a long luminous time such as a lamp, a clear still image of a particle flowing at high speed is obtained.
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7.发明授权
公开(公告)号：US4573195A
公开(公告)日：1986-02-25
申请号：US528007
申请日：1983-08-31
申请人： Henri G. de France
发明人： Henri G. de France
CPC分类号： G01N21/6456 , G01J2001/4493 , G01N15/1468 , G01N2021/6471 , G01N21/6458 , G01N2201/102 , Y10S436/80 , Y10S436/805
摘要： A system for the automatic observation and quantification of phenomena capable of being detected by fluorescence and appearing in a localized zone (8), the system comprising a source of radiation (2), optionally associated with an excitation filter (5) to send on the localized zone (8) an excitation radiation capable of producing the fluorescence, optical observation means (7) of the localized zone (8) and at least one filter (12) intended to block the excitation radiation and arranged in the path of the luminous radiation of fluorescence emanating from the localized zone (8). In accordance with the invention, the localized zone (8) is observed by a picture-taking tube (17) and through colored filters or windows on a disc (18) intercepting beam 11. The sucessive colored images are memorized and then read simultaneously.
摘要翻译： 一种用于自动观察和量化能够通过荧光检测并出现在局部区域（8）中的现象的系统，所述系统包括辐射源（2），可选地与激发滤光器（5）相关联以在 局部区域（8）能够产生荧光的激发辐射，局部区域（8）的光学观察装置（7）和用于阻挡激发辐射并且布置在发光辐射路径中的至少一个滤光器（12） 的从局部区域发出的荧光（8）。 根据本发明，通过摄影管（17）和截取光束11的盘（18）上的彩色滤光片或窗口来观察局部区域（8）。存储有色彩的图像然后同时读取。
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公开(公告)号：US5281826A
公开(公告)日：1994-01-25
申请号：US813112
申请日：1991-12-23
CPC分类号： G01N21/6456 , G01J2001/4493 , G01N2021/177 , G01N2201/0221
摘要： Disclosed is a real-time fluorescence imaging system for detecting on-site the presence and boundaries of spills of insulating liquids for transformers and capacitors and other fluorescing materials providing a two- dimensional image of the spill having excitement means positionable near a spill for exciting fluorescence emissions from the spill materials, image intensification means for intensifying the fluorescent emissions, first detection means positionable to detect intensified fluorescent emissions from the insulating liquids and generating a detection signal, and display means for receiving the detection signal and generating a real-time video image of the presence and boundaries of the spill. The present invention also includes pulse means for causing the excitement means to periodically excite fluorescent emissions from the insulating liquids and control means for controlling the intensification means to intensify only during periods of fluorescent excitation.
摘要翻译： 公开了一种实时荧光成像系统，用于现场检测用于变压器和电容器以及其它荧光材料的绝缘液体泄漏的存在和边界，从而提供溢出物的二维图像，其具有靠近溢出物定位的激发装置用于激发荧光 来自泄漏材料的排放物，用于增强荧光发射的图像增强装置，能够检测来自绝缘液体的增强的荧光发射并产生检测信号的第一检测装置，以及用于接收检测信号并产生实时视频图像的显示装置 溢出物的存在和边界。 本发明还包括用于使兴奋装置周期性地激励来自绝缘液体的荧光发射的脉冲装置和用于仅在荧光激发期间控制增强装置强化的控制装置。
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公开(公告)号：US5053626A
公开(公告)日：1991-10-01
申请号：US414755
申请日：1989-09-29
申请人： Douglas L. Tillotson
发明人： Douglas L. Tillotson
CPC分类号： G01N21/6458 , G01J2001/4493 , G01N2021/6419 , G01N2021/6471 , G01N21/6456
摘要： A spectrofluorometry apparatus utilizes dual wavelengths. The dual wavelengths are produced using different wavelength filters and a rotating reflective disk that direct the light to each of the respective filters. The reflective disk contains a notch that allows light to pass through it and two reflective surfaces that reflect light. As the disk rotates, the light is appropriately distributed to the respective filters. The rotation of the reflective disk is synchronized to a video camera that is used to image fluorescence. The camera is designed so that each of the wavelengths are giving alternating video frames.
摘要翻译： 分光荧光测量装置利用双波长。 双波长是使用不同的波长滤波器和将光引导到各个滤波器的旋转反射盘产生的。 反射盘包含允许光通过的凹口和反射光的两个反射表面。 当盘旋转时，光适当地分配到各个滤光器。 反射盘的旋转与用于成像荧光的摄像机同步。 相机被设计成使得每个波长都提供交替的视频帧。
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公开(公告)号：US4773097A
公开(公告)日：1988-09-20
申请号：US40770
申请日：1987-04-20
申请人： Takuji Suzaki , Koji Yamamoto , Satoko Nakajima
发明人： Takuji Suzaki , Koji Yamamoto , Satoko Nakajima
IPC分类号： A61B5/08 , A61B5/00 , A61B5/145 , A61B10/00 , G01B11/00 , G01J1/44 , G01N21/64 , H04N7/18 , G06K9/00
CPC分类号： G01N21/6456 , A61B5/0059 , G01J2001/4493 , G01N2021/6493
摘要： An image analyzing apparatus comprising a source of light for radiating a target object of interest, a measuring light of a first predetermined wavelength and at least one detecting light of a second predetermined wavelength different from the first predetermined wavelength, which detecting light is utilized to detect an optically disturbing component, a camera unit for forming a measured image of the target object radiated by the measuring light and a detected image of the target object radiated by the detecting light, and capable of generating output signals representative of the respective measured and detected images, a processor for deriving an interference equation descriptive of an interference given by the optically disturbing component, on the basis of the measured and detected images outputed from the camera unit, a computer for eliminating the optically disturbing component from the measured image on the basis of the interference equation, and a display device for providing a visual representation of an image output from the computer.
摘要翻译： 一种图像分析装置，包括用于照射目标物体的光源，第一预定波长的测量光和与第一预定波长不同的第二预定波长的至少一个检测光，该检测光用于检测 光学干扰部件，用于形成由测量光辐射的目标物体的测量图像的相机单元和由检测光辐射的目标物体的检测图像，并且能够产生表示各测量和检测图像的输出信号 基于从相机单元输出的测量和检测到的图像，导出描述由光学干扰分量给出的干扰的干涉方程的处理器，用于基于测量图像从所测量的图像中消除光学干扰分量的计算机 干扰方程，以及用于提供的显示装置 从计算机输出的图像的视觉表示。
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