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11 条记录 (耗时 0.02 秒)

    CASPASE INHIBITORS
    1.
    发明申请
    CASPASE INHIBITORS 有权
    CASPASE抑制剂

    公开(公告)号：US20120294843A1

    公开(公告)日：2012-11-22

    申请号：US13575273

    申请日：2011-01-27

    申请人： Craig Thomas ,  Matthew B. Boxer

    发明人： Craig Thomas ,  Matthew B. Boxer

    IPC分类号： A61K38/54 ,  C12N9/96 ,  A61P29/00 ,  A61P19/08 ,  A61K38/06 ,  C07K5/08 ,  C12N9/99 ,  A61P31/00

    CPC分类号： C07K5/06034 ,  C07K5/06026 ,  C07K5/06191

    摘要： A compound, or a pharmaceutically acceptable salt or ester thereof, of formula I: X—W wherein X is a caspase-selective structure and W has the structure of —NH—CH(Y)(Z) wherein Y is a structure that can form a reversible covalent bond with a caspase; and Z is selected from a carboxyl moiety or a carboxylic acid mimetic.

    摘要翻译： 式I的化合物或其药学上可接受的盐或酯：X-W其中X是胱天蛋白酶选择性结构，W具有-NH-CH（Y）（Z）的结构，其中Y是可以 与半胱天冬酶形成可逆共价键; Z选自羧基部分或羧酸模拟物。

    Caspase inhibitors
    2.
    发明授权
    Caspase inhibitors 有权
    胱天蛋白酶抑制剂

    公开(公告)号：US09365612B2

    公开(公告)日：2016-06-14

    申请号：US13575273

    申请日：2011-01-27

    申请人： Craig Thomas ,  Matthew B. Boxer

    发明人： Craig Thomas ,  Matthew B. Boxer

    IPC分类号： C07D207/00 ,  C07D295/00 ,  C07K5/062 ,  C07K5/06

    CPC分类号： C07K5/06034 ,  C07K5/06026 ,  C07K5/06191

    摘要： A compound, or a pharmaceutically acceptable salt or ester thereof, of formula I: X—W wherein X is a caspase-selective structure and W has the structure of —NH—CH(Y)(Z) wherein Y is a structure that can form a reversible covalent bond with a caspase; and Z is selected from a carboxyl moiety or a carboxylic acid mimetic.

    摘要翻译： 式I的化合物或其药学上可接受的盐或酯：X-W其中X是胱天蛋白酶选择性结构，W具有-NH-CH（Y）（Z）的结构，其中Y是可以 与半胱天冬酶形成可逆共价键; Z选自羧基部分或羧酸模拟物。

    ATTACHABLE CANOPY FOR RIDING LAWNMOWER
    5.
    发明申请
    ATTACHABLE CANOPY FOR RIDING LAWNMOWER 审中-公开

    公开(公告)号：US20170341495A1

    公开(公告)日：2017-11-30

    申请号：US15168769

    申请日：2016-05-31

    申请人： Craig Thomas

    发明人： Craig Thomas

    IPC分类号： B60J7/10

    CPC分类号： A01D34/00

    摘要： An attachable canopy for a riding lawnmower for providing a shading mechanism for a user seated on such a lawnmower includes a harness formed from a wrap around elongated strap that has a first end that is connectable to a second end, a frame which includes two elongated rods whose proximal ends are connected to opposite sides of the harness, and a canopy which is connected to the distal ends of the rods. The harness is adjustable so as to be attachable to either the seat or seat back of a riding lawnmower. In this regard, the rods which form the frame may selectively swivel at least ninety degrees so as to remain in a perpendicular orientation relative to the seat with the canopy held over the seat regardless of which structure the harness is attached to.

    Attachable canopy for riding lawnmower
    8.
    发明授权
    Attachable canopy for riding lawnmower 有权

    公开(公告)号：US09889727B2

    公开(公告)日：2018-02-13

    申请号：US15168769

    申请日：2016-05-31

    申请人： Craig Thomas

    发明人： Craig Thomas

    IPC分类号： B60J7/10

    CPC分类号： A01D34/00

    摘要： An attachable canopy for a riding lawnmower for providing a shading mechanism for a user seated on such a lawnmower includes a harness formed from a wrap around elongated strap that has a first end that is connectable to a second end, a frame which includes two elongated rods whose proximal ends are connected to opposite sides of the harness, and a canopy which is connected to the distal ends of the rods. The harness is adjustable so as to be attachable to either the seat or seat back of a riding lawnmower. In this regard, the rods which form the frame may selectively swivel at least ninety degrees so as to remain in a perpendicular orientation relative to the seat with the canopy held over the seat regardless of which structure the harness is attached to.

    TAPERED DROP BOX
    10.
    发明申请
    TAPERED DROP BOX 审中-公开
    圆锥滚筒

    公开(公告)号：US20070149063A1

    公开(公告)日：2007-06-28

    申请号：US11612338

    申请日：2006-12-18

    申请人： Craig Thomas

    发明人： Craig Thomas

    IPC分类号： H01R13/502

    CPC分类号： B65F3/26 ,  B60P1/26 ,  B60P1/286 ,  B65D88/025 ,  B65D88/123 ,  B65D90/008 ,  B65D90/027

    摘要： One embodiment of the disclosed drop box comprises end wall portions that taper from a first end to a second end, such as being wider adjacent to an open top portion and narrower adjacent to a bottom wall. The end walls are coupled to the bottom wall, which also tapers from a first end to a second end, such as tapering from a wide end adjacent to a front end wall to a narrower end adjacent to a back end wall. The drop box thus can have a taper in a first direction and a taper in a second direction. These tapers in the first and second directions can be sized and shaped as desired and to allow a first drop box to be nested with a second drop box, such as for transport or storage.

    摘要翻译： 所公开的液滴箱的一个实施例包括端壁部分，其从第一端部到第二端部逐渐变细，例如在开口顶部部分附近变宽并且邻近底壁更窄。 端壁连接到底壁，底壁也从第一端逐渐变细到第二端，例如从邻近前端壁的较宽端部逐渐变细到邻近后端壁的较窄端部。 因此，下落盒可以在第一方向上具有锥形并且在第二方向上具有锥形。 在第一和第二方向上的这些锥形可以根据需要进行大小和成形，并允许第一下降箱与第二液滴盒嵌套，例如用于运输或储存。