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公开(公告)号:US20100261714A1
公开(公告)日:2010-10-14
申请号:US12756276
申请日:2010-04-08
申请人: Claudio STURINO , Patrick DEROY , Martin DUPLESSIS , Paul J. EDWARDS , Anne-Marie FAUCHER , Teddy HALMOS , Clint JAMES , Jean-Eric LACOSTE , Eric MALENFANT , Joannie MINVILLE , Louis MORENCY , Sebastien MORIN , Martin TREMBLAY , Christiane YOAKIM
发明人: Claudio STURINO , Patrick DEROY , Martin DUPLESSIS , Paul J. EDWARDS , Anne-Marie FAUCHER , Teddy HALMOS , Clint JAMES , Jean-Eric LACOSTE , Eric MALENFANT , Joannie MINVILLE , Louis MORENCY , Sebastien MORIN , Martin TREMBLAY , Christiane YOAKIM
IPC分类号: A61K31/519 , C07D491/048 , C07D413/14 , A61K31/5377 , A61K31/496 , C07D495/04 , A61K31/542 , A61P31/18 , A61K31/497
CPC分类号: C07D491/048 , C07D487/04 , C07D491/147 , C07D513/04 , C07D519/00
摘要: Compounds of formula (I): wherein R1, R2, A1, A2, A3, A4, X and Y are as defined herein, are useful as inhibitors of HIV replication.
摘要翻译: 式(I)化合物:其中R1,R2,A1,A2,A3,A4,X和Y如本文所定义,可用作HIV复制的抑制剂。
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公开(公告)号:US20090143370A1
公开(公告)日:2009-06-04
申请号:US12364551
申请日:2009-02-03
申请人: Patrick DeROY , Anne-Marie FAUCHER , Alexandre GAGNON , Serge LANDRY , Sebastien MORIN , Jeffrey O'MEARA , Bruno SIMONEAU , Bounkham THAVONEKHAM , Christiane YOAKIM
发明人: Patrick DeROY , Anne-Marie FAUCHER , Alexandre GAGNON , Serge LANDRY , Sebastien MORIN , Jeffrey O'MEARA , Bruno SIMONEAU , Bounkham THAVONEKHAM , Christiane YOAKIM
IPC分类号: A61K31/541 , C07D257/04 , A61K31/41 , A61K31/4439 , A61P31/18 , C07D401/12 , C07D417/12
CPC分类号: C07D257/04 , A61K31/41 , A61K31/4439 , A61K31/454 , A61K31/4709 , A61K31/495 , A61K31/5377 , A61K31/541 , C07D231/18 , C07D233/84 , C07D249/08 , C07D249/12 , C07D277/36 , C07D285/06 , C07D285/125 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12
摘要: Compounds of formula (I): wherein Ar, X, R1, R2, R3 and R4 are as defined herein. The compounds are useful as reverse transcriptase inhibitors against wild type and single or double mutant strains of HIV.
摘要翻译: 式(I)化合物:其中Ar,X,R 1,R 2,R 3和R 4如本文所定义。 该化合物可用作针对野生型和单突变或双突变株的逆转录酶抑制剂。
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