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公开(公告)号：US20100276582A1
公开(公告)日：2010-11-04
申请号：US12431896
申请日：2009-04-29
申请人： Chung Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
发明人： Chung Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
CPC分类号： H05H5/047 , H01J49/06 , H01J49/40 , H01J49/403
摘要： A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.
摘要翻译： 提供了一种用于加速分析物的新系统和方法，包括但不限于分子离子，生物分子，聚合物，纳米和微粒。 本发明可用于在诸如质谱法，进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。
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公开(公告)号：US08344317B2
公开(公告)日：2013-01-01
申请号：US13365105
申请日：2012-02-02
申请人： Chung-Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
发明人： Chung-Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
CPC分类号： H05H5/047 , H01J49/06 , H01J49/40 , H01J49/403
摘要： A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.
摘要翻译： 提供了一种用于加速分析物的新系统和方法，包括但不限于分子离子，生物分子，聚合物，纳米和微粒。 本发明可用于在诸如质谱法，进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。
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公开(公告)号：US20120126112A1
公开(公告)日：2012-05-24
申请号：US13365105
申请日：2012-02-02
申请人： Chung Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
发明人： Chung Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
CPC分类号： H05H5/047 , H01J49/06 , H01J49/40 , H01J49/403
摘要： A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.
摘要翻译： 提供了一种用于加速分析物的新系统和方法，包括但不限于分子离子，生物分子，聚合物，纳米和微粒。 本发明可用于在诸如质谱法，进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。
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公开(公告)号：US08138472B2
公开(公告)日：2012-03-20
申请号：US12431896
申请日：2009-04-29
申请人： Chung Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
发明人： Chung Hsuan Chen , Jung-Lee Lin , Nien-Yeen Hsu , Yi-Sheng Wang
IPC分类号： H01J49/40
CPC分类号： H05H5/047 , H01J49/06 , H01J49/40 , H01J49/403
摘要： A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.
摘要翻译： 提供了一种用于加速分析物的新系统和方法，包括但不限于分子离子，生物分子，聚合物，纳米和微粒。 本发明可用于在诸如质谱法，进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。
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公开(公告)号：US08309913B2
公开(公告)日：2012-11-13
申请号：US12689506
申请日：2010-01-19
申请人： Yi-Sheng Wang , Chung-Hsuan Chen
发明人： Yi-Sheng Wang , Chung-Hsuan Chen
IPC分类号： H01J49/10
CPC分类号： H01J49/40 , H01J49/0095
摘要： An angled dual-polarity mass spectrometer includes a dual-polarity ion generator, a first mass analyzer, and a second mass analyzer. The dual-polarity ion generator includes an ion source to generate positive ions and negative ions from a sample, and electrodes to generate electric fields for guiding the negative ions into a beam of negative ions and guiding the positive ions into a beam of positive ions. The first mass analyzer can analyze the negative ions, and the second mass analyzer can analyze the positive ions. The central axes of the first and the second mass analyzers are at an angle between 0 to 179 degrees.
摘要翻译： 角度双极性质谱仪包括双极性离子发生器，第一质量分析器和第二质量分析器。 双极性离子发生器包括从样品产生正离子和负离子的离子源，以及用于产生电场的电极，用于将负离子引导到负离子束中并将正离子引导到正离子束中。 第一个质谱仪可以分析负离子，第二个质谱仪可以分析正离子。 第一和第二质量分析器的中心轴线在0至179度之间的角度。
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公开(公告)号：US07649170B2
公开(公告)日：2010-01-19
申请号：US11542568
申请日：2006-10-03
IPC分类号： H01J49/10
CPC分类号： H01J49/40 , H01J49/0095
摘要： A dual-polarity mass spectrometer includes an ion source, a negative ion mass analyzer, and a positive ion mass analyzer to measure both the negative and positive ion spectra of a sample material simultaneously. The ion source includes a sample surface on which the sample material is positioned, the sample material providing positive ions and negative ions when excited by a laser beam or an energetic particle stream. A first extraction electrode is connected to a voltage higher than the sample surface to attract the negative ions from the sample electrode. A second extraction electrode is connected to a voltage lower than the sample surface to attract the positive ions from the sample electrode. The negative and positive ions are analyzed simultaneously by the negative ion mass analyzer and the positive ion mass analyzer, respectively.
摘要翻译： 双极性质谱仪包括离子源，负离子质量分析仪和正离子质量分析仪，以同时测量样品材料的负离子和正离子光谱。 离子源包括其上放置样品材料的样品表面，当由激光束或能量粒子流激发时，样品材料提供正离子和负离子。 第一引出电极连接到高于样品表面的电压以吸引来自样品电极的负离子。 第二提取电极连接到低于样品表面的电压，以吸引来自样品电极的正离子。 负离子和正离子分别通过负离子质量分析仪和正离子质量分析仪同时分析。
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公开(公告)号：US20100181474A1
公开(公告)日：2010-07-22
申请号：US12689506
申请日：2010-01-19
申请人： Yi-Sheng Wang , Chung-Hsuan Chen
发明人： Yi-Sheng Wang , Chung-Hsuan Chen
CPC分类号： H01J49/40 , H01J49/0095
摘要： An angled dual-polarity mass spectrometer includes a dual-polarity ion generator, a first mass analyzer, and a second mass analyzer. The dual-polarity ion generator includes an ion source to generate positive ions and negative ions from a sample, and electrodes to generate electric fields for guiding the negative ions into a beam of negative ions and guiding the positive ions into a beam of positive ions. The first mass analyzer can analyze the negative ions, and the second mass analyzer can analyze the positive ions. The central axes of the first and the second mass analyzers are at an angle between 0 to 179 degrees.
摘要翻译： 角度双极性质谱仪包括双极性离子发生器，第一质量分析器和第二质量分析器。 双极性离子发生器包括从样品产生正离子和负离子的离子源，以及用于产生电场的电极，用于将负离子引导到负离子束中并将正离子引导到正离子束中。 第一个质谱仪可以分析负离子，第二个质谱仪可以分析正离子。 第一和第二质量分析器的中心轴线在0至179度之间的角度。
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公开(公告)号：US20080078928A1
公开(公告)日：2008-04-03
申请号：US11542568
申请日：2006-10-03
IPC分类号： H01J49/40
CPC分类号： H01J49/40 , H01J49/0095
摘要： A dual-polarity mass spectrometer includes an ion source, a negative ion mass analyzer, and a positive ion mass analyzer to measure both the negative and positive ion spectra of a sample material simultaneously. The ion source includes a sample surface on which the sample material is positioned, the sample material providing positive ions and negative ions when excited by a laser beam or an energetic particle stream. A first extraction electrode is connected to a voltage higher than the sample surface to attract the negative ions from the sample electrode. A second extraction electrode is connected to a voltage lower than the sample surface to attract the positive ions from the sample electrode. The negative and positive ions are analyzed simultaneously by the negative ion mass analyzer and the positive ion mass analyzer, respectively.
摘要翻译： 双极性质谱仪包括离子源，负离子质量分析仪和正离子质量分析仪，以同时测量样品材料的负离子和正离子光谱。 离子源包括其上放置样品材料的样品表面，当由激光束或能量粒子流激发时，样品材料提供正离子和负离子。 第一引出电极连接到高于样品表面的电压以吸引来自样品电极的负离子。 第二提取电极连接到低于样品表面的电压，以吸引来自样品电极的正离子。 负离子和正离子分别通过负离子质量分析仪和正离子质量分析仪同时分析。
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公开(公告)号：US07714299B2
公开(公告)日：2010-05-11
申请号：US11501142
申请日：2006-08-08
申请人： Yi-Sheng Wang , Shang-Ting Tsai
发明人： Yi-Sheng Wang , Shang-Ting Tsai
IPC分类号： H01J37/244
CPC分类号： G01T1/362 , H01J49/025 , H01J2237/244
摘要： A particle detector for detecting a particle beam includes a negatively charged electrode plate having a first side facing the particle beam, a second side opposite to the first side, and a through-hole extending from the first side to the second side for receiving the particle beam. A detection device adjacent to the second side of the electrode plate detects signals corresponding to the particle beam approaching the through-hole.
摘要翻译： 用于检测粒子束的粒子检测器包括具有面向粒子束的第一侧的带负电荷的电极板，与第一侧相对的第二侧，以及从第一侧延伸到第二侧的用于接收粒子的通孔 光束。 与电极板的第二侧相邻的检测装置检测与接近通孔的粒子束相对应的信号。
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10.发明授权Adaptive pitch pulse enhancer and method for use in a codebook excited linear predicton (Celp) search loop 失效自适应音调脉冲增强器和用于码本激励线性预测（Celp）搜索循环的方法
公开(公告)号：US5528727A
公开(公告)日：1996-06-18
申请号：US434096
申请日：1995-05-03
申请人： Yi-Sheng Wang
发明人： Yi-Sheng Wang
摘要： An adaptive pitch pulse enhancer and method, adaptive to a voicing measure of input speech, for modifying the adaptive codebook of a CELP search loop to enhance the pitch pulse structure of the adaptive codebook. The adaptive pitch pulse enhancer determines a voicing measure of an input signal, the voicing measure being voiced when the input signal includes voiced speech and the voicing measure being unvoiced when the input signal does not include voiced speech, modifies a total excitation vector produced by the CELP search loop in accordance with the voicing measure of the input signal, and updates the adaptive codebook of the CELP search loop by storing the modified total excitation vector in the adaptive codebook.
摘要翻译： 一种自适应音调脉冲增强器和方法，适用于输入语音的语音测量，用于修改CELP搜索循环的自适应码本以增强自适应码本的音调脉冲结构。 自适应音调脉冲增强器确定输入信号的发声测量，当输入信号包括有声语音时，发声测量被发音，并且当输入信号不包括有声语音时，语音测量是无声的，修改由 CELP搜索循环，并且通过将修改的总激励矢量存储在自适应码本中来更新CELP搜索循环的自适应码本。
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