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公开(公告)号：US09409952B2
公开(公告)日：2016-08-09
申请号：US14368564
申请日：2012-12-28
发明人： Shiori Kariyuki , Takeo Iida , Miki Kojima , Ryuichi Takeyama , Mikimasa Tanada , Tetsuo Kojima , Hitoshi Iikura , Atsushi Matsuo , Takuya Shiraishi , Takashi Emura , Kazuhiko Nakano , Koji Takano , Kousuke Asou , Takuya Torizawa , Ryusuke Takano , Nozomi Hisada , Naoaki Murao , Atsushi Ohta , Kaori Kimura , Yusuke Yamagishi , Tatsuya Kato
CPC分类号： C07K7/64 , A61K38/00 , C07H21/04 , C07K1/113 , C07K5/0812 , C07K5/1013 , C07K7/06 , C07K7/08 , C07K11/00 , C07K11/02 , C07K19/00 , C12P21/02
摘要： An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.
摘要翻译： 本发明的目的是提供一种发现难以达到目标的难治性靶向药物的方法。 本发明涉及用于环化肽化合物的新方法，以及包含该肽化合物的新型肽化合物和文库，以实现上述目的。
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公开(公告)号：US11891457B2
公开(公告)日：2024-02-06
申请号：US17011815
申请日：2020-09-03
发明人： Shiori Kariyuki , Takeo Iida , Miki Kojima , Ryuichi Takeyama , Mikimasa Tanada , Tetsuo Kojima , Hitoshi Iikura , Atsushi Matsuo , Takuya Shiraishi , Takashi Emura , Kazuhiko Nakano , Koji Takano , Kousuke Asou , Takuya Torizawa , Ryusuke Takano , Nozomi Hisada , Naoaki Murao , Atsushi Ohta , Kaori Kimura , Yusuke Yamagishi , Tatsuya Kato
IPC分类号： C07K7/64 , C07K1/113 , C12P21/02 , C07K7/08 , C07K19/00 , C07H21/04 , C07K5/087 , C07K5/103 , C07K7/06 , C07K11/00 , C07K11/02 , A61K38/00
CPC分类号： C07K7/64 , C07H21/04 , C07K1/113 , C07K5/0812 , C07K5/1013 , C07K7/06 , C07K7/08 , C07K11/00 , C07K11/02 , C07K19/00 , C12P21/02 , A61K38/00
摘要： An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.
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公开(公告)号：US20150080549A1
公开(公告)日：2015-03-19
申请号：US14368564
申请日：2012-12-28
发明人： Shiori Kariyuki , Takeo Iida , Miki Kojima , Ryuichi Takeyama , Mikimasa Tanada , Tetsuo Kojima , Hitoshi Iikura , Atsushi Matsuo , Takuya Shiraishi , Takashi Emura , Kazuhiko Nakano , Koji Takano , Kousuke Asou , Takuya Torizawa , Ryusuke Takano , Nozomi Hisada , Naoaki Murao , Atsushi Ohta , Kaori Kimura , Yusuke Yamagishi , Tatsuya Kato
CPC分类号： C07K7/64 , A61K38/00 , C07H21/04 , C07K1/113 , C07K5/0812 , C07K5/1013 , C07K7/06 , C07K7/08 , C07K11/00 , C07K11/02 , C07K19/00 , C12P21/02
摘要： An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.
摘要翻译： 本发明的目的是提供一种发现难以达到目标的难治性靶向药物的方法。 本发明涉及用于环化肽化合物的新方法，以及包含该肽化合物的新型肽化合物和文库，以实现上述目的。
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公开(公告)号：US20160311858A1
公开(公告)日：2016-10-27
申请号：US15166550
申请日：2016-05-27
发明人： Shiori Kariyuki , Takeo Iida , Miki Kojima , Ryuichi Takeyama , Mikimasa Tanada , Tetsuo Kojima , Hitoshi Iikura , Atsushi Matsuo , Takuya Shiraishi , Takashi Emura , Kazuhiko Nakano , Koji Takano , Kousuke Asou , Takuya Torizawa , Ryusuke Takano , Nozomi Hisada , Naoaki Murao , Atsushi Ohta , Kaori Kimura , Yusuke Yamagishi , Tatsuya Kato
CPC分类号： C07K7/64 , A61K38/00 , C07H21/04 , C07K1/113 , C07K5/0812 , C07K5/1013 , C07K7/06 , C07K7/08 , C07K11/00 , C07K11/02 , C07K19/00 , C12P21/02
摘要： An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.
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公开(公告)号：US20210061860A1
公开(公告)日：2021-03-04
申请号：US17011815
申请日：2020-09-03
发明人： Shiori KARIYUKI , Takeo Ilda , Miki Kojima , Ryuichi Takeyama , Mikimasa Tanada , Tetsuo Kojima , Hitoshi Ilkura , Atsushi Matsuo , Takuya Shiraishi , Takashi Emura , Kazuhiko Nakano , Koji Takano , Kousuke Asou , Takuya Torizawa , Ryusuke Takano , Nozomi Hisada , Naoaki Murao , Atsushi Ohta , Kaori Kimura , Yusuke Yamagishi , Tatsuya Kato
IPC分类号： C07K7/64 , C07K1/113 , C12P21/02 , C07K7/08 , C07K19/00 , C07H21/04 , C07K5/087 , C07K5/103 , C07K7/06 , C07K11/00 , C07K11/02
摘要： An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.
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