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    Apparatus and control kit for analyzing blood sample values including hematocrit
    1.
    发明授权
    Apparatus and control kit for analyzing blood sample values including hematocrit 失效
    用于分析血液样本值（包括血细胞比容）的仪器和控制组件

    公开(公告)号：US4686479A

    公开(公告)日：1987-08-11

    申请号：US757573

    申请日：1985-07-22

    申请人： Chung C. Young ,  Robert L. Coleman ,  Sheila M. Sullivan ,  John F. Grimes ,  Ferdnand Baumeister ,  Robert MacIndoe ,  Lou Catalano ,  Pat Coppola ,  Fred Spaziani ,  Guy Rodomista ,  James E. Fowler

    发明人： Chung C. Young ,  Robert L. Coleman ,  Sheila M. Sullivan ,  John F. Grimes ,  Ferdnand Baumeister ,  Robert MacIndoe ,  Lou Catalano ,  Pat Coppola ,  Fred Spaziani ,  Guy Rodomista ,  James E. Fowler

    IPC分类号： G01N27/06 ,  G01N33/483 ,  G01N33/487 ,  G01N33/49 ,  G01N27/02

    CPC分类号： G01N33/4915

    摘要： Hematocrit level of a blood sample is measured by flowing the sample along a liquid flow path and using electrodes in the flow path to obtain electrical signals representative of the sample's electrical conductivity and of the concentration of an ion species in the path, either before or after the sample measurement. Electrical signals are obtained for standardizing solution conductivity and ion species concentration. A tentative sample hematocrit value is derived from the sample and standardizing conductivity signals. Then the tentative hematocrit value is corrected with reference to the sample and standardizing ion concentration signals and to the known standardizing solution ion concentration value. A control solution of the ion species at known concentration is used for evaluating the hematocrit detection apparatus; the solution also includes an ion activity enhancing agent. A removable septum assembly is used in a blood sample component measuring apparatus in which at least two standardizing solutions are introduced into the flow path. The septum assembly comprises: (a) chamber-defining members, which define a plurality of chambers, the members being permanently attached to each other; and (b) flexible septa positioned between the chambers, each septum having a slit, the slits being aligned to sealably receive therethrough an elongated probe connected to a flush fluid and each remaining chamber being connected to a standardizing fluid introducing lines, the septum assembly being removably attached as a unit to the apparatus which includes means for releasably attaching the septum assembly in position to receive the probe through the slits.

    摘要翻译： 血液样品的血细胞比容水平通过沿着液体流动路径流动样品并使用流动路径中的电极来测量，以获得代表样品的电导率的电信号，以及在路径之前或之后的离子种类的浓度 样品测量。 获得电信号用于标准化溶液电导率和离子种类浓度。 从样品中导出临时样品血细胞比容值，并标准化电导率信号。 然后参照样品和标准化离子浓度信号以及已知的标准溶液离子浓度值校正临时血细胞比容值。 已知浓度的离子种类的对照溶液用于评价血细胞比容检测装置; 该溶液还包括离子活性增强剂。 在血液样品成分测量装置中使用可移除的隔膜组件，其中至少两个标准化溶液被引入到流动路径中。 隔膜组件包括：（a）室限定构件，其限定多个室，所述构件永久地彼此附接; 并且（b）位于所述室之间的柔性隔垫，每个隔膜具有狭缝，所述狭缝对准以可密封地容纳其中连接到冲洗流体的细长探针，并且每个剩余室连接到标准化流体引入管线，所述隔膜组件 可移除地附接到装置上，该装置包括用于将隔膜组件可释放地附接到适当位置以接收穿过狭缝的探针的装置。