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公开(公告)号:US20210241866A1
公开(公告)日:2021-08-05
申请号:US17163438
申请日:2021-01-30
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
Abstract: A method for trial design includes presenting on a graphical interface, a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs. The method further includes: monitoring a first set of user interactions with the set of cards; determining a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions; and presenting on the graphical interface a new card that is representative of a trial design consistent with the determined user preference. The method may also include monitoring a second set of user interactions with the new card and refining the determined user preference based at least in part on the second set of user interactions with the new card.
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公开(公告)号:US20210241860A1
公开(公告)日:2021-08-05
申请号:US17163425
申请日:2021-01-30
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
Abstract: A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.
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公开(公告)号:US20210241144A1
公开(公告)日:2021-08-05
申请号:US17163427
申请日:2021-01-30
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
Abstract: A method, according to some implementations, includes obtaining trial design simulation results for a set of trial designs and determining a set of Pareto designs in the set of trial designs based at least in part on the trial design simulation results and one or more performance parameters. The method further includes determining a set of convex hull designs in the set of trial designs, determining a set of recommended designs based at least in part on the set of Pareto designs and the set of convex hull designs, and transmitting the set of recommended designs.
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公开(公告)号:US20240404657A1
公开(公告)日:2024-12-05
申请号:US18735449
申请日:2024-06-06
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharyya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
IPC: G16H10/20 , G06F30/10 , G06F30/12 , G06F30/20 , G06F111/02 , G06F111/04 , G06F111/06 , G06F111/08 , G06F111/16 , G06N5/04 , G06N20/00 , G06Q10/0631 , G06Q10/067 , G06Q30/0204 , G16H40/20 , G16H50/70
Abstract: A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.
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公开(公告)号:US20220375551A1
公开(公告)日:2022-11-24
申请号:US17847057
申请日:2022-06-22
Applicant: Cytel Inc.
Inventor: Nitin Patel , Jaydeep Bhattacharyya , Albert M. Kim , Yannis Jemiai , Jay Kyle Wathen , Sagar Mehta , Christopher Michael Porayko
IPC: G16H10/20 , G06F30/20 , G06Q10/06 , G06F30/12 , G16H40/20 , G16H50/70 , G06N20/00 , G06Q30/02 , G06F30/10 , G06N5/04
Abstract: A method and system including identifying, via at least one processor, a user role; configuring, via the at least one processor, an interface for the user role, wherein configuring the interface includes determining an interface view for the user role; and displaying, via the at least one processor, the interface with the interface view.
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公开(公告)号:US20210241859A1
公开(公告)日:2021-08-05
申请号:US17163423
申请日:2021-01-30
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
Abstract: A method for determining trial designs is provided. The method includes obtaining simulation data for a set of trial designs. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria; determining an optimality criteria for evaluating the trial designs; searching, within the set of trial designs, for globally optimum designs based on the optimality criteria; and recommending globally optimum designs.
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公开(公告)号:US20210240883A1
公开(公告)日:2021-08-05
申请号:US17163424
申请日:2021-01-30
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
Abstract: A method, according to some implementations, includes obtaining a criteria for a trial design study, determining permutations for designs in response to the criteria, and determining permutations for scenarios in response to the criteria. The method may further include generating combinations of the permutations for the designs and the permutations for the scenarios, simulating designs corresponding to the generated combinations, and determining performance of the simulated designs.
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公开(公告)号:US12051488B2
公开(公告)日:2024-07-30
申请号:US17163438
申请日:2021-01-30
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharyya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
IPC: G16H10/20 , G06F30/27 , G06N5/04 , G06N20/00 , G06Q10/067 , G06Q10/101 , G16H40/20 , G16H50/50 , G06F3/0484 , G06F111/06
CPC classification number: G16H10/20 , G06F30/27 , G06N5/04 , G06N20/00 , G06Q10/067 , G06Q10/101 , G16H40/20 , G16H50/50 , G06F3/0484 , G06F2111/06
Abstract: A method for trial design includes presenting on a graphical interface, a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs. The method further includes: monitoring a first set of user interactions with the set of cards; determining a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions; and presenting on the graphical interface a new card that is representative of a trial design consistent with the determined user preference. The method may also include monitoring a second set of user interactions with the new card and refining the determined user preference based at least in part on the second set of user interactions with the new card.
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公开(公告)号:US20210319158A1
公开(公告)日:2021-10-14
申请号:US17354639
申请日:2021-06-22
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharyya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
Abstract: A method, according to some implementations, includes generating a plurality of base datasets using a random number generator and determining scenario specifications. The method may further include identifying at least one transformation function for at least one of the plurality of base datasets based on the scenario specifications and transforming the at least one of the plurality of base datasets using the at least one transformation function. In some cases, the method may also include generating scenario parameters based on the at least one transformed datasets.
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公开(公告)号:US20210241862A1
公开(公告)日:2021-08-05
申请号:US17163432
申请日:2021-01-30
Applicant: Cytel Inc.
Inventor: Jaydeep Bhattacharya , James Bolognese , Alexandre Buer , Eric Edwards , Stanley Y. Huang , Yannis Jemiai , Cyrus Mehta , Nitin Patel , Anne Pelz , Ajay Prabhakar Sathe , Joshua A. Schultz , Pralay Senchaudhuri
IPC: G16H10/20
Abstract: A method, according to some implementations, includes receiving, via at least one processor, output data of a plurality of trial design simulations for a plurality of scenarios and evaluating, via the at least one processor, the output data to determine changes in performance over the plurality of scenarios. The method may further include generating, via the at least one processor, visual tornado diagram data structured to generate a visual tornado diagram on an electronic display of an electronic device and transmitting, via the at least one processor, the visual tornado diagram data to the electronic device.
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