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公开(公告)号：US20140335564A1
公开(公告)日：2014-11-13
申请号：US14258994
申请日：2014-04-22
申请人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号： C07K16/24
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号：US20140343267A1
公开(公告)日：2014-11-20
申请号：US14261257
申请日：2014-04-24
申请人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译： 与用于治疗，预防和诊断IL-17相关疾病和用于检测细胞，组织，样品和组合物中的IL-17的组合物和方法一起描述了结合IL-17和/或IL-17F的蛋白质。
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公开(公告)号：US20140348834A1
公开(公告)日：2014-11-27
申请号：US14260197
申请日：2014-04-23
申请人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号： C07K16/24 , C07K16/46 , A61K39/395
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号：US20140017246A1
公开(公告)日：2014-01-16
申请号：US13959648
申请日：2013-08-05
申请人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号： C07K16/24
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号：US20140356909A1
公开(公告)日：2014-12-04
申请号：US14263724
申请日：2014-04-28
申请人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
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公开(公告)号：US08779101B2
公开(公告)日：2014-07-15
申请号：US13959648
申请日：2013-08-05
申请人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号： A61K39/00
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译： 与用于治疗，预防和诊断IL-17相关疾病和用于检测细胞，组织，样品和组合物中的IL-17的组合物和方法一起描述了结合IL-17和/或IL-17F的蛋白质。
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公开(公告)号：US20140348856A1
公开(公告)日：2014-11-27
申请号：US14262653
申请日：2014-04-25
申请人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
发明人： Chung-Ming Hsieh , Margaret Hugunin , Anwar Murtaza , Bradford L. McRae , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers , Craig Wallace , Shaughn H. Bryant , Mary R. Leddy
IPC分类号： C07K16/24
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译： 描述了结合IL-17和/或IL-17F的蛋白质及其在用于治疗，预防和诊断IL-17相关疾病和用于检测细胞，组织，样品和组合物中的IL-17的组合物和方法中的用途。
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公开(公告)号：US08835610B2
公开(公告)日：2014-09-16
申请号：US12718841
申请日：2010-03-05
申请人： Chung-Ming Hsieh , Margaret Hugunin , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers
发明人： Chung-Ming Hsieh , Margaret Hugunin , Yuliya Kutskova , John E. Memmott , Jennifer M. Perez , Suju Zhong , Edit Tarcsa , Anca Clabbers
IPC分类号： A61K39/395 , C07K16/24
CPC分类号： C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
摘要： Proteins that bind IL-17 and/or IL-17F are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
摘要翻译： 描述了结合IL-17和/或IL-17F的蛋白质及其在用于治疗，预防和诊断IL-17相关疾病和用于检测细胞，组织，样品和组合物中的IL-17的组合物和方法中的用途。
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公开(公告)号：US20090311253A1
公开(公告)日：2009-12-17
申请号：US12477711
申请日：2009-06-03
申请人： Tariq Ghayur , Peter C. Isakson , Lisa M. Olson , Chengbin Wu , Margaret Hugunin , Rajesh V. Kamath , Carolyn A. Cuff , Hamish J. Allen
发明人： Tariq Ghayur , Peter C. Isakson , Lisa M. Olson , Chengbin Wu , Margaret Hugunin , Rajesh V. Kamath , Carolyn A. Cuff , Hamish J. Allen
IPC分类号： A61K39/395 , C07K16/00 , C07H21/04 , C12N15/63 , C12N1/21 , C12N1/10 , C12N5/10 , C12N1/15 , C12P21/06
CPC分类号： C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545 , Y02A50/386 , Y02A50/41 , Y02A50/412
摘要： The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
摘要翻译： 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，具体涉及用于预防，诊断和/或治疗疾病的用途。
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公开(公告)号：US09035027B2
公开(公告)日：2015-05-19
申请号：US12477711
申请日：2009-06-03
申请人： Tariq Ghayur , Peter C. Isakson , Lisa M. Olson , Chengbin Wu , Margaret Hugunin , Rajesh V. Kamath , Carolyn A. Cuff , Hamish J. Allen
发明人： Tariq Ghayur , Peter C. Isakson , Lisa M. Olson , Chengbin Wu , Margaret Hugunin , Rajesh V. Kamath , Carolyn A. Cuff , Hamish J. Allen
IPC分类号： A61K39/395 , C07K16/46 , C07K16/22 , C07K16/24 , A61K45/06 , A61K47/48 , G01N33/68 , A61K39/00
CPC分类号： C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545 , Y02A50/386 , Y02A50/41 , Y02A50/412
摘要： The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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