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    Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
    1.
    发明授权
    Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices 有权
    用于功能性或假性胃肠器官胃内支持的方法和装置

    公开(公告)号：US08182441B2

    公开(公告)日：2012-05-22

    申请号：US12136003

    申请日：2008-06-09

    申请人： Christopher Paul Swain ,  Cole Chen ,  Mitchell Dann ,  Greg Fluet ,  John Hancock ,  Josiah Verkaik ,  Gerard von Hoffmann ,  James Wright

    发明人： Christopher Paul Swain ,  Cole Chen ,  Mitchell Dann ,  Greg Fluet ,  John Hancock ,  Josiah Verkaik ,  Gerard von Hoffmann ,  James Wright

    IPC分类号： A61M1/36

    CPC分类号： A61F5/0076 ,  A61J15/0003 ,  A61J15/003 ,  A61J15/0049 ,  A61J15/0069 ,  A61J15/0084 ,  A61M31/00

    摘要： Disclosed herein are systems and methods for attaching or maintaining the position of a therapeutic or diagnostic device in a body lumen, such as the GI tract without necessarily requiring any penetrating attachments through any body walls. The system can include at least two elements: a proximal orientation element and a distal support element. The proximal orientation element can be configured to reside at least partially within the esophageal lumen and the distal support element can be configured to reside in the stomach, such as along the greater curve of the stomach. An intragastric support system can have a first configuration in which the long axis of the proximal orientation element is substantially parallel and/or substantially coaxial with the long axis of the distal support element, and a second configuration in which the long axis of the proximal orientation element is not substantially coaxial with the long axis of the distal support element. The second configuration can thus advantageously retain the intragastric support system in place and prevent unwanted proximal migration of the distal support element into the esophagus or distal migration into the intestine.

    摘要翻译： 本文公开了用于将治疗或诊断装置的位置附接或维持在诸如GI道的体腔中的系统和方法，而不需要通过任何身体壁的任何穿透附着物。 该系统可以包括至少两个元件：近端定向元件和远侧支撑元件。 近端定向元件可被配置为至少部分地位于食管腔内，并且远端支撑元件可被配置为驻留在胃中，例如沿着胃的较大曲线。 胃内支持系统可以具有第一构造，其中近侧定向元件的长轴基本上与远侧支撑元件的长轴平行和/或基本上同轴，并且第二构造，其中近端定向的长轴 元件基本上与远侧支撑元件的长轴同轴。 因此，第二配置可以有利地将胃内支持系统保持在适当位置，并且防止远端支撑元件进入食道的不必要的近端迁移或远端移入肠内。

    METHODS AND DEVICES FOR INTRAGASTRIC SUPPORT OF FUNCTIONAL OR PROSTHETIC GASTROINTESTINAL DEVICES
    2.
    发明申请
    METHODS AND DEVICES FOR INTRAGASTRIC SUPPORT OF FUNCTIONAL OR PROSTHETIC GASTROINTESTINAL DEVICES 有权
    用于功能性或前置性胃肠道装置的肠内支持的方法和装置

    公开(公告)号：US20090012553A1

    公开(公告)日：2009-01-08

    申请号：US12136003

    申请日：2008-06-09

    申请人： Christopher Paul Swain ,  Mitchell Dann ,  Greg Fluet ,  John Hancock ,  Gerard von Hoffmann ,  James Wright

    发明人： Christopher Paul Swain ,  Mitchell Dann ,  Greg Fluet ,  John Hancock ,  Gerard von Hoffmann ,  James Wright

    IPC分类号： A61M29/00

    CPC分类号： A61F5/0076 ,  A61J15/0003 ,  A61J15/003 ,  A61J15/0049 ,  A61J15/0069 ,  A61J15/0084 ,  A61M31/00

    摘要： Disclosed herein are systems and methods for attaching or maintaining the position of a therapeutic or diagnostic device in a body lumen, such as the GI tract without necessarily requiring any penetrating attachments through any body walls. The system can include at least two elements: a proximal orientation element and a distal support element. The proximal orientation element can be configured to reside at least partially within the esophageal lumen and the distal support element can be configured to reside in the stomach, such as along the greater curve of the stomach. An intragastric support system can have a first configuration in which the long axis of the proximal orientation element is substantially parallel and/or substantially coaxial with the long axis of the distal support element, and a second configuration in which the long axis of the proximal orientation element is not substantially coaxial with the long axis of the distal support element. The second configuration can thus advantageously retain the intragastric support system in place and prevent unwanted proximal migration of the distal support element into the esophagus or distal migration into the intestine.

    摘要翻译： 本文公开了用于将治疗或诊断装置的位置附接或维持在诸如GI道的体腔中的系统和方法，而不需要通过任何身体壁的任何穿透附着物。 该系统可以包括至少两个元件：近端定向元件和远侧支撑元件。 近端定向元件可被配置为至少部分地位于食管腔内，并且远端支撑元件可被配置为驻留在胃中，例如沿着胃的较大曲线。 胃内支持系统可以具有第一构造，其中近侧定向元件的长轴基本上与远侧支撑元件的长轴平行和/或基本上同轴，并且第二构造，其中近端定向的长轴 元件基本上与远侧支撑元件的长轴同轴。 因此，第二配置可以有利地将胃内支持系统保持在适当位置，并且防止远端支撑元件进入食道的不必要的近端迁移或远端移入肠内。

    Hydrocarbon Tank Cleaning Methods
    6.
    发明申请
    Hydrocarbon Tank Cleaning Methods 审中-公开
    烃罐清洗方法

    公开(公告)号：US20080023039A1

    公开(公告)日：2008-01-31

    申请号：US11745326

    申请日：2007-05-07

    申请人： John Hancock

    发明人： John Hancock

    IPC分类号： B08B9/093

    CPC分类号： B08B9/0933

    摘要： Systems and methods for cleaning sludge from a large tank. The sludge from the interior of storage tanks is mobilized using a metered flow agent stream and then subjected to a mechanical comminution or high shear action, e.g. by grinding or chopping. This produces a pumpable slurry which is then recirculated back into the tank to further mobilize sludge.

    摘要翻译： 从大型水箱清洗污泥的系统和方法。 使用计量流动剂流将来自储罐内部的污泥移动，然后进行机械粉碎或高剪切作用，例如， 通过研磨或切碎。 这产生可泵送浆料，然后将其再循环回罐中以进一步调节污泥。

    Biopsy apparatus
    8.
    发明申请
    Biopsy apparatus 审中-公开
    活检装置

    公开(公告)号：US20050113715A1

    公开(公告)日：2005-05-26

    申请号：US10936395

    申请日：2004-09-08

    申请人： Jeffrey Schwindt ,  Michael Miller ,  Joseph Mark ,  John Hancock ,  Charles Butcher

    发明人： Jeffrey Schwindt ,  Michael Miller ,  Joseph Mark ,  John Hancock ,  Charles Butcher

    IPC分类号： G01R33/28 ,  A61B5/055 ,  A61B10/00 ,  A61B10/02 ,  A61B17/00 ,  A61M1/00

    CPC分类号： A61B10/0275 ,  A61B10/025 ,  A61B10/0283 ,  A61B2010/0208 ,  A61B2017/00973 ,  A61B2217/005 ,  A61B2217/007

    摘要： A disposable tissue removal device comprises a “tube within a tube” cutting element mounted to a handpiece. The inner cannula of the cutting element defines an inner lumen and terminates in an inwardly beveled, razor-sharp cutting edge. The inner cannula is driven by both a pneumatic rotary motor and a pneumatic reciprocating motor. At the end of its stroke, the inner cannula makes contact with the cutting board to completely sever the tissue. An aspiration vacuum is applied to the inner lumen to aspirate excised tissue through the inner cannula and into a collection trap removably mounted to the handpiece. The rotary and reciprocating motors are hydraulically or pneumatically powered through a foot pedal operated pneumatically circuit. In one embodiment, the cutting element includes a cannula hub that can be connected to a fluid source, such as a valve-controlled saline bag.

    摘要翻译： 一次性组织去除装置包括安装到手持件的“管内管”切割元件。 切割元件的内套管限定内腔，并且终止于向内倾斜的剃刀锋利的切割边缘。 内套管由气动旋转马达和气动往复马达驱动。 在其行程结束时，内套管与切割板接触以完全切断组织。 抽吸真空被施加到内腔以通过内套管吸出切除的组织并进入到可拆卸地安装到手持件上的收集阱中。 旋转和往复式电动机通过脚踏踏板操作的气动电路进行液压或气动动力。 在一个实施例中，切割元件包括可连接到诸如阀控制的盐水袋的流体源的套管套管。

    High specific gravity intragastric device
    9.
    发明授权
    High specific gravity intragastric device 有权
    高比重胃内装置

    公开(公告)号：US08758385B2

    公开(公告)日：2014-06-24

    申请号：US12645466

    申请日：2009-12-22

    申请人： John Hancock

    发明人： John Hancock

    IPC分类号： A61M29/00

    CPC分类号： A61F5/0036 ,  A61F5/003

    摘要： The teachings are directed to an intragastric device comprising a flexible and expandable bladder having a predetermined shape upon expansion for contacting the antrum of the stomach of a subject. The device is designed to avoid passage of any part of the device beyond the pylorus and lower esophageal sphincter while the bladder is expanded during use. In these embodiments, the bladder can contain a high specific gravity material when expanded; wherein, the high specific gravity material contributes to an in vivo specific gravity of the device that ranges from about 1.2 g/ml to about 2.1 g/ml and functions to direct the device to the pyloric antrum of the subject during use of the device. Moreover, these embodiments can include a filling material comprising a biocompatible fluid component and a hydrogel component to make the device substantially leakproof and contribute to the in vivo specific gravity of the device.

    摘要翻译： 该教导涉及一种胃内装置，其包括在膨胀时具有预定形状的柔性和可膨胀囊，用于接触受试者胃的胃窦。 该装置被设计成在使用过程中膀胱膨胀时避免设备的任何部分超过幽门和食管下括约肌。 在这些实施例中，当膨胀时，气囊可以包含高比重材料; 其中，所述高比重物质有助于所述装置的体内比重为约1.2g / ml至约2.1g / ml，并且用于在使用所述装置期间将所述装置引导至所述受试者的幽门窦。 此外，这些实施方案可以包括包含生物相容性流体组分和水凝胶组分的填充材料，以使得该装置基本上防漏并有助于该装置的体内比重。