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公开(公告)号:US20070123549A1
公开(公告)日:2007-05-31
申请号:US11561926
申请日:2006-11-21
申请人: Deirdre Hickey , Robert Ife , Colin Leach , Ivan Pinto , Stephen Smith , Steven Stanway
发明人: Deirdre Hickey , Robert Ife , Colin Leach , Ivan Pinto , Stephen Smith , Steven Stanway
IPC分类号: A61K31/513 , C07D239/47
CPC分类号: C07D239/56 , C07D239/60 , C07D239/70 , C07D239/95 , C07D401/12 , C07D403/12 , C07D495/04
摘要: Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in treating atheroscelerosis.
摘要翻译: 式(I)的嘧啶酮化合物:是Lp-PLA 2酶的抑制剂,可用于治疗动脉粥样硬化。
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公开(公告)号:US20050014793A1
公开(公告)日:2005-01-20
申请号:US10900489
申请日:2004-07-28
申请人: Deirdre Hickey , Robert Ife , Colin Leach , John Liddle , Ivan Pinto , Stephen Smith , Steven Stanway
发明人: Deirdre Hickey , Robert Ife , Colin Leach , John Liddle , Ivan Pinto , Stephen Smith , Steven Stanway
IPC分类号: C07D215/20 , A61K31/435 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/47 , A61K31/4709 , A61P3/10 , A61P9/00 , A61P9/10 , A61P19/02 , A61P29/00 , C07D211/74 , C07D215/36 , C07D221/04 , C07D401/12 , C07D471/04 , C07D495/04 , C07D513/04 , A61K31/4439 , C07
CPC分类号: C07D221/04 , C04B35/632 , C07D211/74 , C07D215/36 , C07D401/12 , C07D471/04 , C07D495/04 , C07D513/04
摘要: Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis. Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
摘要翻译: 式(I)化合物:是Lp-PLA2酶的抑制剂,可用于治疗,特别是治疗动脉粥样硬化。 式(I)化合物:是Lp-PLA2酶的抑制剂,可用于治疗,特别是治疗动脉粥样硬化。
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公开(公告)号:US20050043335A1
公开(公告)日:2005-02-24
申请号:US10494509
申请日:2002-11-08
申请人: Richard Elliott , Deidre Hickey , Robert Ife , Colin Leach , John Liddle , Ivan Pinto , Stephen Smith , Steven Stanway
发明人: Richard Elliott , Deidre Hickey , Robert Ife , Colin Leach , John Liddle , Ivan Pinto , Stephen Smith , Steven Stanway
IPC分类号: C07D215/22 , A61K31/47 , A61K31/4709 , A61K31/5377 , A61P3/10 , A61P9/10 , A61P9/12 , A61P17/06 , A61P19/02 , A61P29/00 , A61P43/00 , C07D215/06 , C07D215/233 , C07D401/12 , C07D413/12 , C07D471/02 , A61K31/517 , A61K31/519
CPC分类号: C07D215/233
摘要: Compounds of the formula (I) are inhibitors of the enzyme Lp-PLA2? and are of use in therapy, in particular for treating atherosclerosis.
摘要翻译: 式(I)的化合物是酶抑制剂Lp-PLA
2? 并且用于治疗,特别是用于治疗动脉粥样硬化。 -
公开(公告)号:US20050033052A1
公开(公告)日:2005-02-10
申请号:US10495025
申请日:2002-11-08
申请人: Colin Leach , Ivan Pinto , Stephen Smith , Steven Stanway
发明人: Colin Leach , Ivan Pinto , Stephen Smith , Steven Stanway
IPC分类号: A61K31/519 , A61P3/10 , A61P9/10 , A61P9/12 , C07D495/04 , C07D213/69 , C07D239/02
CPC分类号: C07D495/04
摘要: Pyrimidone and pyridone compounds of the formula: are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
摘要翻译: 下式的嘧啶酮和吡啶酮化合物是Lp-PLA2酶的抑制剂,可用于治疗,特别是用于治疗动脉粥样硬化。
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公开(公告)号:US20070155762A1
公开(公告)日:2007-07-05
申请号:US11561035
申请日:2006-11-17
申请人: Colin Leach , Stephen Smith , Steven Stanway
发明人: Colin Leach , Stephen Smith , Steven Stanway
IPC分类号: A61K31/513 , A61K31/401 , A61K31/366 , A61K31/22
CPC分类号: C07D239/56 , C07D239/60 , C07D239/70 , C07D239/95 , C07D401/12 , C07D403/12 , C07D495/04
摘要: Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in treating atheroscelerosis.
摘要翻译: 式(I)的嘧啶酮化合物:是Lp-PLA 2酶的抑制剂,可用于治疗动脉粥样硬化。
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6.Pyridone, pyridazone and triazone derivatives as lp-pla2 inhibitors 审中-公开
标题翻译: 吡啶酮,哒嗪酮和三嗪衍生物作为lp-pla2抑制剂公开(公告)号:US20050020832A1
公开(公告)日:2005-01-27
申请号:US10495022
申请日:2002-11-08
申请人: Stephen Fell , Deirdre Hickey , Colin Leach , John Liddle , Ivan Pinto , Stephen Smith
发明人: Stephen Fell , Deirdre Hickey , Colin Leach , John Liddle , Ivan Pinto , Stephen Smith
IPC分类号: A61K31/501 , A61P9/10 , A61P17/06 , A61P29/00 , C07D401/12 , C07D401/14 , C07D237/02 , C07D241/02
CPC分类号: C07D401/12 , C07D401/14
摘要: Compounds of the formula (I) are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
摘要翻译: 式(I)的化合物是Lp-PLA2酶的抑制剂,并且在治疗中尤其用于治疗动脉粥样硬化。
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7.Pyrimidinone Derivatives and Their Use in the Treatment of Atherosclerosis 失效
标题翻译: 嘧啶酮衍生物及其在治疗动脉粥样硬化中的应用公开(公告)号:US20060241126A1
公开(公告)日:2006-10-26
申请号:US11456129
申请日:2006-07-07
申请人: Richard Elliott , Deirdre Hickey , Robert Ife , Colin Leach , Ivan Pinto , Stephen Smith
发明人: Richard Elliott , Deirdre Hickey , Robert Ife , Colin Leach , Ivan Pinto , Stephen Smith
IPC分类号: A61K31/519 , C07D239/70
CPC分类号: C07D239/36 , C07D239/70 , C07D239/91 , C07D401/12 , C07D403/12 , C07D409/14 , C07D471/04 , C07D487/04 , C07D495/04
摘要: Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
摘要翻译: 式(I)化合物:是Lp-PLA 2酶的抑制剂,可用于治疗,特别是用于治疗动脉粥样硬化。
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8.N-substituted pyridinone and pyrimidinone derivatives for use as lp-pla2 inhibitors in the treatment of artherosclerosis 审中-公开
标题翻译: N-取代的吡啶酮和嘧啶酮衍生物用作治疗动脉粥样硬化的lp-pla2抑制剂公开(公告)号:US20050245552A1
公开(公告)日:2005-11-03
申请号:US10510467
申请日:2003-04-10
申请人: Colin Leach , Stephen Smith
发明人: Colin Leach , Stephen Smith
IPC分类号: A61K31/4545 , A61K31/4709 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , A61P17/06 , A61P19/02 , A61P25/28 , A61P29/00 , A61P31/04 , A61P43/00 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D471/04 , A61K31/513 , A61K31/4415 , A61K31/4439 , C07D211/72 , C07D43/02
CPC分类号: C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D471/04
摘要: Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis. In Formula I R1, R2, R3, R4, R5, R6, X and Y.
摘要翻译: 式(I)化合物:是Lp-PLA 2酶的抑制剂,可用于治疗,特别是用于治疗动脉粥样硬化。 在式IR 1中,R 2,R 3,R 4,R 5,..., R 6,X和Y。
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公开(公告)号:USD985695S1
公开(公告)日:2023-05-09
申请号:US29795137
申请日:2021-06-17
申请人: Stephen Smith
设计人: Stephen Smith
摘要: FIG. 1 is a right perspective view of a water rower showing the new design.
FIG. 2 is a rear view thereof.
FIG. 3 is a front view thereof.
FIG. 4 is a left side view thereof; and,
FIG. 5 is a right side view thereof.
The broken lines in the drawings depict portions of the water rower that form no part of the claimed design.-
公开(公告)号:US20220224993A2
公开(公告)日:2022-07-14
申请号:US17114186
申请日:2020-12-07
申请人: Brick Eksten , Stephen Smith , Yuval Fisher , Steven Reynolds
发明人: Brick Eksten , Stephen Smith , Yuval Fisher , Steven Reynolds
IPC分类号: H04N21/845 , H04N21/262 , H04N21/2343 , H04N21/24 , H04L29/06 , H04N21/458 , H04N21/488
摘要: A system for producing fragmented video content is provided. The system includes a processing device, a non-transitory data store, and a memory storage device having at least a Manifest Processing Service (MPS) unit stored therein. The MPS unit is configured to generate at least one master manifest and store the master manifest in the non-transitory data store, the master manifest comprising a timing reference for a video fragment of the fragmented video content, wherein the timing reference indicates a temporal boundary of processing for the video fragment.
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